The Detail page: representing the detail information for virus-host related ncRNA interaction;
The Network page: representing the interaction sub-network of interacting ncRNA/Interactor.
- Detail
- Binding
- Network
| Detail: | |
| Vhid: | VVID00010866 |
|---|---|
| Virus: | Autographa californica nucleopolyhedrovirus(AcMNPV) |
| Host Species: | Autographa californica |
| ncRNA Source: | Virus |
| ncRNA Category: | miRNA |
| ncRNA Symbol: | AcMNPV-miR-1 |
| Tissue: | Sf9 cells infected with AcMNPV (10 PFU/cell) |
| Expression Direction of ncRNA: | - |
| Interactor in Virus or Host: | Virus |
| Interactor Category: | mRNA |
| Interactor Symbol: | odv-e25 |
| Expression Direction of Interactor: | Downregulation |
| Validated Method: | luciferase reporter assays, photoactivatable cross-linking and immunoprecipitation(PAR-CLIP), and deep sequencing and qRT-PCR. |
| PMID: | 24027316 |
| Detailed Description: | Here we report the identification and characterization of an miRNA encoded by Autographa californica nucleopolyhedrovirus. The identified miRNA, AcMNPV-miR-1, perfectly matched a segment in the coding sequence of the viral gene ODV-E25 and downregulated ODV-E25 mRNA expression, which likely resulted in a reduction of infectious budded virions and accelerated the formation of occlusion-derived virions. . |
The 'First Node' or 'Second Node' option represents the sub-network of interacting ncRNA/Interactor with the first or second interaction node,
the 'Both the Nodes' option represents the sub-network of interacting ncRNA/Interactor with both of interaction nodes.
The 'First Neighbour' represents the sub-network of direct interacting with the center node,
the 'Second Neighbour' represents the sub-network of direct or second step interacting with the center node.
Interaction sub-network based on the two nodes of this interaction may help the researchers represents all interacting partners immediately.