The Detail page: representing the detail information for virus-host related ncRNA interaction;
The Network page: representing the interaction sub-network of interacting ncRNA/Interactor.
- Detail
- Binding
- Network
| Detail: | |
| Vhid: | VHID00010862 |
|---|---|
| Virus: | Rhesus lymphocryptovirus(rLCV) |
| Host Species: | Macaca mulatta |
| ncRNA Source: | Virus |
| ncRNA Category: | miRNA |
| ncRNA Symbol: | rlcv-mir-rL1-8 |
| Tissue: | rLCV-infected rhesus macaquerLCLs |
| Expression Direction of ncRNA: | - |
| Interactor in Virus or Host: | Host |
| Interactor Category: | Protein |
| Interactor Symbol: | NFKB1 |
| Expression Direction of Interactor: | Downregulation |
| Validated Method: | luciferase reporter assays, photoactivatable cross-linking and immunoprecipitation(PAR-CLIP), and deep sequencing and qRT-PCR. |
| PMID: | 24257599 |
| Detailed Description: | These data demonstrate that miR-rL1-8 can functionally substitute for miRBART5 and that miR-BART5 and miR-BART16 negatively regulate NFKB signaling by directly targeting the LMP1 3'UTR. |
The 'First Node' or 'Second Node' option represents the sub-network of interacting ncRNA/Interactor with the first or second interaction node,
the 'Both the Nodes' option represents the sub-network of interacting ncRNA/Interactor with both of interaction nodes.
The 'First Neighbour' represents the sub-network of direct interacting with the center node,
the 'Second Neighbour' represents the sub-network of direct or second step interacting with the center node.
Interaction sub-network based on the two nodes of this interaction may help the researchers represents all interacting partners immediately.