Detail Information

Basic Information:


  VIRBase ID:  

VVID00000246

  Virus:  

Human immunodeficiency virus 1 (HIV-1)

  Host:  

Homo sapiens

  Confidence Score:  

0.8808

  Interaction Type:  

Virus-Virus interaction

Interactor Information:


Interactor1 Interactor2
Symbol hiv1-miR-TAR-5p LTR
miRBase
Accession/Entrez ID		 MIMAT0006016 LTR
Organism Human immunodeficiency virus 1 (HIV-1) Human immunodeficiency virus 1 (HIV-1)
Category miRNA mRNA
Alias - -

Interaction Network (The top 100 interactions):


Interactor1: hiv1-miR-TAR-5p
Interactor2: LTR

Evidence Support:


Strong-Evidence Luciferase reporter assay//Northern blot
Support Database ViRBase

References:


PMID 22936931 Target region LTR
Source ViRBase Interactor1 expression None
Tissue or cell line Jurkat cells//MT-4 T cells Interactor2 expression Downregulation
Description Table 1 includes the RNAi pathway related gene products that are targeted by HIV-1 microRNAs. List of published HIV-1 microRNAs and their target HIV-1 and cellular gene products.The target interactions of HIV-1 microRNAs with its mRNA seem to function as viral genome regulators.

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