Detail Information

Basic Information:


  VIRBase ID:  

VVID00000201

  Virus:  

Human gammaherpesvirus 8 (Kaposi's sarcoma herpesvirus, KSHV)

  Host:  

Homo sapiens

  Confidence Score:  

0.8808

  Interaction Type:  

Virus-Virus interaction

Interactor Information:


Interactor1 Interactor2
Symbol kshv-miR-K12-7-3p ORF50
miRBase
Accession/Entrez ID
MIMAT0002187 4961526
Organism Human gammaherpesvirus 8 (Kaposi's sarcoma herpesvirus, KSHV) Human gammaherpesvirus 8 (Kaposi's sarcoma herpesvirus, KSHV)
Category miRNA protein
Alias - HHV8GK18_gp52

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate kshv-miR-K12-7-3p
Exosome Jurkat-derived T cell line (J77cl20)     21505438

Interaction Network (The top 100 interactions):


Interactor1: kshv-miR-K12-7-3p
Interactor2: ORF50

Evidence Support:


Strong-Evidence Dual luciferase reporter assay//Western blot
Support Database VmiReg

References:


PMID 21283761 Target region None
Source VmiReg Interactor1 expression None
Tissue or cell line 293 cells//Bac36 cells//DG75 B-lymphoma cells//HEK293 cells Interactor2 expression None
Description We report here that miR-K12-7 directly targets the replication and transcription activator (RTA[ORF50]) encoded by open reading frame 50.

Starting a new search, please wait ...