Basic Information:
VIRBase ID:
VVID00000165
Virus:
Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)
Host:
Homo sapiens
Confidence Score:
0.9526
Interaction Type:
Virus-Virus interaction
Interactor Information:
|
Interactor1 |
Interactor2 |
Symbol |
ebv-miR-BHRF1-3 |
BRLF1 |
miRBase Accession/Entrez ID |
MIMAT0000998 |
3783727 |
Organism |
Human gammaherpesvirus 4 (Epstein-Barr virus, EPV) |
Human gammaherpesvirus 4 (Epstein-Barr virus, EPV) |
Category |
miRNA |
mRNA |
Alias |
-
|
HHV4_BRLF1
|
Interaction Network (The top 100 interactions):
Interactor1: ebv-miR-BHRF1-3 |
|
Interactor2: BRLF1 |
|
Evidence Support:
Strong-Evidence |
IFA//Luciferase reporter assay//qRT-PCR |
Support Database |
ViRBase
|
References:
PMID |
18378902 |
Target region |
3'UTR |
Source |
ViRBase
|
Interactor1 expression |
None |
Tissue or cell line |
293T cells//HEK293T cells//MRC5 cells |
Interactor2 expression |
Downregulation |
Description |
EBV (gamma-herpesvirus) miR-BHRF1-3 and miR-BART15 likely target BZLF1 and BRLF1, which share their 3'UTR (Table 1 and Table 4C). |