Detail Information

Basic Information:


  VIRBase ID:  

VHID00706754

  Virus:  

SARS-CoV-2 (NC_045512.2)

  Host:  

Homo sapiens

  Confidence Score:  

0.2381

  Interaction Type:  

Virus-Host interaction

Interactor Information:


Interactor1 Interactor2
Symbol sars-cov-2-mir-R3-3p HIF1A
miRBase
Accession/Entrez ID		 sars-cov-2-mir-R3-3p 3091
Organism SARS-CoV-2 (NC_045512.2) Homo sapiens
Category miRNA mRNA
Alias - bHLHe78//HIF-1-alpha//HIF-1A//HIF-1alpha//HIF1//HIF1-ALPHA//MOP1//PASD8

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR HIF1A
chr14:62211965(+) A-I      intronic
chr14:62211998(+) A-I      intronic
chr14:62211955(+) A-I      intronic
chr14:62184574(+) A-I      intronic
chr14:62213279(+) A-I      intronic
chr14:62213226(+) A-I      intronic
chr14:62213195(+) A-I      intronic
chr14:62213190(+) A-I      intronic
chr14:62209437(+) A-I      intronic
chr14:62212015(+) A-I      intronic
chr14:62209442(+) A-I      intronic
chr14:62209481(+) A-I      intronic
chr14:62205567(+) A-I      intronic
chr14:62209499(+) A-I      intronic
chr14:62211945(+) A-I      intronic
chr14:62168917(+) A-I      intronic
chr14:62213261(+) A-I      intronic
chr14:62213333(+) A-I      intronic
chr14:62213381(+) A-I      intronic
chr14:62168966(+) A-I      intronic
chr14:62212863(+) A-I      intronic
chr14:62210051(+) A-I      intronic
chr14:62177523(+) A-I      intronic
chr14:62177997(+) A-I      intronic
chr14:62209523(+) A-I      intronic
chr14:62213348(+) A-I      intronic
chr14:62169039(+) A-I      intronic
chr14:62208153(+) A-I      intronic
chr14:62168960(+) A-I      intronic
chr14:62209455(+) A-I      intronic
chr14:62212746(+) A-I      intronic
chr14:62169030(+) A-I      intronic
chr14:62209895(+) A-I      intronic
chr14:62209395(+) A-I      intronic
chr14:62181503(+) A-I      intronic
chr14:62212686(+) A-I      intronic
chr14:62177647(+) A-I      intronic
chr14:62168950(+) A-I      intronic
chr14:62209972(+) A-I      intronic
chr14:62213185(+) A-I      intronic
chr14:62213334(+) A-I      intronic
chr14:62177658(+) A-I      intronic
chr14:62213251(+) A-I      intronic
chr14:62210988(+) A-I      intronic
chr14:62207592(+) A-I      Syn:Ala->Ala
chr14:62175889(+) A-I      intronic
chr14:62182516(+) A-I      intronic
chr14:62209349(+) A-I      intronic
chr14:62178026(+) A-I      intronic
chr14:62196145(+) A-I      intronic
chr14:62211059(+) A-I      intronic
chr14:62209394(+) A-I      intronic
chr14:62198868(+) A-I      intronic
chr14:62209418(+) A-I      intronic
chr14:62212018(+) A-I      intronic
chr14:62213365(+) A-I      intronic
chr14:62212687(+) A-I      intronic
chr14:62209593(+) A-I      intronic
chr14:62209588(+) A-I      intronic
chr14:62211018(+) A-I      intronic
chr14:62178062(+) A-I      intronic
chr14:62211065(+) A-I      intronic
chr14:62213239(+) A-I      intronic
chr14:62213263(+) A-I      intronic
chr14:62209890(+) A-I      intronic
chr14:62211159(+) A-I      intronic
chr14:62178052(+) A-I      intronic
chr14:62177706(+) A-I      intronic
chr14:62211033(+) A-I      intronic
chr14:62211009(+) A-I      intronic
chr14:62177524(+) A-I      intronic
chr14:62209889(+) A-I      intronic
chr14:62209440(+) A-I      intronic
chr14:62175745(+) A-I      intronic
chr14:62188997(+) A-I      intronic
chr14:62168944(+) A-I      intronic
chr14:62209870(+) A-I      intronic
chr14:62189221(+) A-I      intronic
chr14:62178002(+) A-I      intronic
chr14:62209482(+) A-I      intronic
chr14:62182554(+) A-I      intronic
chr14:62209509(+) A-I      intronic
chr14:62210063(+) A-I      intronic
chr14:62209974(+) A-I      intronic
chr14:62211130(+) A-I      intronic
chr14:62207030(+) A-I      intronic
chr14:62213222(+) A-I      intronic
chr14:62204625(+) A-I      intronic
chr14:62213347(+) A-I      intronic
chr14:62208223(+) A-I      intronic
chr14:62209372(+) A-I      intronic
chr14:62175782(+) A-I      intronic
chr14:62177501(+) A-I      intronic
chr14:62209947(+) A-I      intronic
chr14:62211061(+) A-I      intronic
chr14:62213234(+) A-I      intronic
chr14:62209405(+) A-I      intronic
chr14:62209491(+) A-I      intronic
chr14:62168970(+) A-I      intronic
chr14:62209515(+) A-I      intronic
chr14:62209471(+) A-I      intronic
chr14:62177710(+) A-I      intronic
chr14:62187870(+) A-I      intronic
chr14:62177987(+) A-I      intronic
chr14:62209524(+) A-I      intronic
chr14:62177657(+) A-I      intronic
chr14:62178009(+) A-I      intronic
chr14:62205734(+) A-I      intronic
chr14:62209919(+) A-I      intronic
chr14:62208309(+) A-I      intronic
chr14:62209420(+) A-I      intronic
chr14:62213375(+) A-I      intronic
chr14:62209969(+) A-I      intronic
chr14:62209786(+) A-I      intronic
chr14:62210993(+) A-I      intronic
chr14:62210011(+) A-I      intronic
chr14:62168936(+) A-I      intronic
chr14:62187878(+) A-I      intronic
chr14:62184932(+) A-I      intronic
chr14:62211175(+) A-I      intronic
chr14:62207057(+) A-I      intronic
chr14:62211010(+) A-I      intronic
chr14:62182536(+) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED HIF1A
chr14:62168917(+) A-I intron -    15342557
chr14:62168936(+) A-I intron -    15342557
chr14:62168944(+) A-I intron -    15342557
chr14:62168950(+) A-I intron -    15342557
chr14:62168960(+) A-I intron -    15342557
chr14:62168966(+) A-I intron -    15342557
chr14:62168970(+) A-I intron -    15342557
chr14:62169030(+) A-I intron -    15342557
chr14:62169039(+) A-I intron -    15342557
chr14:62169048(+) A-I intron -    15342557
chr14:62175776(+) A-I intron -    22327324
chr14:62177729(+) A-I intron -    22327324
chr14:62178061(+) A-I intron -    22327324
chr14:62178077(+) A-I intron -    22327324
chr14:62178087(+) A-I intron -    22327324
chr14:62187859(+) A-I intron -    22327324
chr14:62194582(+) A-I intron -    22327324
chr14:62205593(+) A-I intron -    22327324
chr14:62205668(+) A-I intron -    22327324
chr14:62205755(+) A-I intron -    22327324
chr14:62209962(+) A-I intron -    22327324
chr14:62213260(+) A-I intron -    22327324
chr14:62213312(+) A-I intron -    22327324
chr14:62213321(+) A-I intron -    22327324
chr14:62175776(+) T-C intron -    22484847
chr14:62175797(+) T-C intron -    22484847
chr14:62177702(+) T-C intron -    22484847
chr14:62177936(+) T-C intron -    22484847
chr14:62178015(+) T-C intron -    22484847
chr14:62178061(+) T-C intron -    22484847
chr14:62178076(+) T-C intron -    22484847
chr14:62178077(+) T-C intron -    22484847
chr14:62178082(+) T-C intron -    22484847
chr14:62178087(+) T-C intron -    22484847
chr14:62182549(+) G-A intron -    22484847
chr14:62182660(+) T-C intron -    22484847
chr14:62182682(+) T-C intron -    22484847
chr14:62182691(+) T-C intron -    22484847
chr14:62184535(+) T-C intron -    22484847
chr14:62184537(+) T-C intron -    22484847
chr14:62184576(+) T-C intron -    22484847
chr14:62184627(+) T-C intron -    22484847
chr14:62184656(+) T-C intron -    22484847
chr14:62184657(+) T-C intron -    22484847
chr14:62184700(+) T-C intron -    22484847
chr14:62184953(+) T-C intron -    22484847
chr14:62184954(+) T-C intron -    22484847
chr14:62184960(+) T-C intron -    22484847
chr14:62187703(+) T-C intron -    22484847
chr14:62187859(+) T-C intron -    22484847
chr14:62187876(+) T-C intron -    22484847
chr14:62188997(+) A-G intron -    22484847
chr14:62189005(+) T-C intron -    22484847
chr14:62189025(+) T-C intron -    22484847
chr14:62189039(+) T-C intron -    22484847
chr14:62189078(+) T-C intron -    22484847
chr14:62189079(+) T-C intron -    22484847
chr14:62189172(+) T-C intron -    22484847
chr14:62189228(+) T-C intron -    22484847
chr14:62192167(+) T-C intron -    22484847
chr14:62192209(+) T-C intron -    22484847
chr14:62192230(+) T-C intron -    22484847
chr14:62192235(+) T-C intron -    22484847
chr14:62192270(+) T-C intron -    22484847
chr14:62192271(+) T-C intron -    22484847
chr14:62192293(+) T-C intron -    22484847
chr14:62192306(+) T-C intron -    22484847
chr14:62192310(+) T-C intron -    22484847
chr14:62192326(+) T-C intron -    22484847
chr14:62192329(+) T-C intron -    22484847
chr14:62192334(+) T-C intron -    22484847
chr14:62192405(+) T-C intron -    22484847
chr14:62192635(+) T-C intron -    22484847
chr14:62192640(+) T-C intron -    22484847
chr14:62192711(+) T-C intron -    22484847
chr14:62192715(+) T-C intron -    22484847
chr14:62192716(+) T-C intron -    22484847
chr14:62192717(+) T-C intron -    22484847
chr14:62192720(+) T-C intron -    22484847
chr14:62192739(+) T-C intron -    22484847
chr14:62192754(+) T-C intron -    22484847
chr14:62192755(+) T-C intron -    22484847
chr14:62192810(+) T-C intron -    22484847
chr14:62192811(+) T-C intron -    22484847
chr14:62192819(+) T-C intron -    22484847
chr14:62194484(+) T-C intron -    22484847
chr14:62194545(+) T-C intron -    22484847
chr14:62194556(+) T-C intron -    22484847
chr14:62194563(+) T-C intron -    22484847
chr14:62194582(+) T-C intron -    22484847
chr14:62194585(+) T-C intron -    22484847
chr14:62194601(+) T-C intron -    22484847
chr14:62194653(+) T-C intron -    22484847
chr14:62194654(+) T-C intron -    22484847
chr14:62196085(+) T-C intron -    22484847
chr14:62196192(+) C-A intron -    22484847
chr14:62198638(+) T-C intron -    22484847
chr14:62198692(+) T-C intron -    22484847
chr14:62198726(+) T-C intron -    22484847
chr14:62200007(+) T-C intron -    22484847
chr14:62202711(+) C-T intron -    22484847
chr14:62202835(+) T-C intron -    22484847
chr14:62205593(+) T-C intron -    22484847
chr14:62205611(+) T-C intron -    22484847
chr14:62205668(+) T-C intron -    22484847
chr14:62205715(+) T-C intron -    22484847
chr14:62205719(+) T-C intron -    22484847
chr14:62205720(+) T-C intron -    22484847
chr14:62205750(+) T-C intron -    22484847
chr14:62205755(+) T-C intron -    22484847
chr14:62205764(+) T-C intron -    22484847
chr14:62207011(+) T-C intron -    22484847
chr14:62207056(+) T-C intron -    22484847
chr14:62208113(+) T-C intron -    22484847
chr14:62208318(+) T-C intron -    22484847
chr14:62208359(+) T-C intron -    22484847
chr14:62208360(+) T-C intron -    22484847
chr14:62208366(+) T-C intron -    22484847
chr14:62209341(+) T-C intron -    22484847
chr14:62209347(+) T-C intron -    22484847
chr14:62209359(+) T-C intron -    22484847
chr14:62209401(+) T-C intron -    22484847
chr14:62209436(+) T-C intron -    22484847
chr14:62209439(+) T-C intron -    22484847
chr14:62209471(+) A-G intron -    22484847
chr14:62209480(+) T-C intron -    22484847
chr14:62209528(+) T-C intron -    22484847
chr14:62209817(+) T-C intron -    22484847
chr14:62209886(+) T-C intron -    22484847
chr14:62209954(+) T-C intron -    22484847
chr14:62209959(+) T-C intron -    22484847
chr14:62209962(+) T-C intron -    22484847
chr14:62209972(+) A-G intron -    22484847
chr14:62209986(+) T-C intron -    22484847
chr14:62210011(+) A-G intron -    22484847
chr14:62210067(+) T-C intron -    22484847
chr14:62210068(+) T-C intron -    22484847
chr14:62210080(+) T-C intron -    22484847
chr14:62211038(+) T-C intron -    22484847
chr14:62211060(+) T-C intron -    22484847
chr14:62211209(+) T-C intron -    22484847
chr14:62212019(+) T-C intron -    22484847
chr14:62212842(+) T-C intron -    22484847
chr14:62212859(+) T-C intron -    22484847
chr14:62213153(+) T-C intron -    22484847
chr14:62213192(+) T-C intron -    22484847
chr14:62213219(+) T-C intron -    22484847
chr14:62213246(+) T-C intron -    22484847
chr14:62213260(+) T-C intron -    22484847
chr14:62213312(+) T-C intron -    22484847
chr14:62213321(+) T-C intron -    22484847
chr14:62213326(+) T-C intron -    22484847
chr14:62213330(+) T-C intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase HIF1A
chr14:62162258-62162259(+) m6A 5'UTR//exon       24284625//24981863//22575960//22608085
chr14:62162348-62162349(+) m6A 5'UTR//exon       24284625//24981863//26404942//22575960
chr14:62162418-62162419(+) m6A 5'UTR//exon       24284625//24981863//22575960
chr14:62162500-62162501(+) m6A 5'UTR//exon       24981863//22575960
chr14:62162511-62162512(+) m6A 5'UTR//exon       24981863//22575960
chr14:62164347-62164348(+) m6A 5'UTR//intron       24981863
chr14:62164423-62164424(+) m6A 5'UTR//intron       24981863
chr14:62193506-62193507(+) m6A CDS//exon       26404942
chr14:62193513-62193514(+) m6A CDS//exon       26404942
chr14:62194241-62194242(+) m6A CDS//exon       26404942
chr14:62194274-62194275(+) m6A CDS//exon       26404942
chr14:62199168-62199169(+) m6A CDS       26404942
chr14:62199209-62199210(+) m6A CDS       26404942
chr14:62199229-62199230(+) m6A CDS       26404942
chr14:62200868-62200869(+) m6A CDS       26404942
chr14:62200883-62200884(+) m6A CDS       26404942
chr14:62200929-62200930(+) m6A CDS       26404942
chr14:62203646-62203647(+) m6A CDS//exon       26404942
chr14:62204991-62204992(+) m6A CDS//intron       26404942
chr14:62205012-62205013(+) m6A CDS//intron       26404942
chr14:62207625-62207626(+) m6A CDS//exon       24284625//24981863//26404942//27773535//22608085
chr14:62207639-62207640(+) m6A CDS//exon       24284625//24981863//26404942//27773535//22608085
chr14:62207688-62207689(+) m6A CDS//exon       24284625//24981863//26404942//27773535//22608085
chr14:62207701-62207702(+) m6A CDS//exon       24284625//24981863//26404942//27773535//22608085
chr14:62207713-62207714(+) m6A CDS//exon       24284625//24981863//26404942//27773535//22608085
chr14:62207763-62207764(+) m6A CDS//exon       24284625//24981863//26404942//27773535//22608085
chr14:62207808-62207809(+) m6A CDS//exon       24284625//24981863//26404942//27773535//22608085
chr14:62207821-62207822(+) m6A CDS//exon       24284625//24981863//26404942//27773535//22575960//22608085
chr14:62207846-62207847(+) m6A CDS//exon       24981863//26404942//27773535//22575960//22608085
chr14:62211443-62211444(+) m6A CDS       24981863//26404942//27773535//22575960//22608085
chr14:62211497-62211498(+) m6A CDS       26404942//27773535//22575960
chr14:62212377-62212378(+) m6A exon//intron       27773535//22575960
chr14:62212382-62212383(+) m6A exon//intron       27773535//22575960
chr14:62212411-62212412(+) m6A CDS//exon//intron       22575960
chr14:62212491-62212492(+) m6A CDS//exon//intron       22575960
chr14:62212513-62212514(+) m6A CDS//exon//intron       22575960
chr14:62213664-62213665(+) m6A 3'UTR//CDS//exon       26404942
chr14:62213753-62213754(+) m6A 3'UTR//CDS//exon       26404942
chr14:62213833-62213834(+) m6A 3'UTR//exon       26404942
chr14:62214327-62214328(+) m6A 3'UTR       26404942
chr14:62214372-62214373(+) m6A 3'UTR       26404942
chr14:62214379-62214380(+) m6A 3'UTR       26404942
chr14:62214627-62214628(+) m6A 3'UTR       26404942
chr14:62214674-62214675(+) m6A 3'UTR       26404942
chr14:62214681-62214682(+) m6A 3'UTR       26404942
chr14:62214957-62214958(+) m6A 3'UTR       27773535
chr14:62214970-62214971(+) m6A 3'UTR       27773535

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate HIF1A
Chromatin K562 cells     -
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Cytosol HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     -
Endoplasmic reticulum Human fibrosarcoma cells (HT1080)     25753659
Exosome Blood     -
Insoluble cytoplasm K562 cells     -
Nucleoplasm K562 cells     -
Nucleus Colon cancer cells     24393600
Nucleus HCC cell line (HepG2)|HeLa-S3 cells     -
Ribosome HEK-293 cells     22199352

Interaction Network (The top 100 interactions):


Interactor1: sars-cov-2-mir-R3-3p
Interactor2: HIF1A

Evidence Support:


Prediction-Evidence miRanda//miRDB//Targetscan
Support Database ViRBase

References:


PMID 33398248 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line None Interactor2 expression None
Description Cytotoxin and gene regulation associated genes targeted by SARS-CoV-2 encoded miRNAs.

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