Detail Information

Basic Information:


  VIRBase ID:  

VHID00706683

  Virus:  

SARS-CoV-2 (NC_045512.2)

  Host:  

Homo sapiens

  Confidence Score:  

0.2381

  Interaction Type:  

Virus-Host interaction

Interactor Information:


Interactor1 Interactor2
Symbol sars-cov-2-mir-D6-3p AKT1
miRBase
Accession/Entrez ID		 sars-cov-2-mir-D6-3p 207
Organism SARS-CoV-2 (NC_045512.2) Homo sapiens
Category miRNA mRNA
Alias - AKT//PKB//PKB-ALPHA//PRKBA//RAC//RAC-ALPHA

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase AKT1
chr14:105236380-105236381(-) Y 3'UTR//exon//intron       26075521
chr14:105236381-105236382(-) Y 3'UTR//exon//intron       26075521
chr14:105236391-105236392(-) m6A 3'UTR//exon//intron       24284625//24981863
chr14:105236422-105236423(-) m6A 3'UTR//exon//intron       24284625//24981863
chr14:105236487-105236488(-) m6A 3'UTR//exon//intron       24284625//24981863
chr14:105236665-105236666(-) m6A 3'UTR//exon//intron       24284625
chr14:105236735-105236736(-) m6A 3'UTR//CDS//exon//intron       27773535
chr14:105237147-105237148(-) m6A 3'UTR//CDS//exon       27773535//27773536
chr14:105237286-105237287(-) m6A exon//intron       27773535//27773536
chr14:105237736-105237737(-) m6A exon//intron       25456834//24981863
chr14:105237779-105237780(-) m6A exon//intron       24284625//25456834
chr14:105237801-105237802(-) m6A exon//intron       24284625//25456834
chr14:105237821-105237822(-) m6A exon//intron       24284625//25456834
chr14:105239226-105239227(-) m6A CDS//exon       27773536//22575960
chr14:105239328-105239329(-) m6A CDS//exon       24284625//25456834//22575960
chr14:105239394-105239395(-) m6A CDS//exon//intron       24284625//25456834//24981863//27773535//27371828//22575960
chr14:105239418-105239419(-) m6A CDS//exon//intron       24284625//25456834//24981863//28052920//27773535//27371828//22575960
chr14:105239471-105239472(-) m6A exon//intron       24284625//25456834//24981863//27773535//27371828//22575960//22608085
chr14:105239622-105239623(-) m6A CDS//exon       24981863//27773535//22575960
chr14:105239669-105239670(-) m6A CDS//exon       27773535//22575960
chr14:105239679-105239680(-) Am CDS//exon       -
chr14:105239696-105239697(-) m6A CDS//exon       27773535//22575960
chr14:105239708-105239709(-) m6A CDS//exon       27773535//22575960
chr14:105239798-105239799(-) m6A CDS//exon       27773535//22575960
chr14:105239834-105239835(-) m6A CDS//exon       27773535//22575960
chr14:105239876-105239877(-) m6A CDS//exon       27773535//22575960
chr14:105240295-105240296(-) m6A CDS//exon       24284625//27773535//27371828//27773536
chr14:105241296-105241297(-) m6A CDS//exon       24284625//27371828//27773536
chr14:105241311-105241312(-) m6A CDS//exon       24284625//27773535//27371828//27773536
chr14:105241543-105241544(-) m6A CDS//exon       27371828//27773536
chr14:105241896-105241897(-) m6A exon//intron       27371828
chr14:105241943-105241944(-) m6A exon//intron       27371828
chr14:105242067-105242068(-) m6A CDS//exon       24284625//25456834//27371828//27773536
chr14:105242110-105242111(-) m6A CDS//exon       24284625//25456834//27773535//27371828//27773536
chr14:105242125-105242126(-) m6A CDS//exon       24284625//25456834//27773535//27371828//27773536
chr14:105242226-105242227(-) m6A exon//intron       27773536
chr14:105242243-105242244(-) m6A exon//intron       27773536
chr14:105243008-105243009(-) m6A CDS//exon       24284625
chr14:105243041-105243042(-) m6A CDS//exon       24284625
chr14:105243129-105243130(-) m6A exon//intron       24284625
chr14:105246462-105246463(-) m6A CDS//exon       24284625
chr14:105246538-105246539(-) m6A CDS//exon       24284625
chr14:105259288-105259289(-) m6A 5'UTR//intron       -
chr14:105259579-105259580(-) m6A 5'UTR//exon//intron       24981863//27371828//27773536
chr14:105259588-105259589(-) m6A 5'UTR//exon//intron       24981863//27371828//27773536
chr14:105259879-105259880(-) m6A 5'UTR//exon//intron       24981863
chr14:105259889-105259890(-) m6A 5'UTR//exon//intron       24981863
chr14:105259911-105259912(-) m6A 5'UTR//exon//intron       24981863
chr14:105261372-105261373(-) m6A exon//intron       -
chr14:105262072-105262073(-) m6A 5'UTR//exon       25456834//24981863//27371828//27773536

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate AKT1
Chromatin K562 cells     -
Cytosol HeLa-S3 cells|K562 cells     -
Exosome Blood     -
Insoluble cytoplasm HCC cell line (HepG2)     -
Nucleolus K562 cells     -
Nucleoplasm K562 cells     -
Nucleus K562 cells     -
Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):


Interactor1: sars-cov-2-mir-D6-3p
Interactor2: AKT1

Evidence Support:


Prediction-Evidence miRanda//miRDB//Targetscan
Support Database ViRBase

References:


PMID 33398248 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line None Interactor2 expression None
Description Cytotoxin and gene regulation associated genes targeted by SARS-CoV-2 encoded miRNAs.

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