Detail Information

Basic Information:


  VIRBase ID:  

VHID00706651

  Virus:  

SARS-CoV-2 (NC_045512.2)

  Host:  

Homo sapiens

  Confidence Score:  

0.2381

  Interaction Type:  

Virus-Host interaction

Interactor Information:


Interactor1 Interactor2
Symbol sars-cov-2-mir-D14-3p CDK1
miRBase
Accession/Entrez ID		 sars-cov-2-mir-D14-3p 983
Organism SARS-CoV-2 (NC_045512.2) Homo sapiens
Category miRNA mRNA
Alias - CDC2//CDC28A//P34CDC2

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR CDK1
chr10:62550166(+) A-I      intronic

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase CDK1
chr10:62538228-62538229(+) m6A 5'UTR//exon//intron       24981863
chr10:62538419-62538420(+) m6A 5'UTR//intron       27773535
chr10:62543255-62543256(+) m6A exon//intron       24981863//27773535
chr10:62543291-62543292(+) m6A exon//intron       27773535
chr10:62544490-62544491(+) m6A CDS//exon       26404942
chr10:62544497-62544498(+) m6A CDS//exon       26404942
chr10:62544532-62544533(+) m6A CDS//exon       26404942
chr10:62544595-62544596(+) m6A CDS//exon       26404942
chr10:62552015-62552016(+) m6A 3'UTR//CDS       26404942
chr10:62554391-62554392(+) m6A 3'UTR       27773535
chr10:62554506-62554507(+) m6A 3'UTR       27773535

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate CDK1
Chromatin K562 cells     -
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Cytosol K562 cells     -
Exosome Blood     -
Nucleolus K562 cells     -
Nucleoplasm K562 cells     -
Nucleus HeLa-S3 cells     -
Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):


Interactor1: sars-cov-2-mir-D14-3p
Interactor2: CDK1

Evidence Support:


Prediction-Evidence miRanda//miRDB//Targetscan
Support Database ViRBase

References:


PMID 33398248 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line None Interactor2 expression None
Description Cytotoxin and gene regulation associated genes targeted by SARS-CoV-2 encoded miRNAs.

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