Basic Information:

  VIRBase ID:  

VHID00704955

  Virus:  

Human immunodeficiency virus 1 (HIV-1)

  Host:  

Homo sapiens

  Confidence Score:  

0.2494

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hiv1-miR-TAR-3p:  MIMAT0006017          DCAF11:  NM_001163484     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hiv1-miR-TAR-3p	DCAF11
miRBase Accession/Entrez ID	MIMAT0006017	80344
Organism	Human immunodeficiency virus 1 (HIV-1)	Homo sapiens
Category	miRNA	mRNA
Alias	-	GL014//PRO2389//WDR23

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	DCAF11	chr14:24590194(+) A-I      NonSyn:Lys->Glu chr14:24590197(+) A-I      NonSyn:Lys->Glu chr14:24590198(+) A-I      NonSyn:Lys->Arg chr14:24590163(+) A-I      Syn:Gln->Gln chr14:24590196(+) A-I      Syn:Lys->Lys chr14:24594248(+) A-I      3'UTR chr14:24594249(+) A-I      3'UTR chr14:24594279(+) A-I      3'UTR chr14:24594240(+) A-I      3'UTR chr14:24594261(+) A-I      3'UTR chr14:24594250(+) A-I      3'UTR chr14:24594273(+) A-I      3'UTR chr14:24594239(+) A-I      3'UTR chr14:24594220(+) A-I      3'UTR chr14:24594209(+) A-I      3'UTR chr14:24593860(+) A-I      3'UTR chr14:24593936(+) A-I      3'UTR chr14:24594381(+) A-I      3'UTR chr14:24594210(+) A-I      3'UTR chr14:24593851(+) A-I      3'UTR chr14:24593964(+) A-I      3'UTR chr14:24594102(+) A-I      3'UTR chr14:24594313(+) A-I      3'UTR chr14:24594142(+) A-I      3'UTR chr14:24594065(+) A-I      3'UTR chr14:24593995(+) A-I      3'UTR chr14:24594335(+) A-I      3'UTR chr14:24594106(+) A-I      3'UTR chr14:24593929(+) A-I      3'UTR chr14:24591578(+) A-I      intronic chr14:24591610(+) A-I      intronic chr14:24591620(+) A-I      intronic chr14:24594159(+) A-I      3'UTR chr14:24593953(+) A-I      3'UTR chr14:24594426(+) A-I      3'UTR chr14:24593989(+) A-I      3'UTR chr14:24594132(+) A-I      3'UTR chr14:24593937(+) A-I      3'UTR chr14:24594395(+) A-I      3'UTR chr14:24593837(+) A-I      3'UTR chr14:24594223(+) A-I      3'UTR chr14:24594147(+) A-I      3'UTR chr14:24593877(+) A-I      3'UTR chr14:24594022(+) A-I      3'UTR chr14:24594299(+) A-I      3'UTR chr14:24594031(+) A-I      3'UTR chr14:24594309(+) A-I      3'UTR chr14:24594133(+) A-I      3'UTR chr14:24594339(+) A-I      3'UTR chr14:24593996(+) A-I      3'UTR

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	DCAF11	chr14:24593837(+) A-I exon 5'UTR    15342557 chr14:24594022(+) A-I exon 5'UTR    15342557 chr14:24594065(+) A-I exon 5'UTR    15342557 chr14:24594106(+) A-I exon 5'UTR    15342557 chr14:24594133(+) A-I exon 5'UTR    15342557 chr14:24594210(+) A-I exon 5'UTR    15342557 chr14:24594223(+) A-I exon 5'UTR    15342557 chr14:24594299(+) A-I intron -    21960545 chr14:24593989(+) A-G intron -    22484847 chr14:24594395(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	DCAF11	chr14:24584089-24584090(+) m6A 5'UTR//exon       - chr14:24584744-24584745(+) m6A 5'UTR//exon//intron       - chr14:24584779-24584780(+) m6A 5'UTR//exon       24981863 chr14:24584816-24584817(+) m6A 5'UTR//CDS//exon       24209618//24981863 chr14:24584846-24584847(+) m6A 5'UTR//CDS//exon       24209618//24981863 chr14:24586190-24586191(+) m6A 5'UTR//CDS//exon//intron       24209618 chr14:24586512-24586513(+) Gm 3'UTR//CDS//exon//intron       - chr14:24592332-24592333(+) m6A CDS//exon//intron       - chr14:24592393-24592394(+) m6A 3'UTR//CDS//exon       - chr14:24594173-24594174(+) m6A 3'UTR       24981863 chr14:24594211-24594212(+) m6A 3'UTR       24981863

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	DCAF11	Cytosol HCC cell line (HepG2)|K562 cells     - Exosome Blood     - Nucleoplasm K562 cells     - Nucleus HCC cell line (HepG2)     - Ribosome Colon cancer cells     24393600

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	hiv1-miR-TAR-3p	l-685,458       5479543 Pha-665752       10461815

Interaction Network (The top 100 interactions):

Interactor1: hiv1-miR-TAR-3p
Interactor2: DCAF11

Evidence Support:

Prediction-Evidence	cRep//miRanda//PITA//Rep//RNAHybrid//Targetscan
Support Database	RepTar//VmiReg