Basic Information:

  VIRBase ID:  

VHID00704769

  Virus:  

Human immunodeficiency virus 1 (HIV-1)

  Host:  

Homo sapiens

  Confidence Score:  

0.2202

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hiv1-miR-TAR-3p:  MIMAT0006017          WDR77:  NR_133654     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hiv1-miR-TAR-3p	WDR77
miRBase Accession/Entrez ID	MIMAT0006017	79084
Organism	Human immunodeficiency virus 1 (HIV-1)	Homo sapiens
Category	miRNA	mRNA
Alias	-	HKMT1069//MEP-50//MEP50//Nbla10071//p44//p44/Mep50

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	WDR77	chr1:111988139(-) A-I      intronic chr1:111988529(-) A-I      intronic chr1:111988666(-) A-I      intronic

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	WDR77	chr1:111983647-111983648(-) m6A 3'UTR       24981863//27773535//22575960 chr1:111983779-111983780(-) m6A 3'UTR       27773535 chr1:111991468-111991469(-) m6A exon//intron       24284625 chr1:111991778-111991779(-) m6A CDS       24981863//27371828 chr1:111991799-111991800(-) m6A 5'UTR       25456834//24981863//27371828

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	WDR77	Chromatin K562 cells     - Cytosol K562 cells     - Exosome Blood     - Membrane HCC cell line (HepG2)     - Nucleoplasm K562 cells     - Nucleus HeLa-S3 cells|K562 cells     - Ribosome Colon cancer cells     24393600

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	hiv1-miR-TAR-3p	l-685,458       5479543 Pha-665752       10461815

Interaction Network (The top 100 interactions):

Interactor1: hiv1-miR-TAR-3p
Interactor2: WDR77

Evidence Support:

Prediction-Evidence	PITA//RNAHybrid
Support Database	VmiReg