Basic Information:

  VIRBase ID:  

VHID00704622

  Virus:  

Human immunodeficiency virus 1 (HIV-1)

  Host:  

Homo sapiens

  Confidence Score:  

0.2494

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hiv1-miR-TAR-3p:  MIMAT0006017          PKNOX2:  NM_001382341     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hiv1-miR-TAR-3p	PKNOX2
miRBase Accession/Entrez ID	MIMAT0006017	63876
Organism	Human immunodeficiency virus 1 (HIV-1)	Homo sapiens
Category	miRNA	mRNA
Alias	-	PREP2

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	PKNOX2	chr11:125118644(+) A-I      intronic chr11:125118666(+) A-I      intronic chr11:125118643(+) A-I      intronic chr11:125118658(+) A-I      intronic chr11:125118653(+) A-I      intronic chr11:125118648(+) A-I      intronic chr11:125118641(+) A-I      intronic chr11:125205607(+) A-I      intronic chr11:125083376(+) A-I      intronic chr11:125290259(+) A-I      intronic chr11:125120065(+) A-I      intronic chr11:125179467(+) A-I      intronic chr11:125225004(+) A-I      intronic chr11:125179377(+) A-I      intronic chr11:125224977(+) A-I      intronic chr11:125286022(+) A-I      intronic chr11:125285319(+) A-I      intronic chr11:125119711(+) A-I      intronic chr11:125177333(+) A-I      intronic chr11:125179469(+) A-I      intronic chr11:125082431(+) A-I      intronic chr11:125048421(+) A-I      intronic chr11:125179385(+) A-I      intronic chr11:125119841(+) A-I      intronic chr11:125120047(+) A-I      intronic chr11:125285321(+) A-I      intronic chr11:125179353(+) A-I      intronic chr11:125049630(+) A-I      intronic chr11:125068965(+) A-I      intronic chr11:125177246(+) A-I      intronic chr11:125179546(+) A-I      intronic chr11:125285392(+) A-I      intronic chr11:125068876(+) A-I      intronic chr11:125113757(+) A-I      intronic chr11:125285277(+) A-I      intronic chr11:125179554(+) A-I      intronic chr11:125285276(+) A-I      intronic chr11:125120086(+) A-I      intronic chr11:125260129(+) A-I      intronic chr11:125205603(+) A-I      intronic chr11:125069700(+) A-I      intronic chr11:125290432(+) A-I      intronic chr11:125068866(+) A-I      intronic chr11:125111520(+) A-I      intronic chr11:125113756(+) A-I      intronic chr11:125290017(+) A-I      intronic chr11:125062163(+) A-I      intronic chr11:125272769(+) A-I      intronic chr11:125282029(+) A-I      intronic chr11:125285234(+) A-I      intronic

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	PKNOX2	chr11:125300024-125300025(+) m6A 3'UTR//CDS//exon       - chr11:125301076-125301077(+) m6A 3'UTR//CDS//exon       - chr11:125301100-125301101(+) m6A 3'UTR//CDS//exon       - chr11:125301162-125301163(+) m6A 3'UTR//CDS//exon       25456834//22608085 chr11:125301266-125301267(+) m6A 3'UTR//CDS//exon       25456834//24981863//22608085 chr11:125301366-125301367(+) m6A 3'UTR//exon       25456834//24981863 chr11:125301439-125301440(+) m6A 3'UTR//exon       25456834//24981863//22608085 chr11:125301476-125301477(+) m6A 3'UTR//exon       25456834//24981863//22608085 chr11:125301498-125301499(+) m6A 3'UTR//exon       25456834//24981863//22608085 chr11:125301508-125301509(+) m6A 3'UTR//exon       25456834//24981863//22608085 chr11:125301549-125301550(+) m6A 3'UTR//exon       25456834//24981863//22608085 chr11:125301566-125301567(+) m6A 3'UTR//exon       25456834//24981863//22608085 chr11:125301619-125301620(+) m6A 3'UTR//exon       25456834//24981863//22608085 chr11:125301693-125301694(+) m6A 3'UTR//exon       25456834//24981863//22608085 chr11:125301713-125301714(+) m6A 3'UTR//exon       25456834//24981863//22608085 chr11:125301723-125301724(+) m6A 3'UTR//exon       25456834//24981863//22608085 chr11:125301764-125301765(+) m6A 3'UTR//exon       25456834//24981863//22608085 chr11:125301918-125301919(+) m6A 3'UTR//exon       25456834 chr11:125301968-125301969(+) m6A 3'UTR//exon       25456834

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	PKNOX2	Exosome Blood     -

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	hiv1-miR-TAR-3p	l-685,458       5479543 Pha-665752       10461815

Interaction Network (The top 100 interactions):

Interactor1: hiv1-miR-TAR-3p
Interactor2: PKNOX2

Evidence Support:

Prediction-Evidence	cRep//miRanda//PITA//Rep//RNAHybrid//Targetscan
Support Database	RepTar//VmiReg