Basic Information:

  VIRBase ID:  

VHID00702950

  Virus:  

Human immunodeficiency virus 1 (HIV-1)

  Host:  

Homo sapiens

  Confidence Score:  

0.2381

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hiv1-miR-TAR-3p:  MIMAT0006017          PRDX6:  NM_004905     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hiv1-miR-TAR-3p	PRDX6
miRBase Accession/Entrez ID	MIMAT0006017	9588
Organism	Human immunodeficiency virus 1 (HIV-1)	Homo sapiens
Category	miRNA	mRNA
Alias	-	1-Cys//aiPLA2//AOP2//HEL-S-128m//LPCAT-5//NSGPx//p29//PRX

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	PRDX6	chr1:173453022(+) A-I      intronic chr1:173452993(+) A-I      intronic

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	PRDX6	chr1:173446466-173446467(+) m6A 5'UTR       24284625//24981863//22575960 chr1:173446487-173446488(+) m6A 5'UTR//exon       24284625//24981863//22575960 chr1:173446627-173446628(+) m6A CDS//exon       24981863//22575960 chr1:173457077-173457078(+) m6A 3'UTR//exon       27773535 chr1:173457636-173457637(+) m6A 3'UTR       27773535 chr1:173457781-173457782(+) Y 3'UTR       26075521 chr1:173457869-173457870(+) m6A 3'UTR       27773535 chr1:173457917-173457918(+) m6A 3'UTR       27773535 chr1:173457940-173457941(+) m6A 3'UTR       27773535

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	PRDX6	Chromatin K562 cells     - Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Membrane K562 cells     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus HeLa-S3 cells|K562 cells     - Ribosome HEK-293 cells     22199352 Ribosome Colon cancer cells     24393600

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	hiv1-miR-TAR-3p	l-685,458       5479543 Pha-665752       10461815

Interaction Network (The top 100 interactions):

Interactor1: hiv1-miR-TAR-3p
Interactor2: PRDX6

Evidence Support:

Prediction-Evidence	cRep//miRanda//Targetscan
Support Database	RepTar//VmiReg