Basic Information:

  VIRBase ID:  

VHID00702714

  Virus:  

Human immunodeficiency virus 1 (HIV-1)

  Host:  

Homo sapiens

  Confidence Score:  

0.2202

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hiv1-miR-TAR-3p:  MIMAT0006017          DYRK2:  NM_006482     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hiv1-miR-TAR-3p	DYRK2
miRBase Accession/Entrez ID	MIMAT0006017	8445
Organism	Human immunodeficiency virus 1 (HIV-1)	Homo sapiens
Category	miRNA	mRNA
Alias	-	-

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	DYRK2	chr12:68047541(+) A-I      intronic

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	DYRK2	chr12:68042755-68042756(+) m6A 5'UTR//intron       24284625//24209618//25456834//24981863//27773536//22575960//22608085 chr12:68042806-68042807(+) m6A 5'UTR//intron       24284625//24209618//25456834//24981863//22575960//22608085 chr12:68042863-68042864(+) m6A 5'UTR//intron       24284625//24209618//24981863//22575960 chr12:68042927-68042928(+) m6A 5'UTR//CDS//exon//intron       24284625//24209618//24981863 chr12:68043588-68043589(+) m6A 5'UTR//CDS//exon//intron       24284625 chr12:68043656-68043657(+) m6A 5'UTR//CDS//exon//intron       24284625 chr12:68046406-68046407(+) m6A exon//intron       - chr12:68046463-68046464(+) m6A exon//intron       24284625//24209618//25456834//24981863//22608085 chr12:68046471-68046472(+) m6A exon//intron       24284625//24209618//25456834//24981863//22608085 chr12:68050944-68050945(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr12:68050990-68050991(+) m6A CDS       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr12:68051069-68051070(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr12:68051157-68051158(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr12:68051184-68051185(+) m6A CDS       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr12:68051199-68051200(+) m6A CDS       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr12:68051499-68051500(+) m6A CDS       24284625//24209618//24981863//22608085 chr12:68051516-68051517(+) m6A CDS       24284625//24209618//24981863//22608085 chr12:68051606-68051607(+) m6A CDS       24284625//24209618//24981863//22575960//22608085 chr12:68051711-68051712(+) m6A CDS       24284625//24209618//24981863//22575960//22608085 chr12:68051744-68051745(+) m6A CDS       24284625//24209618//24981863//22575960//22608085 chr12:68051972-68051973(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr12:68051994-68051995(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr12:68052018-68052019(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr12:68052144-68052145(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr12:68052225-68052226(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr12:68052411-68052412(+) m6A CDS       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr12:68052418-68052419(+) m6A CDS       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr12:68052466-68052467(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr12:68052480-68052481(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr12:68052570-68052571(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085 chr12:68052672-68052673(+) m6A 3'UTR       24284625//24981863//22608085 chr12:68052702-68052703(+) m6A 3'UTR       24284625 chr12:68052822-68052823(+) m6A 3'UTR       24284625 chr12:68053048-68053049(+) m6A 3'UTR       24981863

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	DYRK2	Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Nucleolus K562 cells     - Nucleus HCC cell line (HepG2)     - Ribosome HEK-293 cells     22199352

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	hiv1-miR-TAR-3p	l-685,458       5479543 Pha-665752       10461815

Interaction Network (The top 100 interactions):

Interactor1: hiv1-miR-TAR-3p
Interactor2: DYRK2

Evidence Support:

Prediction-Evidence	miRanda//Targetscan
Support Database	VmiReg