Basic Information:

  VIRBase ID:  

VHID00701416

  Virus:  

Human immunodeficiency virus 1 (HIV-1)

  Host:  

Homo sapiens

  Confidence Score:  

0.2455

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hiv1-miR-TAR-3p:  MIMAT0006017          CCND2:  NM_001759     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hiv1-miR-TAR-3p	CCND2
miRBase Accession/Entrez ID	MIMAT0006017	894
Organism	Human immunodeficiency virus 1 (HIV-1)	Homo sapiens
Category	miRNA	mRNA
Alias	-	KIAK0002//MPPH3

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	CCND2	chr12:4407683(+) A-I      intronic chr12:4406504(+) A-I      intronic chr12:4408273(+) A-I      intronic chr12:4408319(+) A-I      intronic chr12:4407661(+) A-I      intronic chr12:4408272(+) A-I      intronic chr12:4406535(+) A-I      intronic chr12:4408325(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	CCND2	chr12:4406341(+) A-T intron -    22484847 chr12:4406592(+) C-T intron -    22484847 chr12:4406734(+) C-T intron -    22484847 chr12:4406735(+) T-C intron -    22484847 chr12:4406736(+) C-A intron -    22484847 chr12:4407661(+) A-G intron -    22484847 chr12:4404682(+) T-C intron -    22484847 chr12:4408272(+) A-G intron -    22484847 chr12:4408273(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	CCND2	chr12:4382959-4382960(+) m6A 5'UTR       25456834//24981863 chr12:4382977-4382978(+) m6A 5'UTR       25456834//24981863 chr12:4383080-4383081(+) m6A 5'UTR       25456834//24981863 chr12:4383140-4383141(+) m6A 5'UTR       24981863 chr12:4383146-4383147(+) m6A 5'UTR       - chr12:4383154-4383155(+) m6A 5'UTR       - chr12:4409504-4409505(+) m6A 3'UTR       22608085 chr12:4409518-4409519(+) m6A 3'UTR       24981863//22608085 chr12:4409578-4409579(+) m6A 3'UTR       24209618//24981863//22608085 chr12:4409622-4409623(+) m6A 3'UTR       24209618//24981863//22608085 chr12:4409650-4409651(+) m6A 3'UTR       24209618//24981863//22608085 chr12:4409673-4409674(+) m6A 3'UTR       24209618//24981863//22608085 chr12:4409694-4409695(+) m6A 3'UTR       24209618//24981863//22608085

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	CCND2	Chromatin K562 cells     - Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Membrane K562 cells     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Ribosome Colon cancer cells     24393600

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	hiv1-miR-TAR-3p	l-685,458       5479543 Pha-665752       10461815

Interaction Network (The top 100 interactions):

Interactor1: hiv1-miR-TAR-3p
Interactor2: CCND2

Evidence Support:

Prediction-Evidence	cRep//miRanda//PITA//Targetscan
Support Database	RepTar//VmiReg