Basic Information:

  VIRBase ID:  

VHID00701029

  Virus:  

Human immunodeficiency virus 1 (HIV-1)

  Host:  

Homo sapiens

  Confidence Score:  

0.2483

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hiv1-miR-TAR-5p:  MIMAT0006016          LIN28B:  NM_001004317     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hiv1-miR-TAR-5p	LIN28B
miRBase Accession/Entrez ID	MIMAT0006016	389421
Organism	Human immunodeficiency virus 1 (HIV-1)	Homo sapiens
Category	miRNA	mRNA
Alias	-	CSDD2

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	LIN28B	chr6:105413340(+) A-I      intronic chr6:105491221(+) A-I      intronic chr6:105422319(+) A-I      intronic chr6:105461555(+) A-I      intronic chr6:105491218(+) A-I      intronic chr6:105516910(+) A-I      intronic chr6:105422824(+) A-I      intronic chr6:105431516(+) A-I      intronic chr6:105440432(+) A-I      intronic chr6:105459300(+) A-I      intronic chr6:105460954(+) A-I      intronic chr6:105422104(+) A-I      intronic chr6:105479617(+) A-I      intronic chr6:105415335(+) A-I      intronic chr6:105415296(+) A-I      intronic chr6:105422243(+) A-I      intronic chr6:105491160(+) A-I      intronic chr6:105466973(+) A-I      intronic chr6:105480531(+) A-I      intronic chr6:105422212(+) A-I      intronic chr6:105422208(+) A-I      intronic chr6:105454280(+) A-I      intronic chr6:105525024(+) A-I      intronic chr6:105427248(+) A-I      intronic chr6:105455549(+) A-I      intronic chr6:105444969(+) A-I      intronic chr6:105445035(+) A-I      intronic chr6:105466028(+) A-I      intronic chr6:105422188(+) A-I      intronic

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	LIN28B	chr6:105404957-105404958(+) m6A 5'UTR       24981863//22608085 chr6:105405003-105405004(+) m6A 5'UTR       24981863//22608085 chr6:105474276-105474277(+) m6A CDS       24981863//27773535 chr6:105474312-105474313(+) m6A CDS       24981863//27773535 chr6:105474325-105474326(+) m6A CDS       24981863//27773535 chr6:105526392-105526393(+) m6A CDS       25456834//24981863//22608085 chr6:105526441-105526442(+) m6A CDS       25456834//24981863//27773535//22608085 chr6:105526652-105526653(+) m6A CDS       25456834//24981863//27773535//22608085 chr6:105526724-105526725(+) m6A 3'UTR       24981863//22608085 chr6:105526775-105526776(+) m6A 3'UTR       24981863 chr6:105526791-105526792(+) m6A 3'UTR       24981863 chr6:105528694-105528695(+) m6A 3'UTR       27773535 chr6:105528725-105528726(+) m6A 3'UTR       24981863//27773535 chr6:105528764-105528765(+) m6A 3'UTR       24981863//27773535 chr6:105528777-105528778(+) m6A 3'UTR       24981863//27773535 chr6:105528835-105528836(+) m6A 3'UTR       27773535 chr6:105528845-105528846(+) m6A 3'UTR       27773535 chr6:105528895-105528896(+) m6A 3'UTR       27773535 chr6:105528900-105528901(+) m6A 3'UTR       27773535 chr6:105529390-105529391(+) m6A 3'UTR       27773535 chr6:105529442-105529443(+) m6A 3'UTR       27773535 chr6:105529490-105529491(+) m6A 3'UTR       27773535 chr6:105530982-105530983(+) m6A 3'UTR       27773535 chr6:105530990-105530991(+) m6A 3'UTR       27773535 chr6:105531008-105531009(+) m6A 3'UTR       27773535 chr6:105531038-105531039(+) Y 3'UTR       26075521 chr6:105531065-105531066(+) m6A 3'UTR       27773535

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	LIN28B	Chromatin K562 cells     - Cytosol HCC cell line (HepG2)     - Exosome Blood     - Insoluble cytoplasm HCC cell line (HepG2)     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus HCC cell line (HepG2)|K562 cells     -

Interaction Network (The top 100 interactions):

Interactor1: hiv1-miR-TAR-5p
Interactor2: LIN28B

Evidence Support:

Prediction-Evidence	cRep//miRanda//PITA//Rep//Targetscan
Support Database	RepTar//VmiReg