Basic Information:

  VIRBase ID:  

VHID00699955

  Virus:  

Human immunodeficiency virus 1 (HIV-1)

  Host:  

Homo sapiens

  Confidence Score:  

0.2455

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hiv1-miR-TAR-5p:  MIMAT0006016          EAF1:  NM_033083     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hiv1-miR-TAR-5p	EAF1
miRBase Accession/Entrez ID	MIMAT0006016	85403
Organism	Human immunodeficiency virus 1 (HIV-1)	Homo sapiens
Category	miRNA	mRNA
Alias	-	-

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	EAF1	chr3:15478503(+) A-I      intronic chr3:15483105(+) A-I      3'UTR chr3:15483094(+) A-I      3'UTR chr3:15483134(+) A-I      3'UTR

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	EAF1	chr3:15469049-15469050(+) m6A 5'UTR       24981863 chr3:15469131-15469132(+) m6A 5'UTR       24981863 chr3:15469143-15469144(+) m6A 5'UTR       24284625//24981863 chr3:15469295-15469296(+) m6A CDS       - chr3:15469302-15469303(+) m6A CDS       - chr3:15469314-15469315(+) m6A CDS       - chr3:15469324-15469325(+) m6A CDS       - chr3:15473725-15473726(+) m6A CDS//intron       24981863 chr3:15475890-15475891(+) m6A 3'UTR//CDS       24981863//27773535 chr3:15475980-15475981(+) m6A 3'UTR//CDS       24981863//27773535 chr3:15475987-15475988(+) m6A 3'UTR//CDS       24981863//27773535 chr3:15476019-15476020(+) m6A 3'UTR//CDS       24981863//27773535 chr3:15477876-15477877(+) m6A 3'UTR//CDS       27773535 chr3:15477911-15477912(+) m6A 3'UTR//CDS       - chr3:15477965-15477966(+) m6A 3'UTR//CDS       24209618//24981863 chr3:15478039-15478040(+) m6A 3'UTR//CDS       24284625//24209618//24981863//22608085 chr3:15478073-15478074(+) m6A 3'UTR//CDS       24284625//24209618//24981863//22608085 chr3:15480678-15480679(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085 chr3:15480698-15480699(+) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//22608085 chr3:15480710-15480711(+) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//22608085 chr3:15480792-15480793(+) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//22608085 chr3:15480854-15480855(+) m6A 3'UTR       24209618//25456834//24981863//27773535//22608085 chr3:15480882-15480883(+) m6A 3'UTR       24209618//24981863//22608085 chr3:15483144-15483145(+) m6A 3'UTR//intron       25456834 chr3:15483167-15483168(+) m6A 3'UTR//intron       25456834//22608085 chr3:15483209-15483210(+) m6A 3'UTR//intron       25456834//22608085 chr3:15483251-15483252(+) m6A 3'UTR//intron       25456834//22608085 chr3:15483294-15483295(+) m6A 3'UTR//intron       25456834//22608085 chr3:15483324-15483325(+) m6A 3'UTR//intron       25456834 chr3:15483334-15483335(+) m6A 3'UTR//intron       25456834 chr3:15483857-15483858(+) m6A 3'UTR//intron       27773535 chr3:15483885-15483886(+) m6A 3'UTR//intron       27773535 chr3:15483890-15483891(+) m6A 3'UTR//intron       27773535

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	EAF1	Exosome Blood     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus HCC cell line (HepG2)|K562 cells     - Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: hiv1-miR-TAR-5p
Interactor2: EAF1

Evidence Support:

Prediction-Evidence	cRep//miRanda//PITA//Targetscan
Support Database	RepTar//VmiReg