Detail Information

Basic Information:


  VIRBase ID:  

VHID00698663

  Virus:  

Human immunodeficiency virus 1 (HIV-1)

  Host:  

Homo sapiens

  Confidence Score:  

0.2202

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hiv1-miR-TAR-5p:           IRAK4:      

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Interactor Information:


Interactor1 Interactor2
Symbol hiv1-miR-TAR-5p IRAK4
miRBase
Accession/Entrez ID		 MIMAT0006016 51135
Organism Human immunodeficiency virus 1 (HIV-1) Homo sapiens
Category miRNA mRNA
Alias - IMD67//IPD1//IRAK-4//NY-REN-64//REN64

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR IRAK4
chr12:44153234(+) A-I      intronic
chr12:44171117(+) A-I      intronic
chr12:44168237(+) A-I      intronic
chr12:44171152(+) A-I      intronic
chr12:44168127(+) A-I      intronic
chr12:44163284(+) A-I      intronic
chr12:44168109(+) A-I      intronic
chr12:44163226(+) A-I      intronic
chr12:44171065(+) A-I      intronic
chr12:44168257(+) A-I      intronic
chr12:44168302(+) A-I      intronic
chr12:44171012(+) A-I      intronic
chr12:44171107(+) A-I      intronic
chr12:44182586(+) A-I      3'UTR
chr12:44182479(+) A-I      3'UTR
chr12:44182529(+) A-I      3'UTR
chr12:44182460(+) A-I      3'UTR
chr12:44181631(+) A-I      3'UTR
chr12:44182417(+) A-I      3'UTR
chr12:44182407(+) A-I      3'UTR
chr12:44181695(+) A-I      3'UTR
chr12:44182520(+) A-I      3'UTR
chr12:44182423(+) A-I      3'UTR
chr12:44182404(+) A-I      3'UTR
chr12:44182362(+) A-I      3'UTR
chr12:44181659(+) A-I      3'UTR
chr12:44181682(+) A-I      3'UTR
chr12:44181830(+) A-I      3'UTR
chr12:44181810(+) A-I      3'UTR
chr12:44181713(+) A-I      3'UTR
chr12:44181650(+) A-I      3'UTR
chr12:44182555(+) A-I      3'UTR
chr12:44181604(+) A-I      3'UTR
chr12:44181709(+) A-I      3'UTR
chr12:44181698(+) A-I      3'UTR
chr12:44182472(+) A-I      3'UTR
chr12:44181603(+) A-I      3'UTR
chr12:44182509(+) A-I      3'UTR
chr12:44181583(+) A-I      3'UTR
chr12:44182575(+) A-I      3'UTR
chr12:44182558(+) A-I      3'UTR
chr12:44168213(+) A-I      intronic
chr12:44170932(+) A-I      intronic
chr12:44177145(+) A-I      intronic
chr12:44171149(+) A-I      intronic
chr12:44169824(+) A-I      intronic
chr12:44171071(+) A-I      intronic
chr12:44171081(+) A-I      intronic
chr12:44153676(+) A-I      intronic
chr12:44171112(+) A-I      intronic
chr12:44181766(+) A-I      3'UTR
chr12:44181673(+) A-I      3'UTR
chr12:44181801(+) A-I      3'UTR
chr12:44181674(+) A-I      3'UTR
chr12:44181605(+) A-I      3'UTR
chr12:44181684(+) A-I      3'UTR
chr12:44181812(+) A-I      3'UTR
chr12:44181597(+) A-I      3'UTR
chr12:44181683(+) A-I      3'UTR
chr12:44181710(+) A-I      3'UTR
chr12:44182551(+) A-I      3'UTR
chr12:44182526(+) A-I      3'UTR
chr12:44181749(+) A-I      3'UTR
chr12:44181781(+) A-I      3'UTR
chr12:44182611(+) A-I      3'UTR
chr12:44181651(+) A-I      3'UTR
chr12:44181784(+) A-I      3'UTR
chr12:44182543(+) A-I      3'UTR
chr12:44181739(+) A-I      3'UTR
chr12:44182447(+) A-I      3'UTR
chr12:44181310(+) A-I      3'UTR
chr12:44181435(+) A-I      3'UTR
chr12:44181774(+) A-I      3'UTR
chr12:44181745(+) A-I      3'UTR
chr12:44181610(+) A-I      3'UTR
chr12:44182482(+) A-I      3'UTR
chr12:44181805(+) A-I      3'UTR
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED IRAK4
chr12:44181631(+) A-I exon 3'UTR    15258596
chr12:44181674(+) A-I exon 3'UTR    15258596
chr12:44181739(+) A-I exon 3'UTR    15258596   //21960545   //22327324
chr12:44181749(+) A-I exon 3'UTR    15258596   //21960545   //22327324
chr12:44181605(+) A-I intron -    22327324
chr12:44181745(+) A-I intron -    21960545
chr12:44181774(+) A-I intron -    21960545
chr12:44182543(+) A-I intron -    21960545
chr12:44182551(+) A-G intron -    21725310   //22484847
chr12:44153675(+) G-A intron -    22484847
chr12:44181651(+) A-G intron -    22484847
chr12:44181673(+) A-G intron -    22484847
chr12:44181674(+) A-G intron -    22484847
chr12:44181739(+) A-G intron -    22484847
chr12:44181745(+) A-G intron -    22484847
chr12:44181749(+) A-G intron -    22484847
chr12:44181774(+) A-G intron -    22484847
chr12:44181805(+) A-G intron -    22484847
chr12:44181812(+) A-G intron -    22484847
chr12:44181879(+) T-C intron -    22484847
chr12:44182447(+) A-G intron -    22484847
chr12:44182472(+) A-G intron -    22484847
chr12:44182526(+) A-G intron -    22484847
chr12:44182558(+) A-G intron -    22484847
chr12:44171071(+) A-G intron -    22484847
chr12:44171081(+) A-G intron -    22484847
chr12:44171107(+) A-G intron -    22484847
chr12:44181605(+) A-G intron -    22484847
chr12:44181683(+) A-G intron -    22484847
chr12:44181684(+) A-G intron -    22484847
chr12:44181801(+) A-G intron -    22484847
chr12:44182482(+) A-G intron -    22484847
chr12:44182543(+) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase IRAK4
chr12:44152997-44152998(+) m6A 5'UTR//intron       25456834
chr12:44153094-44153095(+) m6A 5'UTR//intron       25456834
chr12:44153133-44153134(+) m6A 5'UTR//intron       25456834
chr12:44180519-44180520(+) m6A 3'UTR       24981863
chr12:44180534-44180535(+) m6A 3'UTR       24981863
chr12:44180634-44180635(+) m6A 3'UTR       24981863
chr12:44180660-44180661(+) m6A 3'UTR       24981863
chr12:44180770-44180771(+) m6A 3'UTR       24981863
chr12:44181200-44181201(+) m6A 3'UTR       22608085
chr12:44181215-44181216(+) m6A 3'UTR       22608085
chr12:44181246-44181247(+) m6A 3'UTR       22608085
chr12:44181312-44181313(+) m6A 3'UTR       24981863//22608085
chr12:44181339-44181340(+) m6A 3'UTR       24981863//22608085
chr12:44181381-44181382(+) m6A 3'UTR       24981863//22608085
chr12:44181403-44181404(+) m6A 3'UTR       24981863//22608085
chr12:44181537-44181538(+) m6A 3'UTR       24981863//22608085
chr12:44181553-44181554(+) m6A 3'UTR       24981863//22608085
chr12:44181660-44181661(+) m6A 3'UTR       24981863
chr12:44181683-44181684(+) m6A 3'UTR       -
chr12:44181730-44181731(+) m6A 3'UTR       24981863
chr12:44181770-44181771(+) m6A 3'UTR       24981863
chr12:44181780-44181781(+) m6A 3'UTR       24981863
chr12:44182813-44182814(+) m6A 3'UTR       24981863
chr12:44182820-44182821(+) m6A 3'UTR       24981863
chr12:44182849-44182850(+) m6A 3'UTR       24981863
chr12:44182889-44182890(+) m6A 3'UTR       24981863

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate IRAK4
Cytosol K562 cells     -
Exosome Blood     -
Nucleoplasm K562 cells     -
Ribosome-free cytosol Colon cancer cells     24393600

Interaction Network (The top 100 interactions):


Interactor1: hiv1-miR-TAR-5p
Interactor2: IRAK4

Evidence Support:


Prediction-Evidence miRanda//PITA
Support Database VmiReg

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