Basic Information:

  VIRBase ID:  

VHID00695928

  Virus:  

Human immunodeficiency virus 1 (HIV-1)

  Host:  

Homo sapiens

  Confidence Score:  

0.2202

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hiv1-miR-TAR-5p:  MIMAT0006016          ACO1:  NM_001278352     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hiv1-miR-TAR-5p	ACO1
miRBase Accession/Entrez ID	MIMAT0006016	48
Organism	Human immunodeficiency virus 1 (HIV-1)	Homo sapiens
Category	miRNA	mRNA
Alias	-	ACONS//HEL60//IREB1//IREBP//IREBP1//IRP1

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	ACO1	chr9:32389931(+) A-I      intronic chr9:32390076(+) A-I      intronic chr9:32409594(+) A-I      intronic chr9:32409620(+) A-I      intronic chr9:32411971(+) A-I      intronic chr9:32413386(+) A-I      intronic chr9:32413388(+) A-I      intronic chr9:32413394(+) A-I      intronic chr9:32413884(+) A-I      intronic chr9:32413960(+) A-I      intronic chr9:32414000(+) A-I      intronic chr9:32414016(+) A-I      intronic chr9:32414092(+) A-I      intronic chr9:32416193(+) A-I      intronic chr9:32416186(+) A-I      intronic chr9:32416167(+) A-I      intronic chr9:32413892(+) A-I      intronic chr9:32413361(+) A-I      intronic chr9:32411984(+) A-I      intronic chr9:32409593(+) A-I      intronic chr9:32416365(+) A-I      intronic chr9:32409767(+) A-I      intronic chr9:32409758(+) A-I      intronic chr9:32411972(+) A-I      intronic chr9:32414026(+) A-I      intronic chr9:32409705(+) A-I      intronic chr9:32410467(+) A-I      intronic chr9:32411975(+) A-I      intronic

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	ACO1	chr9:32384655-32384656(+) m6A 5'UTR       24284625//24981863 chr9:32419084-32419085(+) Y CDS       26075521 chr9:32430449-32430450(+) m6A CDS       - chr9:32430538-32430539(+) m6A CDS       - chr9:32450267-32450268(+) m6A 3'UTR       27773535 chr9:32450368-32450369(+) m6A 3'UTR       27773535 chr9:32452444-32452445(+) m6A 3'UTR       - chr9:32452491-32452492(+) m6A 3'UTR       - chr9:32452497-32452498(+) m6A 3'UTR       - chr9:32452511-32452512(+) m6A 3'UTR       -

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	ACO1	Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Ribosome HEK-293 cells     22199352

Interaction Network (The top 100 interactions):

Interactor1: hiv1-miR-TAR-5p
Interactor2: ACO1

Evidence Support:

Prediction-Evidence	miRanda//Targetscan
Support Database	VmiReg