Basic Information:

  VIRBase ID:  

VHID00694128

  Virus:  

Human immunodeficiency virus 1 (HIV-1)

  Host:  

Homo sapiens

  Confidence Score:  

0.2202

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hiv1-miR-H1:  MIMAT0004480          WFDC8:  NM_130896     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hiv1-miR-H1	WFDC8
miRBase Accession/Entrez ID	MIMAT0004480	90199
Organism	Human immunodeficiency virus 1 (HIV-1)	Homo sapiens
Category	miRNA	mRNA
Alias	-	C20orf170//dJ461P17.1//HEL-S-292//WAP8

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	WFDC8	chr20:44180010(-) A-I      3'UTR chr20:44180075(-) A-I      3'UTR chr20:44180119(-) A-I      3'UTR chr20:44180185(-) A-I      3'UTR chr20:44180186(-) A-I      3'UTR chr20:44180211(-) A-I      3'UTR chr20:44180146(-) A-I      3'UTR chr20:44180101(-) A-I      3'UTR chr20:44180110(-) A-I      3'UTR chr20:44207634(-) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	WFDC8	chr20:44180074(-) A-I exon 3'UTR    15342557 chr20:44180101(-) A-I exon 3'UTR    15342557 chr20:44180110(-) A-I exon 3'UTR    15342557 chr20:44180146(-) A-I exon 3'UTR    15342557 chr20:44180168(-) A-I exon 3'UTR    15342557 chr20:44184375(-) A-I exon CDS    15342557

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hiv1-miR-H1	Exosome Jurkat-derived T cell line (J77cl20)     21505438
	WFDC8	Cytoplasm Nasopharyngeal carcinoma cells     20498841 Exosome Blood     - Nucleus Nasopharyngeal carcinoma cells     20498841

Interaction Network (The top 100 interactions):

Interactor1: hiv1-miR-H1
Interactor2: WFDC8

Evidence Support:

Prediction-Evidence	cRep//RNAHybrid
Support Database	RepTar//VmiReg