Basic Information:

  VIRBase ID:  

VHID00693748

  Virus:  

Human immunodeficiency virus 1 (HIV-1)

  Host:  

Homo sapiens

  Confidence Score:  

0.2494

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hiv1-miR-H1:  MIMAT0004480          CCNL2:  NR_146722     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hiv1-miR-H1	CCNL2
miRBase Accession/Entrez ID	MIMAT0004480	81669
Organism	Human immunodeficiency virus 1 (HIV-1)	Homo sapiens
Category	miRNA	mRNA
Alias	-	ANIA-6B//CCNM//CCNS//HCLA-ISO//HLA-ISO//PCEE//SB138

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	CCNL2	chr1:1331811(-) A-I      intronic chr1:1331374(-) A-I      intronic chr1:1331779(-) A-I      intronic chr1:1332309(-) A-I      intronic chr1:1333235(-) A-I      intronic chr1:1333039(-) A-I      intronic chr1:1333195(-) A-I      intronic chr1:1333162(-) A-I      intronic chr1:1331447(-) A-I      intronic chr1:1331394(-) A-I      intronic chr1:1331594(-) A-I      intronic chr1:1333188(-) A-I      intronic chr1:1332985(-) A-I      intronic chr1:1331459(-) A-I      intronic chr1:1331440(-) A-I      intronic chr1:1331421(-) A-I      intronic chr1:1332306(-) A-I      intronic chr1:1332399(-) A-I      intronic chr1:1331849(-) A-I      intronic chr1:1331840(-) A-I      intronic chr1:1332218(-) A-I      intronic chr1:1331921(-) A-I      intronic chr1:1333133(-) A-I      intronic chr1:1331878(-) A-I      intronic chr1:1331715(-) A-I      intronic chr1:1331437(-) A-I      intronic chr1:1331301(-) A-I      intronic chr1:1332767(-) A-I      intronic chr1:1332751(-) A-I      intronic chr1:1331628(-) A-I      intronic chr1:1331919(-) A-I      intronic chr1:1333185(-) A-I      intronic chr1:1332257(-) A-I      intronic chr1:1332026(-) A-I      intronic chr1:1333023(-) A-I      intronic chr1:1333145(-) A-I      intronic chr1:1332225(-) A-I      intronic chr1:1331744(-) A-I      intronic chr1:1332097(-) A-I      intronic chr1:1332534(-) A-I      intronic chr1:1332470(-) A-I      intronic chr1:1331314(-) A-I      intronic chr1:1331988(-) A-I      intronic chr1:1331365(-) A-I      intronic chr1:1333123(-) A-I      intronic chr1:1331340(-) A-I      intronic chr1:1332772(-) A-I      intronic chr1:1332056(-) A-I      intronic chr1:1331775(-) A-I      intronic chr1:1332304(-) A-I      intronic chr1:1330381(-) A-I      intronic chr1:1332330(-) A-I      intronic chr1:1332469(-) A-I      intronic chr1:1332400(-) A-I      intronic chr1:1332092(-) A-I      intronic chr1:1333075(-) A-I      intronic chr1:1332998(-) A-I      intronic chr1:1333169(-) A-I      intronic chr1:1333007(-) A-I      intronic chr1:1332322(-) A-I      intronic chr1:1331385(-) A-I      intronic chr1:1331814(-) A-I      intronic chr1:1331434(-) A-I      intronic chr1:1331785(-) A-I      intronic chr1:1332293(-) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	CCNL2	chr1:1324027(-) A-I intron -    21960545 chr1:1329482(-) T-C intron -    22484847 chr1:1329958(-) G-A intron -    22484847 chr1:1329959(-) T-C intron -    22484847 chr1:1330381(-) A-G intron -    22484847 chr1:1331340(-) A-G intron -    22484847 chr1:1331365(-) A-G intron -    22484847 chr1:1331434(-) A-G intron -    22484847 chr1:1331437(-) A-G intron -    22484847 chr1:1331715(-) A-G intron -    22484847 chr1:1332097(-) A-G intron -    22484847 chr1:1332257(-) A-G intron -    22484847 chr1:1332399(-) A-G intron -    22484847 chr1:1332400(-) A-G intron -    22484847 chr1:1332772(-) A-G intron -    22484847 chr1:1333023(-) A-G intron -    22484847 chr1:1333133(-) A-G intron -    22484847 chr1:1333185(-) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	CCNL2	chr1:1321103-1321104(-) m6A exon       27773535 chr1:1321166-1321167(-) m6A exon       27773535 chr1:1321201-1321202(-) m6A exon       27773535 chr1:1321276-1321277(-) m6A exon       24284625//27773535 chr1:1321285-1321286(-) m6A exon       24284625//27773535 chr1:1321306-1321307(-) m6A exon       24284625//27773535 chr1:1321390-1321391(-) m6A exon       24284625//25456834//24981863//27773535//27371828//22608085 chr1:1321408-1321409(-) m6A exon       24284625//25456834//24981863//27773535//27371828//22608085 chr1:1321442-1321443(-) m6A exon       24284625//25456834//24981863//27773535//27371828//22608085 chr1:1321462-1321463(-) m6A exon       24284625//25456834//24981863//27773535//27371828//22608085 chr1:1321541-1321542(-) m6A exon       24284625//25456834//24981863//27773535//27371828//22608085 chr1:1321593-1321594(-) m6A exon       24284625//25456834//24981863//27371828//22608085 chr1:1321632-1321633(-) m6A exon       24284625//24981863//22608085 chr1:1321874-1321875(-) m6A 3'UTR//exon       27773535 chr1:1321895-1321896(-) m6A 3'UTR//exon       27773535 chr1:1322041-1322042(-) m6A 3'UTR//exon       27773535 chr1:1322063-1322064(-) m6A 3'UTR//exon       24284625//27773535 chr1:1322070-1322071(-) m6A 3'UTR//exon       24284625//27773535 chr1:1322106-1322107(-) m6A 3'UTR//exon       24284625//27773535 chr1:1322208-1322209(-) m6A 3'UTR//exon       24284625//24209618//27773535 chr1:1322264-1322265(-) Y 3'UTR//exon       26075521 chr1:1322403-1322404(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085 chr1:1322423-1322424(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085 chr1:1322431-1322432(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085 chr1:1322454-1322455(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085 chr1:1322487-1322488(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085 chr1:1322641-1322642(-) m6A 3'UTR//CDS//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085 chr1:1322679-1322680(-) Gm 3'UTR//CDS//exon       - chr1:1322821-1322822(-) m6A 3'UTR//CDS//exon       24284625//24209618//24981863//27773535//27371828//22575960//22608085 chr1:1322883-1322884(-) m6A 3'UTR//CDS//exon       24284625//24981863//27773535//27371828//27773536 chr1:1323348-1323349(-) m6A 3'UTR//CDS//exon       24284625//24981863//27773535//27371828//27773536 chr1:1323390-1323391(-) m6A 3'UTR//CDS//exon       24284625//24981863//27773535//27371828//27773536 chr1:1323461-1323462(-) Y exon//intron       25192136 chr1:1323505-1323506(-) m6A exon//intron       27773535//27773536 chr1:1326598-1326599(-) m6A 3'UTR//exon//intron       24284625//24981863//27773535//22575960//22608085 chr1:1326738-1326739(-) m6A 3'UTR//exon//intron       24284625//25456834//24981863//27773536//22575960 chr1:1326814-1326815(-) m6A 3'UTR//exon//intron       24284625//25456834//24981863//27773536//22575960 chr1:1326936-1326937(-) m6A CDS//exon//intron       25456834 chr1:1326954-1326955(-) m6A CDS//exon//intron       25456834 chr1:1327430-1327431(-) m6A exon//intron       24981863 chr1:1333618-1333619(-) m6A CDS//exon       27773535 chr1:1334302-1334303(-) m6A 5'UTR//intron       27773536 chr1:1334463-1334464(-) m6A CDS//exon       27773536 chr1:1334534-1334535(-) m6A CDS//exon       27371828//27773536 chr1:1334570-1334571(-) m6A CDS//exon       27371828//27773536

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hiv1-miR-H1	Exosome Jurkat-derived T cell line (J77cl20)     21505438
	CCNL2	Chromatin K562 cells     - Cytosol K562 cells     - Exosome Blood     - Membrane HCC cell line (HepG2)|K562 cells     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus Colon cancer cells     24393600 Nucleus HeLa-S3 cells|K562 cells     -

Interaction Network (The top 100 interactions):

Interactor1: hiv1-miR-H1
Interactor2: CCNL2

Evidence Support:

Prediction-Evidence	cRep//miRanda//PITA//Rep//RNAHybrid//Targetscan
Support Database	RepTar//VmiReg