Basic Information:

  VIRBase ID:  

VHID00693666

  Virus:  

Human immunodeficiency virus 1 (HIV-1)

  Host:  

Homo sapiens

  Confidence Score:  

0.2494

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hiv1-miR-H1:  MIMAT0004480          CD276:  NM_025240     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hiv1-miR-H1	CD276
miRBase Accession/Entrez ID	MIMAT0004480	80381
Organism	Human immunodeficiency virus 1 (HIV-1)	Homo sapiens
Category	miRNA	mRNA
Alias	-	4Ig-B7-H3//B7-H3//B7H3//B7RP-2

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	CD276	chr15:73983262(+) A-I      intronic chr15:73987276(+) A-I      intronic chr15:73987237(+) A-I      intronic chr15:73987220(+) A-I      intronic

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	CD276	chr15:73976698-73976699(+) m6A 5'UTR//intron       25456834//24981863 chr15:74000788-74000789(+) m6A 3'UTR//CDS//exon       24284625 chr15:74001997-74001998(+) m6A 3'UTR//CDS//exon       25456834//24981863 chr15:74002026-74002027(+) m6A 3'UTR//CDS//exon       25456834//24981863 chr15:74003491-74003492(+) m6A 3'UTR//CDS//exon       25456834//24981863 chr15:74003517-74003518(+) m6A CDS//intron       25456834//24981863 chr15:74005281-74005282(+) m6A 3'UTR//CDS//exon       24284625 chr15:74005305-74005306(+) m6A 3'UTR//exon       24284625 chr15:74005437-74005438(+) m6A 3'UTR//exon//intron       24284625//24209618//24981863//22608085 chr15:74005466-74005467(+) m6A 3'UTR//exon//intron       24284625//24209618//24981863//27773535//22608085 chr15:74005506-74005507(+) m6A 3'UTR//exon//intron       24284625//24209618//24981863//27773535//22608085 chr15:74005515-74005516(+) m6A 3'UTR//exon//intron       24284625//24209618//24981863//27773535//22608085 chr15:74005591-74005592(+) m6A 3'UTR//exon//intron       24284625//24209618//24981863//27773535//22575960//22608085 chr15:74005640-74005641(+) m6A 3'UTR//exon//intron       24284625//24209618//24981863//27773535//22608085 chr15:74005682-74005683(+) m6A 3'UTR//exon//intron       24284625//24209618//24981863//22608085 chr15:74005714-74005715(+) m6A 3'UTR//exon//intron       24284625//24209618//24981863//22608085 chr15:74005816-74005817(+) m6A 3'UTR//exon//intron       24284625//24209618 chr15:74005822-74005823(+) m6A 3'UTR//exon//intron       24284625//24209618 chr15:74005932-74005933(+) m6A 3'UTR//exon//intron       24284625 chr15:74005975-74005976(+) m6A 3'UTR//exon//intron       24284625 chr15:74005997-74005998(+) m6A 3'UTR//exon//intron       24284625 chr15:74006438-74006439(+) m6A 3'UTR//exon       24284625//25456834 chr15:74006452-74006453(+) m6A 3'UTR//exon       24284625//25456834//24981863//22575960 chr15:74006542-74006543(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr15:74006604-74006605(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr15:74006615-74006616(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr15:74006709-74006710(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr15:74006774-74006775(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//27773535//22608085 chr15:74006794-74006795(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//27773535//22608085 chr15:74006813-74006814(+) m6A 3'UTR//exon       24284625//25456834//24981863//27773535//22608085

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hiv1-miR-H1	Exosome Jurkat-derived T cell line (J77cl20)     21505438
	CD276	Exosome Blood     - Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: hiv1-miR-H1
Interactor2: CD276

Evidence Support:

Prediction-Evidence	cRep//miRanda//PITA//Rep//RNAHybrid//Targetscan
Support Database	RepTar//VmiReg