Basic Information:

  VIRBase ID:  

VHID00693046

  Virus:  

Human immunodeficiency virus 1 (HIV-1)

  Host:  

Homo sapiens

  Confidence Score:  

0.2381

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hiv1-miR-H1:  MIMAT0004480          ISLR2:  NM_001130136     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hiv1-miR-H1	ISLR2
miRBase Accession/Entrez ID	MIMAT0004480	57611
Organism	Human immunodeficiency virus 1 (HIV-1)	Homo sapiens
Category	miRNA	mRNA
Alias	-	LINX

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	ISLR2	chr15:74426028-74426029(+) m6A CDS//intron       25456834 chr15:74426231-74426232(+) m6A CDS//intron       25456834 chr15:74426255-74426256(+) m6A CDS//intron       25456834 chr15:74426264-74426265(+) m6A CDS//intron       25456834 chr15:74426330-74426331(+) m6A CDS//intron       25456834 chr15:74426385-74426386(+) m6A CDS//intron       25456834 chr15:74426407-74426408(+) m6A CDS//intron       25456834 chr15:74426434-74426435(+) m6A CDS//intron       25456834 chr15:74426449-74426450(+) m6A CDS//intron       25456834 chr15:74426482-74426483(+) m6A CDS//intron       25456834 chr15:74427025-74427026(+) m6A CDS//intron       25456834 chr15:74427148-74427149(+) m6A CDS//intron       25456834 chr15:74427160-74427161(+) m6A CDS//intron       25456834 chr15:74428599-74428600(+) m6A 3'UTR//intron       25456834

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hiv1-miR-H1	Exosome Jurkat-derived T cell line (J77cl20)     21505438
	ISLR2	Cytoplasm Nasopharyngeal carcinoma cells     20498841 Cytoplasm Nasopharyngeal carcinoma cells     20498841 Cytoplasm Nasopharyngeal carcinoma cells     20498841 Cytoplasm Nasopharyngeal carcinoma cells     20498841 Exosome Blood     - Nucleus Nasopharyngeal carcinoma cells     20498841 Nucleus Nasopharyngeal carcinoma cells     20498841 Nucleus Nasopharyngeal carcinoma cells     20498841 Nucleus Nasopharyngeal carcinoma cells     20498841

Interaction Network (The top 100 interactions):

Interactor1: hiv1-miR-H1
Interactor2: ISLR2

Evidence Support:

Prediction-Evidence	miRanda//RNAHybrid//Targetscan
Support Database	VmiReg