Basic Information:

  VIRBase ID:  

VHID00692561

  Virus:  

Human immunodeficiency virus 1 (HIV-1)

  Host:  

Homo sapiens

  Confidence Score:  

0.2381

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hiv1-miR-H1:  MIMAT0004480          TMEM33:  NM_018126     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hiv1-miR-H1	TMEM33
miRBase Accession/Entrez ID	MIMAT0004480	55161
Organism	Human immunodeficiency virus 1 (HIV-1)	Homo sapiens
Category	miRNA	mRNA
Alias	-	1600019D15Rik//Pom33//SHINC-3//SHINC3

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	TMEM33	chr4:41945280(+) A-I      intronic chr4:41942137(+) A-I      intronic chr4:41945467(+) A-I      intronic chr4:41960287(+) A-I      3'UTR chr4:41958203(+) A-I      3'UTR chr4:41945422(+) A-I      intronic chr4:41942149(+) A-I      intronic chr4:41942705(+) A-I      intronic chr4:41942151(+) A-I      intronic chr4:41958095(+) A-I      3'UTR chr4:41958134(+) A-I      3'UTR chr4:41960913(+) A-I      3'UTR chr4:41958292(+) A-I      3'UTR chr4:41960288(+) A-I      3'UTR chr4:41958158(+) A-I      3'UTR chr4:41945421(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	TMEM33	chr4:41942705(+) A-I intron -    22327324 chr4:41942687(+) A-G intron -    22484847 chr4:41942705(+) A-G intron -    22484847 chr4:41945421(+) A-G intron -    22484847 chr4:41945422(+) A-G intron -    22484847 chr4:41960865(+) A-T intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	TMEM33	chr4:41937248-41937249(+) m6A 5'UTR       24284625//24981863 chr4:41937275-41937276(+) m6A 5'UTR       24284625//24981863//22575960 chr4:41937336-41937337(+) m6A 5'UTR//intron       22575960

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hiv1-miR-H1	Exosome Jurkat-derived T cell line (J77cl20)     21505438
	TMEM33	Exosome Blood     - Nucleoplasm K562 cells     - Nucleus HeLa-S3 cells     - Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: hiv1-miR-H1
Interactor2: TMEM33

Evidence Support:

Prediction-Evidence	miRanda//PITA//Targetscan
Support Database	VmiReg