Basic Information:

  VIRBase ID:  

VHID00690711

  Virus:  

Human immunodeficiency virus 1 (HIV-1)

  Host:  

Homo sapiens

  Confidence Score:  

0.2455

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hiv1-miR-H1:  MIMAT0004480          BZW1:  NM_014670     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hiv1-miR-H1	BZW1
miRBase Accession/Entrez ID	MIMAT0004480	9689
Organism	Human immunodeficiency virus 1 (HIV-1)	Homo sapiens
Category	miRNA	mRNA
Alias	-	BZAP45//Nbla10236

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	BZW1	chr2:201685214(+) A-I      intronic chr2:201683963(+) A-I      intronic chr2:201684032(+) A-I      intronic chr2:201683930(+) A-I      intronic chr2:201684533(+) A-I      intronic chr2:201686637(+) A-I      intronic chr2:201683860(+) A-I      intronic chr2:201686689(+) A-I      intronic chr2:201683859(+) A-I      intronic chr2:201683886(+) A-I      intronic chr2:201686538(+) A-I      intronic chr2:201686387(+) A-I      intronic chr2:201683928(+) A-I      intronic chr2:201686331(+) A-I      intronic chr2:201683861(+) A-I      intronic chr2:201684461(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	BZW1	chr2:201683844(+) A-G intron -    22484847 chr2:201683861(+) A-G intron -    22484847 chr2:201683886(+) A-G intron -    22484847 chr2:201684439(+) A-G intron -    22484847 chr2:201684442(+) A-G intron -    22484847 chr2:201684444(+) A-G intron -    22484847 chr2:201684461(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	BZW1	chr2:201676305-201676306(+) m6A 5'UTR//intron       24981863 chr2:201676333-201676334(+) m6A 5'UTR//intron       24981863 chr2:201676423-201676424(+) m6A 5'UTR//intron       24981863 chr2:201676445-201676446(+) m6A 5'UTR//intron       24981863 chr2:201676467-201676468(+) m6A 5'UTR//intron       - chr2:201676651-201676652(+) m6A 5'UTR//exon//intron       24284625//24981863//22608085 chr2:201677495-201677496(+) m1A 5'UTR//intron       26863196 chr2:201677991-201677992(+) m6A CDS//exon       24981863//22575960 chr2:201678036-201678037(+) m6A exon//intron       24981863//22575960 chr2:201678045-201678046(+) m6A exon//intron       22575960 chr2:201683085-201683086(+) m6A CDS//exon       24981863//27773535 chr2:201683511-201683512(+) m6A CDS//exon       24981863//27773535 chr2:201683577-201683578(+) m6A CDS//exon       24981863//27773535 chr2:201683632-201683633(+) m6A exon//intron       24981863 chr2:201683648-201683649(+) m6A exon//intron       24981863 chr2:201683682-201683683(+) m6A exon//intron       - chr2:201688380-201688381(+) m6A 3'UTR       27773535

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hiv1-miR-H1	Exosome Jurkat-derived T cell line (J77cl20)     21505438
	BZW1	Cytoplasm Nasopharyngeal carcinoma cells     20498841 Exosome Blood     - Membrane HCC cell line (HepG2)|K562 cells     - Nucleoplasm K562 cells     - Nucleus Nasopharyngeal carcinoma cells     20498841 Nucleus HCC cell line (HepG2)|K562 cells     - Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: hiv1-miR-H1
Interactor2: BZW1

Evidence Support:

Prediction-Evidence	cRep//miRanda//PITA//Targetscan
Support Database	RepTar//VmiReg