Basic Information:

  VIRBase ID:  

VHID00689514

  Virus:  

Human immunodeficiency virus 1 (HIV-1)

  Host:  

Homo sapiens

  Confidence Score:  

0.2455

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hiv1-miR-H1:  MIMAT0004480          POLB:  NM_002690     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hiv1-miR-H1	POLB
miRBase Accession/Entrez ID	MIMAT0004480	5423
Organism	Human immunodeficiency virus 1 (HIV-1)	Homo sapiens
Category	miRNA	mRNA
Alias	-	-

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	POLB	chr8:42215877(+) A-I      intronic chr8:42220869(+) A-I      intronic chr8:42215431(+) A-I      intronic chr8:42221011(+) A-I      intronic chr8:42223432(+) A-I      intronic chr8:42223419(+) A-I      intronic chr8:42223442(+) A-I      intronic chr8:42220996(+) A-I      intronic chr8:42221610(+) A-I      intronic chr8:42220958(+) A-I      intronic chr8:42220892(+) A-I      intronic chr8:42228698(+) A-I      intronic chr8:42228705(+) A-I      intronic chr8:42228771(+) A-I      intronic chr8:42222468(+) A-I      intronic chr8:42223371(+) A-I      intronic chr8:42220887(+) A-I      intronic chr8:42220880(+) A-I      intronic chr8:42220567(+) A-I      intronic chr8:42220868(+) A-I      intronic chr8:42220557(+) A-I      intronic chr8:42220552(+) A-I      intronic chr8:42220522(+) A-I      intronic chr8:42218363(+) A-I      intronic chr8:42217675(+) A-I      intronic chr8:42215941(+) A-I      intronic chr8:42201528(+) A-I      intronic chr8:42217663(+) A-I      intronic chr8:42217566(+) A-I      intronic chr8:42197324(+) A-I      intronic chr8:42200947(+) A-I      intronic chr8:42200956(+) A-I      intronic chr8:42200966(+) A-I      intronic chr8:42228787(+) A-I      intronic chr8:42220861(+) A-I      intronic chr8:42228783(+) A-I      intronic chr8:42215833(+) A-I      intronic chr8:42215803(+) A-I      intronic chr8:42201529(+) A-I      intronic chr8:42210383(+) A-I      intronic chr8:42215766(+) A-I      intronic chr8:42215486(+) A-I      intronic chr8:42215445(+) A-I      intronic chr8:42210600(+) A-I      intronic chr8:42212201(+) A-I      intronic chr8:42215362(+) A-I      intronic chr8:42221667(+) A-I      intronic chr8:42221466(+) A-I      intronic chr8:42210766(+) A-I      intronic chr8:42210768(+) A-I      intronic chr8:42201670(+) A-I      intronic chr8:42217749(+) A-I      intronic chr8:42221899(+) A-I      intronic chr8:42201668(+) A-I      intronic chr8:42210343(+) A-I      intronic chr8:42201730(+) A-I      intronic chr8:42220487(+) A-I      intronic chr8:42201662(+) A-I      intronic chr8:42201754(+) A-I      intronic chr8:42222506(+) A-I      intronic chr8:42223633(+) A-I      intronic chr8:42220442(+) A-I      intronic chr8:42201401(+) A-I      intronic chr8:42220624(+) A-I      intronic chr8:42221842(+) A-I      intronic chr8:42201664(+) A-I      intronic chr8:42223550(+) A-I      intronic chr8:42221944(+) A-I      intronic chr8:42220835(+) A-I      intronic chr8:42215763(+) A-I      intronic chr8:42215848(+) A-I      intronic chr8:42197311(+) A-I      intronic chr8:42220791(+) A-I      intronic chr8:42210406(+) A-I      intronic chr8:42219620(+) A-I      intronic chr8:42210909(+) A-I      intronic chr8:42210753(+) A-I      intronic chr8:42221990(+) A-I      intronic chr8:42201661(+) A-I      intronic chr8:42221956(+) A-I      intronic chr8:42221947(+) A-I      intronic chr8:42197158(+) A-I      intronic chr8:42215269(+) A-I      intronic chr8:42221857(+) A-I      intronic chr8:42221706(+) A-I      intronic chr8:42215428(+) A-I      intronic chr8:42201677(+) A-I      intronic chr8:42222012(+) A-I      intronic chr8:42215277(+) A-I      intronic chr8:42221930(+) A-I      intronic chr8:42218375(+) A-I      intronic chr8:42221645(+) A-I      intronic chr8:42220441(+) A-I      intronic chr8:42197165(+) A-I      intronic chr8:42197317(+) A-I      intronic chr8:42220830(+) A-I      intronic chr8:42221873(+) A-I      intronic chr8:42215940(+) A-I      intronic chr8:42217605(+) A-I      intronic chr8:42222525(+) A-I      intronic chr8:42210471(+) A-I      intronic chr8:42210840(+) A-I      intronic chr8:42215344(+) A-I      intronic chr8:42215843(+) A-I      intronic chr8:42220844(+) A-I      intronic chr8:42219526(+) A-I      intronic chr8:42221836(+) A-I      intronic chr8:42221625(+) A-I      intronic chr8:42215905(+) A-I      intronic chr8:42215883(+) A-I      intronic chr8:42221921(+) A-I      intronic chr8:42208661(+) A-I      intronic chr8:42219577(+) A-I      intronic chr8:42210811(+) A-I      intronic chr8:42217833(+) A-I      intronic chr8:42200507(+) A-I      intronic chr8:42221545(+) A-I      intronic chr8:42197289(+) A-I      intronic chr8:42221860(+) A-I      intronic chr8:42221912(+) A-I      intronic chr8:42220467(+) A-I      intronic chr8:42223497(+) A-I      intronic chr8:42221969(+) A-I      intronic chr8:42220978(+) A-I      intronic chr8:42220797(+) A-I      intronic chr8:42220490(+) A-I      intronic chr8:42220896(+) A-I      intronic chr8:42217828(+) A-I      intronic chr8:42220961(+) A-I      intronic chr8:42215842(+) A-I      intronic chr8:42220843(+) A-I      intronic chr8:42200257(+) A-I      intronic chr8:42210752(+) A-I      intronic chr8:42219532(+) A-I      intronic chr8:42221778(+) A-I      intronic chr8:42217737(+) A-I      intronic chr8:42197336(+) A-I      intronic chr8:42220889(+) A-I      intronic chr8:42197164(+) A-I      intronic chr8:42208437(+) A-I      intronic chr8:42228661(+) A-I      intronic chr8:42215976(+) A-I      intronic chr8:42222612(+) A-I      intronic chr8:42200318(+) A-I      intronic chr8:42215857(+) A-I      intronic chr8:42200331(+) A-I      intronic chr8:42221503(+) A-I      intronic chr8:42221913(+) A-I      intronic chr8:42200258(+) A-I      intronic chr8:42212839(+) A-I      intronic chr8:42217607(+) A-I      intronic chr8:42201601(+) A-I      intronic chr8:42221710(+) A-I      intronic chr8:42220967(+) A-I      intronic chr8:42222482(+) A-I      intronic chr8:42217827(+) A-I      intronic chr8:42222009(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	POLB	chr8:42201661(+) A-I intron -    22028664 chr8:42201662(+) A-I intron -    22028664 chr8:42201664(+) A-I intron -    22028664 chr8:42201668(+) A-I intron -    22028664 chr8:42201670(+) A-I intron -    22028664 chr8:42201677(+) A-I intron -    22028664 chr8:42201730(+) A-I intron -    22028664 chr8:42201754(+) A-I intron -    22028664 chr8:42196583(+) T-C exon CDS    21725310 chr8:42210343(+) A-G intron -    22484847 chr8:42210471(+) A-G intron -    22484847 chr8:42210752(+) A-G intron -    22484847 chr8:42210753(+) A-G intron -    22484847 chr8:42210766(+) A-G intron -    22484847 chr8:42210768(+) A-G intron -    22484847 chr8:42210811(+) A-G intron -    22484847 chr8:42215269(+) A-G intron -    22484847 chr8:42215277(+) A-G intron -    22484847 chr8:42215344(+) A-G intron -    22484847 chr8:42215345(+) A-G intron -    22484847 chr8:42215428(+) A-G intron -    22484847 chr8:42215465(+) A-G intron -    22484847 chr8:42215763(+) A-G intron -    22484847 chr8:42215843(+) A-G intron -    22484847 chr8:42215848(+) A-G intron -    22484847 chr8:42215857(+) A-G intron -    22484847 chr8:42215883(+) A-G intron -    22484847 chr8:42215899(+) A-G intron -    22484847 chr8:42215905(+) A-G intron -    22484847 chr8:42220487(+) A-G intron -    22484847 chr8:42220883(+) A-G intron -    22484847 chr8:42220889(+) A-G intron -    22484847 chr8:42221544(+) A-G intron -    22484847 chr8:42221548(+) A-G intron -    22484847 chr8:42221606(+) A-G intron -    22484847 chr8:42221619(+) A-G intron -    22484847 chr8:42221625(+) A-G intron -    22484847 chr8:42221628(+) A-G intron -    22484847 chr8:42221645(+) A-G intron -    22484847 chr8:42221697(+) A-G intron -    22484847 chr8:42221831(+) A-G intron -    22484847 chr8:42221896(+) A-G intron -    22484847 chr8:42221913(+) A-G intron -    22484847 chr8:42221921(+) A-G intron -    22484847 chr8:42221930(+) A-G intron -    22484847 chr8:42221947(+) A-G intron -    22484847 chr8:42221982(+) A-G intron -    22484847 chr8:42221990(+) A-G intron -    22484847 chr8:42222612(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	POLB	chr8:42196112-42196113(+) m6A 5'UTR//exon       24981863 chr8:42196169-42196170(+) m6A 5'UTR//CDS//exon//intron       24981863 chr8:42229093-42229094(+) m6A 3'UTR//CDS//exon       - chr8:42229119-42229120(+) m6A 3'UTR//CDS//exon       - chr8:42229153-42229154(+) m6A 3'UTR//CDS//exon       - chr8:42229161-42229162(+) m6A 3'UTR//CDS//exon       - chr8:42229196-42229197(+) m6A 3'UTR//CDS//exon       -

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hiv1-miR-H1	Exosome Jurkat-derived T cell line (J77cl20)     21505438
	POLB	Chromatin K562 cells     - Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Cytosol K562 cells     - Exosome Blood     - Membrane HCC cell line (HepG2)     - Nucleolus K562 cells     - Nucleus HCC cell line (HepG2)|K562 cells     - Ribosome HEK-293 cells     22199352 Ribosome-free cytosol Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: hiv1-miR-H1
Interactor2: POLB

Evidence Support:

Prediction-Evidence	miRanda//Rep//RNAHybrid//Targetscan
Support Database	RepTar//VmiReg