Basic Information:

  VIRBase ID:  

VHID00688984

  Virus:  

Human immunodeficiency virus 1 (HIV-1)

  Host:  

Homo sapiens

  Confidence Score:  

0.2202

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hiv1-miR-H1:  MIMAT0004480          ITGA2:  NR_073104     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hiv1-miR-H1	ITGA2
miRBase Accession/Entrez ID	MIMAT0004480	3673
Organism	Human immunodeficiency virus 1 (HIV-1)	Homo sapiens
Category	miRNA	mRNA
Alias	-	BR//CD49B//GPIa//HPA-5//VLA-2//VLAA2

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	ITGA2	chr5:52329031(+) A-I      intronic chr5:52328952(+) A-I      intronic chr5:52315565(+) A-I      intronic chr5:52315430(+) A-I      intronic chr5:52315442(+) A-I      intronic chr5:52329527(+) A-I      intronic chr5:52329555(+) A-I      intronic chr5:52329528(+) A-I      intronic chr5:52314750(+) A-I      intronic chr5:52388690(+) A-I      3'UTR chr5:52388691(+) A-I      3'UTR chr5:52388684(+) A-I      3'UTR chr5:52388662(+) A-I      3'UTR chr5:52388678(+) A-I      3'UTR chr5:52388676(+) A-I      3'UTR chr5:52299658(+) A-I      intronic chr5:52301291(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	ITGA2	chr5:52389815(+) A-I intron -    21960545 chr5:52389307(+) A-I intron -    21960545

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	ITGA2	chr5:52285196-52285197(+) m6A 5'UTR       - chr5:52285252-52285253(+) m6A 5'UTR       - chr5:52285262-52285263(+) m6A 5'UTR       - chr5:52285291-52285292(+) m6A 5'UTR       - chr5:52387173-52387174(+) m6A 3'UTR       26404942

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hiv1-miR-H1	Exosome Jurkat-derived T cell line (J77cl20)     21505438
	ITGA2	Cytosol HCC cell line (HepG2)     - Exosome Blood     - Insoluble cytoplasm HCC cell line (HepG2)     - Nucleoplasm K562 cells     - Nucleus HCC cell line (HepG2)     -

Interaction Network (The top 100 interactions):

Interactor1: hiv1-miR-H1
Interactor2: ITGA2

Evidence Support:

Prediction-Evidence	PITA//Targetscan
Support Database	VmiReg