Detail Information

Basic Information:


  VIRBase ID:  

VHID00687862

  Virus:  

Human immunodeficiency virus 1 (HIV-1)

  Host:  

Homo sapiens

  Confidence Score:  

0.2202

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hiv1-miR-H1:           SPATA8:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hiv1-miR-H1 SPATA8
miRBase
Accession/Entrez ID		 MIMAT0004480 145946
Organism Human immunodeficiency virus 1 (HIV-1) Homo sapiens
Category miRNA lncRNA
Alias - SRG8

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hiv1-miR-H1
Exosome Jurkat-derived T cell line (J77cl20)     21505438
SPATA8
Exosome Blood     -

Related Drug Information:


Resource Symbol Drug Name PubChem ID
RNAactDrug SPATA8
6-Amino-N-[3-[4-(4-morpholinyl)pyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl]phenyl]-3-pyridinecarboxamide       9956222
Benzamide, N-[4-[2-ethyl-4-(3-methylphenyl)-5-thiazolyl]-2-pyridinyl]-       9952773
1,2-Ethanediamine, N-(1,8-dimethylimidazo(1,2-a)quinoxalin-4-yl)-, monohydrochloride       9926054
Tivozanib       9911830
Zibotentan       9910224
5-(4-Fluorophenyl)-2-ureidothiophene-3-carboxamide       9903786
PI-103       9884685
7-Epi-10-deacetylbaccatin III       9872117
Osi-930       9868037
2-(4-(Benzo[d][1,3]dioxol-5-yl)-2-tert-butyl-1H-imidazol-5-yl)-6-methylpyridine       9858940
Desmethyleleutherobin       9830867
N-[(2R)-2,3-Dihydroxypropoxy]-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzamide       9826528
9H-Purine, 6-(ethylthio)-9-beta-D-ribofuranosyl-(8CI)(9CI)       95846
6-Benzylthioinosine       95263
6-Hydrazinopurine       94902
Tiotixene       941651
Pentamidine isethionate       8813
Benzethonium chloride       8478
(E)-1-(2-Hydroxyphenyl)-3-((1R,4R)-5-(pyridin-2-yl)-2,5-diazabicyclo[2.2.1]heptan-2-yl)prop-2-en-1-one       78243717
3-Amino-7-(dimethylamino)-5-phenylphenazinium chloride       75442
5-Methyl-1,10-phenanthroline       72791
N-(3-Methylphenyl)-4-pyridin-4-yl-1,3-thiazol-2-amine       704473
(S)-N-Hydroxy-4-(3-methyl-2-phenylbutanamido)benzamide       6918848
Belinostat       6918638
2-(2-Chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide       6918454
Daporinad       6914657
N-(5-(4-Chloro-3-(N-(2-hydroxyethyl)sulfamoyl)phenyl)-4-methylthiazol-2-yl)acetamide       6852167
1-(2-Pyridylazo)-2-naphthol       6825
Triciribine       65399
2-Amino-6-methoxypurine       65275
AICA ribonucleotide       65110
Tanespimycin       6505803
Ispinesib mesylate       6450816
Axitinib       6450551
Pelitinib       6445562
Dacinostat       6445533
Phylanthoside       6436218
4-(N-Hydroxyacetamido)stilbene       6433723
Cytarabine       6253
Colchicine       6167
Gemcitabine       60750
Topotecan       60700
8-Hydroxy verrucarin A       5794769
Mitomycin       5746
3-(2-Phenyl-5-pyridin-4-yl-1H-imidazol-4-yl)phenol;hydrochloride       57399804
5-[2-[4-(Aminomethyl)phenyl]-5-pyridin-4-yl-1H-imidazol-4-yl]-2-chlorophenol;hydrochloride       57399803
(2-(Phenylamino)-1,4-phenylene)bis((4-(pyrrolidin-1-yl)piperidin-1-yl)methanone)       57339144
1-(3-((((2R,3S,4R,5R)-5-(4-Amino-5-bromo-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)(isopropyl)amino)propyl)-3-(4-(tert-butyl)phenyl)urea       56962337
N-[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[(1-oxo-1,4-thiazinan-4-yl)methyl]furan-2-yl]quinazolin-4-amine;2,2,2-trifluoroacetic acid       56603975
Sodium dimethyldithiocarbamate       560256
Halichondrin B       5488895
Ethyl red       54832
Phyllanthastatin 1       5477587
Austocystin D       5470400
Viridenomycin       54686463
Antineoplastic-647246       5467055
Antineoplastic-643001       5466797
Antineoplastic-641454       5466704
Mito-tempol       54613387
3-Methoxy-5H-8-methoxy-isoindolo[2,1-A]quinoxalin-6-one       54612826
Olivomycin Transformation       54610760
(10R,13R,16R,19S)-16-Butan-2-yl-3-(3-chloro-2-hydroxypropyl)-10,11,14-trimethyl-13-propan-2-yl-4-oxa-1,8,11,14,17-pentazabicyclo[17.3.0]docosane-2,5,9,12,15,18-hexone       5459202
Eupalmerin acetate       5459169
18-Acetoxyaphidicolin       5458777
2-Methylolivacinium acetate       5458752
Thiram       5455
Temozolomide       5394
(Z)-3,3',4,4',5-Pentamethoxystilbene       5386627
2-Methoxy-5-[(E)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenol       5386397
(1E,4E)-1,5-Dipyridin-3-ylpenta-1,4-dien-3-one       5382674
Rubremetinium chloride       5351504
Combretastatin A4       5351344
1-Piperidineethanol, alpha-[p-(p-chlorostyryl)phenyl]-       5351150
N-[4-[(4-Ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)benzamide       53340664
Palbociclib       5330286
Bosutinib       5328940
Vorinostat       5311
Bis(2-hydroxy-1-naphthyl) disulfide       521106
6-Chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide       5113032
Tubastatin A       49850262
Alectinib       49806720
Shikonin       479503
Pentamidine       4735
2-[(4s)-6-(4-Chlorophenyl)-8-Methoxy-1-Methyl-4h-[1,2,4]triazolo[4,3-A][1,4]benzodiazepin-4-Yl]-N-Ethylacetamide       46943432
(S)-(+)-Tert-Butyl 2-(4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetate       46907787
3-(4-(4-(2-(3-((Dimethylamino)methyl)phenyl)-1H-pyrrolo[2,3-b]pyridin-4-yl)-1-ethyl-1H-pyrazol-3-yl)phenyl)-1,1-dimethylurea       46885626
2-Cyclohexyl-N-(1-isopropylpiperidin-4-yl)-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazolin-4-amine       46224516
N-(6,6-Dimethyl-5-(1-methylpiperidine-4-carbonyl)-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazol-3-yl)-3-methylbutanamide       46191454
Ethoxycurcumin trithiadiazolaminomethylcarbonte       45028266
N-(2,2,2-Trifluoroethyl)-N-{4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl}benzenesulfonamide       447912
Okadaic acid       446512
1-(6,7-Dimethoxyquinazolin-4-yl)-3-(pyridin-2-yl)-1H-1,2,4-triazol-5-amine       44551660
Tretinoin       444795
Dabrafenib       44462760
Refametinib       44182295
Glaucarubinone       441796
[(1S,4R,5R,6R,7S,8R,11R,13S,17S,18S,19R)-4,5,17-Trihydroxy-6,14,18-trimethyl-9,16-dioxo-3,10-dioxapentacyclo[9.8.0.01,7.04,19.013,18]nonadec-14-en-8-yl] 2-methylbutanoate       441784
6alpha-Senecioyloxychaparrinone       431194
Foretinib       42642645
Benzofurazan, 4-(4-methyl-1-piperazinyl)-7-nitro-, 3-oxide       42640
(2S)-2-[[2-(2,3-Dihydro-1H-inden-5-yloxy)-9-[(4-phenylphenyl)methyl]-6-purinyl]amino]-3-phenyl-1-propanol       42623900
3-Chloro-4-(4-chlorophenyl)-5H-furan-2-one       405305
3-(3-Hydroxy-4-methoxybenzyl)-5,7-dihydroxychroman-4-one       404571
Cbz-[Lys3]-Didemnin B       398464
1,6-Bis[4-(4-aminophenoxy)phenyl]diamantane       397904
4-(5-Fluoro-1,3-benzothiazol-2-yl)-2-methylaniline       396813
7-Epi-3,4-bis-nor-dolastatin 11       396354
Amino MMI-S02 CI       393532
2,6-Dibromo-4-[(6,7-dimethoxyquinazolin-4-yl)amino]phenol       3796
3-Demethyl-3-butyrylthiocolchicine       379108
(7-Acetamido-1,2-dimethoxy-10-methylsulfanyl-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-3-yl) ethyl carbonate       379107
6-Methyl-2-phenyl-1H-1,8-naphthyridin-4-one       377425
Colchicine analog       369942
Etoposide       36462
Paclitaxel       36314
1,2,4,5-Tetrazine, 3,6-bis(1-azetidinyl)-       362170
3,4-Dihydroxynaphthalene-2-carboxylic acid       356138
2,3-Dimethylbenzo[g]quinoxaline-5,10-dione       353644
5-Fluorouracil       3385
Colchicine, 17-chloro-       33463
Doxorubicin       31703
Cetalkonium chloride       31202
4,4'-(Piperazine-1,4-diyl)dibenzaldehyde       3006251
Dibenzoylfuran deriv       282697
AT 116, benzylamine salt       282523
2-Amino-3-[1,3-benzodioxol-5-yl(diphenyl)methyl]sulfanylpropanoic acid       281457
Tamoxifen       2733526
Basic red 2       2723800
[5-[2,4-Bis((3S)-3-methylmorpholin-4-yl)pyrido[2,3-d]pyrimidin-7-yl]-2-methoxyphenyl]methanol       25262965
2-(4-Methyl-1,4-diazepan-1-yl)-N-((5-methylpyrazin-2-yl)methyl)-5-oxo-5H-benzo[4,5]thiazolo[3,2-a][1,8]naphthyridine-6-carboxamide       25257557
Omipalisib       25167777
Ruxolitinib       25126798
Cabozantinib       25102847
Navitoclax       24978538
Tert-Butyl (4-(3-((7-(hydroxyamino)-7-oxoheptyl)carbamoyl)isoxazol-5-yl)phenyl)carbamate       24951314
Quizartinib       24889392
Ponatinib       24826799
Vismodegib       24776445
4-(6,6-Dimethyl-4-oxo-3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazol-1-yl)-2-((1r,4r)-4-hydroxycyclohexylamino)benzamide       24772860
Cudc-101       24756910
5-(Naphthalen-2-yl)-1-(3,4,5-trimethoxyphenyl)-1H-imidazole       24205849
(2-Methoxy-9,10-dihydrophenanthren-3-yl)methyl-dimethyl-(phenylsulfanylmethyl)azanium;bromide       24200489
Vincaleukoblastine       241903
N-(3-(5-Chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide       24180719
Bicalutamide       2375
Olaparib       23725625
Lobendazole       22752
Aristolochic acid       2236
Nutlin-3       216345
Lenalidomide       216326
8-Amino-5-methyl-6-phenylphenanthridin-5-ium bromide       21144180
Kinetin riboside       20345
Cladribine       20279
1,3,5-Triazin-2(1H)-one, 4-amino-1-beta-D-ribofuranosyl-       1805
8-Chloro-cyclicamp       17856967
Erlotinib       176870
Thiocolchicine       17648
Enzastaurin       176167
4-Methyl-3-(1-methyl-6-(pyridin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-ylamino)-N-(3-(trifluoromethyl)phenyl)benzamide       16747388
Gsk-690693       16725726
Fedratinib       16722836
N-(3-{[2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-1H-imidazo[4,5-c]pyridin-6-yl]oxy}phenyl)-4-[2-(morpholin-4-yl)ethoxy]benzamide       16095342
5-Chloro-N4-(2-(isopropylsulfonyl)phenyl)-N2-(2-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)phenyl)pyrimidine-2,4-diamine       16038120
Butyltriphenylphosphonium bromide       159628
Docetaxel       148124
Homidium bromide       14710
7-Epi-10-deacetyltaxol       14355298
4-N,N-Bis(2-chloroethyl)amino-2-tolualdehyde       141295
1-(Tert-Butyl)-3-(2-((4-(diethylamino)butyl)amino)-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl)urea       1401
N-[5-[5-[4-[2-(Dimethylamino)ethoxy]phenyl]-2-pyridin-4-ylfuran-3-yl]-2,3-dihydroinden-1-ylidene]hydroxylamine;hydrochloride       136207967
Astrazon Orange R       135747272
(Z)-3-((3-((Dimethylamino)methyl)phenylamino)(phenyl)methylene)-N,N-dimethyl-2-oxoindoline-6-carboxamide       135659062
Talazoparib       135565082
N,N-Dimethyl-2-[4-[4-(1-nitroso-2,3-dihydroinden-5-ylidene)-5-(1H-pyridin-4-ylidene)-1H-imidazol-2-yl]phenoxy]ethanamine       135564599
(2Z,5Z)-3-Methoxy-2-[(5-methyl-4-pentyl-1H-pyrrol-2-yl)methylidene]-5-pyrrol-2-ylidenepyrrole       135455579
Pac-1       135421197
Osi-027       135398516
Akt inhibitor VIII       135398501
Yuccaol A       131752044
Methotrexate       126941
Lestaurtinib       126565
10-Desacetylbaccatin III       125001
Berberine chloride       12456
Dactolisib       11977753
Veliparib       11960529
(Z)-But-2-enedioic acid;3-[4-[(3Z)-3-(2-chlorothioxanthen-9-ylidene)propyl]piperazin-1-yl]-N-methylpropanamide       11954261
BAY 61-3606 dihydrochloride       11784504
N-[3-[[5-Bromo-4-[[2-(1H-imidazol-5-YL)ethyl]amino]-2-pyrimidinyl]amino]phenyl]-1-pyrrolidinecarboxamide       11754511
Trametinib       11707110
4,4'-(6-(2-(Difluoromethyl)-1H-benzo[d]imidazol-1-yl)-1,3,5-triazine-2,4-diyl)dimorpholine       11647372
Crizotinib       11626560
Idelalisib       11625818
5-(3-Methoxy-4-((4-methoxybenzyl)oxy)benzyl)pyrimidine-2,4-diamine       11617559
Benzamide, 4-((1R)-1-aminoethyl)-N-1H-pyrrolo(2,3-b)pyridin-4-yl-, hydrochloride (1:1)       11507964
(S)-N-((S)-1-Cyclohexyl-2-oxo-2-((3aR,7aS)-6-phenethyloctahydro-1H-pyrrolo[2,3-c]pyridin-1-yl)ethyl)-2-(methylamino)propanamide       11503417
5-(2-Phenylpyrazolo[1,5-A]pyridin-3-YL)-1H-pyrazolo[3,4-C]pyridazin-3-amine       11493598
Linifanib       11485656
Bafetinib       11387605
N-(6-Fluoro-1H-indazol-5-yl)-6-methyl-2-oxo-4-[4-(trifluoromethyl)phenyl]-3,4-dihydro-1H-pyridine-5-carboxamide       11373846
4-(2,6-Dichlorobenzamido)-N-(piperidin-4-yl)-1H-pyrazole-3-carboxamide       11338033
8-(4-Dibenzothienyl)-2-(4-morpholinyl)-4H-1-benzopyran-4-one       11327430
Pararosaniline hydrochloride       11292
Amuvatinib       11282283
(S)-5-(3-Fluorophenyl)-N-(piperidin-3-yl)-3-ureidothiophene-2-carboxamide       11152667
Setoglaucine       107404
[(4-Methylphenyl)methyl](triphenyl)arsanium bromide       10672721
Dequalinium chloride       10649
7-Ethyl-10-hydroxycamptothecin       104842
VX-702       10341154
Afatinib       10184653
Selumetinib       10127622
N-(3-{[5-Iodo-4-({3-[(Thiophen-2-Ylcarbonyl)amino]propyl}amino)pyrimidin-2-Yl]amino}phenyl)pyrrolidine-1-Carboxamide       10077147
Masitinib       10074640
Tocladesine       100299
PDK1 inhibitor AR-12       10027278
25-Dihydrosaframycin A       100180
1,2-Didemethylcolchicine       100174
14,15-cyclopropano-1-n-formyl-vinorelbine-sulfate       -
14,15-cyclopropano-8'-desmethylene-vinblastine-sulfate       -
1,4-dimethoxy-7-azaisoindole[2,1-a]quinoxalin-6(5h)-one       -
1-piperidinecarbodithioic acid, antimony complex       -
;2-(3-((2-methoxybenzyl)amino)propyl)-7-(3-((4-((3-(meth...       -
;3,5-bis(4-hydroxy-3-methoxystyryl)-N-(4-fluorophenyl)-1...       -
5,6-ethylenediquino[3,2-b       -
5-iodo-2-(2-phenoxyacetamido)benzamide       -
5-methoxy-2-(2-phenoxyacetamido)benzamide       -
;9-benzyl-7-benzyloxy-2-benzyl-1-methyl-9H-carbolinium b...       -
ammonium, trimethyl(1-phenyldodecyl)-, p-toluenesulfonate       -
antibiotic 2-79-a(5)       -
Basic Fuchsin       -
benzo[1,2-b:5,4-b']dithiophene-4,8-dione, 3-methyl-       -
benzo[b]naphtho[2,3-d]furan-6,11-dione, 4-chloro-3-hydroxy       -
Cisplatin       -
Colchicine Derivative       -
;(E)-5-chloro-3-((6-(4-chlorophenyl)-2-cyclopropylimidaz...       -
gamitrinib-g4       -
Genentech Cpd 10       -
gramicidin       -
g-tpp       -
JW-7-24-1       -
KIN001-236       -
KIN001-244       -
KIN001-260       -
KIN001-266       -
KIN001-270       -
leucinostatine d       -
methylbenzethonium chloride (usan)       -
MPS-1-IN-1       -
naphth[2,3-d]oxazol-9-one, 2-methyl-4-(phenylimino)-       -
naphtho[2,1-b]quinolizinium, 5-chloro-7-methyl- perchlorate       -
naphtho[2,3-b]furan-4,9-dione, 2-bromo-       -
N-methyl-N-(4-(3-(pyrrolidin-1-yl)propoxy)benzyl)-4-(2,6...       -
NPK76-II-72-1       -
Nutlin-3a (-)       -
pararosaniline pamoate       -
peptide isolated from viscum alblum extract (iscador)       -
phosphonium, triphenylpropenyl-, bromide, (e)- (8ci)       -
QL-X-138       -
QL-XI-92       -
QL-XII-47       -
rhodium dimer       -
riboprine(usan)       -
rTRAIL       -
SB52334       -
Taxol derivative       -
THZ-2-102-1       -
THZ-2-49       -
TL-1-85       -
TL-2-105       -
tp38-279       -
Tyrothricin       -
VNLG/124       -
WZ3105       -
XMD13-2       -
XMD14-99       -
XMD15-27       -
z-1-(4-methylthio-2-(3,4,5-trimethoxyphenyl)ethene       -
;(Z)-4-fluoro-N-(2-hydroxy-3-methoxy-6-(3,4,5-trimethoxy...       -
;(Z)-5-Chloro-2-(1-methyl-5-nitroimidazole-2-ylmethylene...       -

Interaction Network (The top 100 interactions):


Interactor1: hiv1-miR-H1
Interactor2: SPATA8

Evidence Support:


Prediction-Evidence miRanda//RNAHybrid
Support Database VmiReg

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