Basic Information:

  VIRBase ID:  

VHID00684437

  Virus:  

Human immunodeficiency virus 1 (HIV-1)

  Host:  

Homo sapiens

  Confidence Score:  

0.2202

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hiv1-miR-N367:  MIMAT0004478          HTRA1:  NM_002775     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hiv1-miR-N367	HTRA1
miRBase Accession/Entrez ID	MIMAT0004478	5654
Organism	Human immunodeficiency virus 1 (HIV-1)	Homo sapiens
Category	miRNA	mRNA
Alias	-	ARMD7//CADASIL2//CARASIL//HtrA//L56//ORF480//PRSS11

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	HTRA1	chr10:124273079(+) A-I      intronic chr10:124242248(+) A-I      intronic chr10:124242227(+) A-I      intronic chr10:124242211(+) A-I      intronic chr10:124242263(+) A-I      intronic chr10:124273080(+) A-I      intronic chr10:124225890(+) A-I      intronic chr10:124273373(+) A-I      intronic chr10:124242258(+) A-I      intronic chr10:124242283(+) A-I      intronic chr10:124242180(+) A-I      intronic chr10:124242247(+) A-I      intronic chr10:124270624(+) A-I      intronic

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	HTRA1	chr10:124249003-124249004(+) m6A CDS       22575960 chr10:124249113-124249114(+) m6A CDS       24284625 chr10:124266297-124266298(+) m6A CDS       24284625 chr10:124266366-124266367(+) m6A CDS       24284625 chr10:124266372-124266373(+) m6A CDS       24284625 chr10:124266383-124266384(+) m6A CDS       22575960 chr10:124266892-124266893(+) m6A CDS       22575960 chr10:124266913-124266914(+) m6A CDS       22575960 chr10:124271505-124271506(+) m6A CDS       24284625//24981863 chr10:124271517-124271518(+) m6A CDS       24284625//24981863 chr10:124273748-124273749(+) m6A CDS       24284625//24981863//22575960//22608085 chr10:124273807-124273808(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr10:124273892-124273893(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085 chr10:124273912-124273913(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085 chr10:124273937-124273938(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085 chr10:124273958-124273959(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085 chr10:124273967-124273968(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085 chr10:124274000-124274001(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085 chr10:124274043-124274044(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085 chr10:124274143-124274144(+) m6A 3'UTR       24284625//24981863//22608085 chr10:124274248-124274249(+) m6A 3'UTR       24284625//25456834//24981863//22575960//22608085 chr10:124274303-124274304(+) m6A 3'UTR       24284625//25456834//24981863//22575960//22608085

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	HTRA1	Cytoplasm Nasopharyngeal carcinoma cells     20498841 Exosome Blood     - Nucleus Nasopharyngeal carcinoma cells     20498841 Ribosome HEK-293 cells     22199352

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	hiv1-miR-N367	Topotecan       60700

Interaction Network (The top 100 interactions):

Interactor1: hiv1-miR-N367
Interactor2: HTRA1

Evidence Support:

Prediction-Evidence	miRanda//PITA
Support Database	VmiReg