Basic Information:

  VIRBase ID:  

VHID00683807

  Virus:  

Human immunodeficiency virus 1 (HIV-1)

  Host:  

Homo sapiens

  Confidence Score:  

0.2483

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hiv1-miR-N367:  MIMAT0004478          CCR5:  NM_000579     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hiv1-miR-N367	CCR5
miRBase Accession/Entrez ID	MIMAT0004478	1234
Organism	Human immunodeficiency virus 1 (HIV-1)	Homo sapiens
Category	miRNA	mRNA
Alias	-	CC-CKR-5//CCCKR5//CCR-5//CD195//CKR-5//CKR5//CMKBR5//IDDM22

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	CCR5	chr3:46417215(+) A-I      3'UTR chr3:46417221(+) A-I      3'UTR chr3:46417219(+) A-I      3'UTR chr3:46417218(+) A-I      3'UTR chr3:46417270(+) A-I      3'UTR

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	CCR5	chr3:46417171(+) A-I exon 3'UTR    15258596 chr3:46417220(+) A-I exon 3'UTR    15258596 chr3:46417272(+) A-I exon 3'UTR    15258596 chr3:46417283(+) A-I exon 3'UTR    15258596

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	CCR5	chr3:46414562-46414563(+) m6A CDS       - chr3:46414676-46414677(+) m6A CDS       - chr3:46415165-46415166(+) m6A CDS       - chr3:46415219-46415220(+) m6A CDS       - chr3:46415242-46415243(+) m6A CDS       - chr3:46415309-46415310(+) m6A CDS       - chr3:46415457-46415458(+) m6A 3'UTR       - chr3:46416453-46416454(+) m6A 3'UTR       27773535

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	CCR5	Exosome Blood     -

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	hiv1-miR-N367	Topotecan       60700

Interaction Network (The top 100 interactions):

Interactor1: hiv1-miR-N367
Interactor2: CCR5

Evidence Support:

Prediction-Evidence	cRep//miRanda//PITA//Rep//Targetscan
Support Database	RepTar//VmiReg