Basic Information:

  VIRBase ID:  

VHID00669917

  Virus:  

JC polyomavirus (JCPyV)

  Host:  

Homo sapiens

  Confidence Score:  

0.2381

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      jcv-miR-J1-5p:  MIMAT0009147          TBRG1:  NR_016021     

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Interactor Information:

	Interactor1	Interactor2
Symbol	jcv-miR-J1-5p	TBRG1
miRBase Accession/Entrez ID	MIMAT0009147	84897
Organism	JC polyomavirus (JCPyV)	Homo sapiens
Category	miRNA	mRNA
Alias	-	NIAM//TB-5

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	TBRG1	chr11:124504434(+) A-I      3'UTR chr11:124504459(+) A-I      3'UTR chr11:124504463(+) A-I      3'UTR chr11:124504109(+) A-I      3'UTR chr11:124504433(+) A-I      3'UTR chr11:124504115(+) A-I      3'UTR chr11:124503611(+) A-I      3'UTR chr11:124503607(+) A-I      3'UTR chr11:124504472(+) A-I      3'UTR chr11:124504471(+) A-I      3'UTR chr11:124504469(+) A-I      3'UTR chr11:124504468(+) A-I      3'UTR chr11:124503587(+) A-I      3'UTR chr11:124503561(+) A-I      3'UTR chr11:124504083(+) A-I      3'UTR chr11:124504492(+) A-I      3'UTR chr11:124504476(+) A-I      3'UTR chr11:124504073(+) A-I      3'UTR chr11:124504079(+) A-I      3'UTR chr11:124504070(+) A-I      3'UTR chr11:124504436(+) A-I      3'UTR chr11:124504444(+) A-I      3'UTR chr11:124504119(+) A-I      3'UTR chr11:124504440(+) A-I      3'UTR chr11:124503570(+) A-I      3'UTR chr11:124503568(+) A-I      3'UTR chr11:124504099(+) A-I      3'UTR chr11:124503562(+) A-I      3'UTR chr11:124497459(+) A-I      intronic

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	TBRG1	chr11:124492768-124492769(+) m6A 5'UTR//exon       24284625//25456834//24981863 chr11:124492893-124492894(+) m6A 5'UTR//exon       24284625//25456834//24981863 chr11:124492976-124492977(+) m6A 5'UTR//exon       24981863 chr11:124501965-124501966(+) m6A exon//intron       24284625 chr11:124501997-124501998(+) m6A 3'UTR//CDS//exon       24284625 chr11:124502061-124502062(+) m6A 3'UTR//CDS//exon       24284625//24981863//22608085 chr11:124502134-124502135(+) m6A 3'UTR//exon       24284625//24981863//27773535//22608085 chr11:124502186-124502187(+) m6A 3'UTR//exon       24284625//24981863//27773535//22608085 chr11:124504151-124504152(+) m6A 3'UTR       24981863 chr11:124504182-124504183(+) m6A 3'UTR       24981863 chr11:124504220-124504221(+) m6A 3'UTR       24981863 chr11:124504234-124504235(+) m6A 3'UTR       24981863 chr11:124504240-124504241(+) m6A 3'UTR       24981863 chr11:124504246-124504247(+) m6A 3'UTR       24981863 chr11:124504258-124504259(+) m6A 3'UTR       24981863 chr11:124504279-124504280(+) m6A 3'UTR       24981863

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	jcv-miR-J1-5p	Nucleus PML tissue     32324824
	TBRG1	Cytoplasm Nasopharyngeal carcinoma cells     20498841 Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Nucleoplasm K562 cells     - Nucleus Nasopharyngeal carcinoma cells     20498841 Nucleus HCC cell line (HepG2)|HeLa-S3 cells     - Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: jcv-miR-J1-5p
Interactor2: TBRG1

Evidence Support:

Prediction-Evidence	cRep//miRanda//PITA
Support Database	RepTar//VmiReg