Detail Information

Basic Information:


  VIRBase ID:  

VHID00658183

  Virus:  

Suid alphaherpesvirus 1 (Pseudorabies virus JS-2012 strain)

  Host:  

Sus scrofa

  Confidence Score:  

0.5908

  Interaction Type:  

Virus-Host interaction

Interactor Information:


Interactor1 Interactor2
Symbol prv-miR-6-5p ITPKA
miRBase
Accession/Entrez ID		 prv-miR-6-5p 100516235
Organism Suid alphaherpesvirus 1 (Pseudorabies virus JS-2012 strain) Sus scrofa
Category miRNA mRNA
Alias - -

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase ITPKA
chr1:144939235-144939236(-) m6A 3'UTR       28267806
chr1:144939382-144939383(-) m6A 3'UTR       28267806
chr1:144939388-144939389(-) m6A 3'UTR       28267806
chr1:144939426-144939427(-) m6A 3'UTR       28267806
chr1:144939447-144939448(-) m6A 3'UTR       28267806
chr1:144939509-144939510(-) m6A CDS       28267806
chr1:144940858-144940859(-) m6A CDS       28267806
chr1:144941176-144941177(-) m6A CDS       28267806
chr1:144947066-144947067(-) m6A CDS       28267806

Interaction Network (The top 100 interactions):


Interactor1: prv-miR-6-5p
Interactor2: ITPKA

Evidence Support:


Weak-Evidence Small RNA sequencing
Prediction-Evidence miRanda//RNAHybrid
Support Database ViRBase

References:


PMID 26998839 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line PK15 cells Interactor2 expression None
Description A total of 36 miRNAs, including 11 known miRNAs and 25 novel miRNAs, were mapped to the PRV JS-2012 genome. We used RNAhybrid and miRanda software to scan the potential viral gene targets for these miRNAs. We scanned the 3'UTRs of PRV-encoded genes, including the LLT and found that each gene can be targeted by one or more miRNAs.

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