Detail

Detail Information

Basic Information:

VIRBase ID:

VHID00655374

Virus:

Suid alphaherpesvirus 1 (Pseudorabies virus JS-2012 strain)

Host:

Sus scrofa

Confidence Score:

0.5908

Interaction Type:

Virus-Host interaction

Interactor Information:

	Interactor1	Interactor2
Symbol	prv-miR-10-5p	IGF2R
miRBase Accession/Entrez ID	prv-miR-10-5p	397214
Organism	Suid alphaherpesvirus 1 (Pseudorabies virus JS-2012 strain)	Sus scrofa
Category	miRNA	mRNA
Alias	-	M6P/IGF2R

RNA Modification:

Resource

Symbol

ModificationPosition

Type

Genomic Context

PMID

RMBase

IGF2R

chr1:9168224-9168225(-)	m6A	3'UTR	28267806
chr1:9168262-9168263(-)	m6A	3'UTR	28267806
chr1:9168268-9168269(-)	m6A	3'UTR	28267806
chr1:9168324-9168325(-)	m6A	3'UTR	28267806
chr1:9168341-9168342(-)	m6A	CDS	28267806
chr1:9168563-9168564(-)	m6A	CDS	28267806
chr1:9183042-9183043(-)	m6A	CDS	28267806
chr1:9183090-9183091(-)	m6A	CDS	28267806
chr1:9190829-9190830(-)	m6A	CDS	28267806
chr1:9190850-9190851(-)	m6A	CDS	28267806
chr1:9190875-9190876(-)	m6A	CDS	28267806
chr1:9191236-9191237(-)	m6A	CDS	28267806
chr1:9191245-9191246(-)	m6A	CDS	28267806
chr1:9219366-9219367(-)	m6A	CDS	28267806
chr1:9220837-9220838(-)	m6A	CDS	28267806
chr1:9220842-9220843(-)	m6A	CDS	28267806
chr1:9223230-9223231(-)	m6A	CDS	28267806
chr1:9228589-9228590(-)	m6A	CDS	28267806
chr1:9228606-9228607(-)	m6A	CDS	28267806
chr1:9228672-9228673(-)	m6A	CDS	28267806
chr1:9229511-9229512(-)	m6A	CDS	28267806
chr1:9229524-9229525(-)	m6A	CDS	28267806

Interaction Network (The top 100 interactions):

Interactor1: prv-miR-10-5p

Interactor2: IGF2R

Evidence Support:

Weak-Evidence	Small RNA sequencing
Prediction-Evidence	miRanda//RNAHybrid
Support Database	ViRBase

References:

PMID	26998839	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	PK15 cells	Interactor2 expression	None
Description	A total of 36 miRNAs, including 11 known miRNAs and 25 novel miRNAs, were mapped to the PRV JS-2012 genome. We used RNAhybrid and miRanda software to scan the potential viral gene targets for these miRNAs. We scanned the 3'UTRs of PRV-encoded genes, including the LLT and found that each gene can be targeted by one or more miRNAs.

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