Basic Information:

  VIRBase ID:  

VHID00641763

  Virus:  

Murid gammaherpesvirus 4 (MuHV-4)

  Host:  

Mus musculus

  Confidence Score:  

0.9374

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      mghv-miR-M1-7-5p:  MIMAT0001570          Ifitm3:  NM_025378     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	mghv-miR-M1-7-5p	Ifitm3
miRBase Accession/Entrez ID	MIMAT0001570	66141
Organism	Murid gammaherpesvirus 4 (MuHV-4)	Mus musculus
Category	miRNA	mRNA
Alias	-	1110004C05Rik//Cd225//Cdw217//DSPA2b//Fg//Fgls//fr//IP//IP15//mil//mil-1

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	Ifitm3	chr7:141010518-141010519(-) m6A CDS       24981863//25456834//25569111//22575960 chr7:141010589-141010590(-) m6A CDS       24981863//25456834//25569111//22575960 chr7:141010600-141010601(-) m6A CDS       25683224//24981863//25456834//25569111//22575960 chr7:141010640-141010641(-) m6A CDS       25683224//24981863//25456834//25569111//22575960 chr7:141010696-141010697(-) m6A 5'UTR       25683224//25412662//24981863//25456834//25569111//22608085//22575960 chr7:141010715-141010716(-) m6A 5'UTR       25683224//25412662//24981863//25456834//25569111//22608085//22575960 chr7:141010721-141010722(-) m6A 5'UTR       25683224//25412662//24981863//25456834//25569111//22608085//22575960 chr7:141010732-141010733(-) m6A 5'UTR       25683224//25412662//24981863//25456834//25569111//22608085//22575960

Interaction Network (The top 100 interactions):

Interactor1: mghv-miR-M1-7-5p
Interactor2: Ifitm3

Evidence Support:

Strong-Evidence	qRT-PCR//Western blot
Weak-Evidence	qCLASH
Support Database	ViRBase

References:

[1]PMID	31363027	Target region	None
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	B cells	Interactor2 expression	None
Description	Table S4. Host mRNA targets of mghv-miR-M1-7-5p and mghv-miR-M1-7-3p identified by qCLASH in HE2.1 B cells.

[2]PMID	31393953	Target region	None
Source	ViRBase	Interactor1 expression	Upregulation
Tissue or cell line	None	Interactor2 expression	Downregulation
Description	QCLASH-identified targeting miRNAs were: miR-8-5p for Ctsl, miR-7-5p for Ewsr1, miR-7-5p for Ifitm3, and miR-12-3p for Foxj3.