Detail Information

Basic Information:


  VIRBase ID:  

VHID00641000

  Virus:  

Murid gammaherpesvirus 4 (MuHV-4)

  Host:  

Mus musculus

  Confidence Score:  

0.9751

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      mghv-miR-M1-7-5p:           Ewsr1:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol mghv-miR-M1-7-5p Ewsr1
miRBase
Accession/Entrez ID		 MIMAT0001570 14030
Organism Murid gammaherpesvirus 4 (MuHV-4) Mus musculus
Category miRNA mRNA
Alias - Ew//Ews//Ewsh

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR Ewsr1
chr11:4976830(-) A-I      intronic
chr11:4975876(-) A-I      intronic
chr11:4976816(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED Ewsr1
chr11:5075873(-) A-I intron -    22524474
chr11:5076813(-) A-I intron -    22524474
chr11:5076827(-) A-I intron -    22524474

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase Ewsr1
chr11:5070021-5070022(-) m6A 3'UTR//exon       25683224//25412662//24981863
chr11:5070060-5070061(-) m6A 3'UTR//exon       25683224//25412662//24981863
chr11:5070076-5070077(-) m6A CDS//exon       25683224//25412662//24981863
chr11:5070244-5070245(-) m6A CDS//exon       25683224//25412662//24981863//25456834
chr11:5070262-5070263(-) m1A CDS//exon       26863196
chr11:5070277-5070278(-) m6A CDS//exon       25683224//25412662//24981863//25456834//25569111
chr11:5070289-5070290(-) m6A CDS//exon       25683224//25412662//24981863//25456834//25569111
chr11:5070341-5070342(-) m6A CDS//exon       25683224//25412662//24981863//25456834//25569111//22608085
chr11:5070374-5070375(-) m6A CDS//exon       25683224//25412662//24981863//25456834//25569111//22608085
chr11:5070419-5070420(-) m6A CDS//exon       25683224//25412662//24981863//25456834//25569111//22608085
chr11:5070427-5070428(-) m6A CDS//exon       25683224//25412662//24981863//25456834//25569111//22608085
chr11:5071013-5071014(-) m6A CDS//exon       25412662
chr11:5071052-5071053(-) m6A CDS//exon       25412662//24981863
chr11:5071097-5071098(-) m6A CDS//exon       25412662//24981863//22608085
chr11:5071129-5071130(-) m6A CDS//exon       25412662//24981863//22608085
chr11:5071434-5071435(-) m6A exon//intron       25412662//24981863//22608085
chr11:5071581-5071582(-) m6A CDS//exon       25412662//24981863//22608085
chr11:5071619-5071620(-) m6A CDS//exon       25412662//24981863//22608085
chr11:5072923-5072924(-) m6A CDS//exon       24981863//22608085
chr11:5072928-5072929(-) m6A CDS//exon       24981863//22608085
chr11:5072936-5072937(-) m6A CDS//exon       24981863//22608085
chr11:5078500-5078501(-) m6A CDS//exon       24981863//22608085
chr11:5078566-5078567(-) m6A CDS//exon       24981863//22608085
chr11:5078935-5078936(-) m6A CDS//exon//intron       24981863//22608085
chr11:5078950-5078951(-) m6A CDS//exon//intron       24981863//22608085
chr11:5082173-5082174(-) m6A exon//intron       25683224//24981863
chr11:5082181-5082182(-) m6A exon//intron       25683224//24981863
chr11:5082228-5082229(-) Y intron       26075521
chr11:5082240-5082241(-) m6A exon//intron       25683224//25412662//24981863
chr11:5082257-5082258(-) m6A CDS//exon//intron       25683224//25412662//24981863
chr11:5082354-5082355(-) m6A CDS//exon       25683224//25412662//24981863//22608085
chr11:5082365-5082366(-) m6A CDS//exon       25683224//25412662//24981863//22608085
chr11:5082417-5082418(-) m6A CDS//exon       25683224//24981863//22608085
chr11:5083422-5083423(-) m6A CDS//exon       24981863//22608085
chr11:5083489-5083490(-) m6A CDS//exon       24981863//22608085
chr11:5083517-5083518(-) m6A CDS//exon       24981863//22608085
chr11:5085978-5085979(-) m6A CDS//exon       24981863//22608085
chr11:5086034-5086035(-) m6A CDS//exon       24981863//22608085
chr11:5088026-5088027(-) m6A CDS       24981863//22608085
chr11:5091468-5091469(-) m6A CDS//intron       25683224//25569111//22608085
chr11:5091871-5091872(-) m6A CDS       25683224//25569111//22608085
chr11:5091894-5091895(-) m6A CDS       25683224//24981863//25569111//22608085
chr11:5091915-5091916(-) m6A CDS       25683224//24981863//25569111
chr11:5091949-5091950(-) m6A CDS       25683224//24981863//25569111
chr11:5091957-5091958(-) m6A CDS       25683224//24981863//25569111
chr11:5093688-5093689(-) m6A CDS//exon       24981863//25569111
chr11:5099235-5099236(-) m6A 5'UTR       25412662//24981863//25569111

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate Ewsr1
Nucleus Neuroblastoma cell line (N2A)     22406755

Interaction Network (The top 100 interactions):


Interactor1: mghv-miR-M1-7-5p
Interactor2: Ewsr1

Evidence Support:


Strong-Evidence Luciferase reporter assay//qRT-PCR//Western blot
Weak-Evidence qCLASH
Support Database ViRBase

References:


[1]PMID 31363027 Target region None
Source ViRBase Interactor1 expression Upregulation
Tissue or cell line B cells//NIH 3T12 cells Interactor2 expression Downregulation
Description Together, these data demonstrated that EWSR1 is strongly repressed by miR-7-5p both in vitro and in vivo.
[2]PMID 31393953 Target region None
Source ViRBase Interactor1 expression Upregulation
Tissue or cell line None Interactor2 expression Downregulation
Description QCLASH-identified targeting miRNAs were: miR-8-5p for Ctsl, miR-7-5p for Ewsr1, miR-7-5p for Ifitm3, and miR-12-3p for Foxj3.

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