Detail Information

Basic Information:


  VIRBase ID:  

VHID00519198

  Virus:  

Human herpesvirus 5 strain AD169

  Host:  

Homo sapiens

  Confidence Score:  

0.7311

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-US25-1-5p:           CES1P1:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hcmv-miR-US25-1-5p CES1P1
miRBase
Accession/Entrez ID		 MIMAT0001581 51716
Organism Human herpesvirus 5 strain AD169 Homo sapiens
Category miRNA pseudo
Alias - CES1A2//CES1A3//CES4//CESR//PCE-3

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate CES1P1
Exosome Blood     -

Related Drug Information:


Resource Symbol Drug Name PubChem
ID		 Function
ncDR CES1P1
cis-Diaminedichloroplatinum 2767 Drug sensitive
Resource Symbol Drug Name PubChem
ID		 Function Link  
RNAInter CES1P1
cis-Diaminedichloroplatinum 2767 Drug interaction    RC00000011

Interaction Network (The top 100 interactions):


Interactor1: hcmv-miR-US25-1-5p
Interactor2: CES1P1

Evidence Support:


Strong-Evidence RISC-IP
Support Database ViRBase

References:


PMID 20585629 Target region 5'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line HEK293 cells Interactor2 expression None
Description Here, we identify cellular transcript targets of one of the most highly expressed HCMV encoded miRNAs, miR-US25-1, using a recently developed biochemical approach called RISC immunoprecipitation. Strikingly, the majority of identified transcripts contained miR-US25-1 target sites within the 5'UTR rather than the 3'UTR.

Starting a new search, please wait ...