Basic Information:

  VIRBase ID:  

VHID00517135

  Virus:  

Human herpesvirus 5 strain AD169

  Host:  

Homo sapiens

  Confidence Score:  

0.7311

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-US25-1-5p:  MIMAT0001581          SAMD9L:  NM_001303498     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hcmv-miR-US25-1-5p	SAMD9L
miRBase Accession/Entrez ID	MIMAT0001581	219285
Organism	Human herpesvirus 5 strain AD169	Homo sapiens
Category	miRNA	mRNA
Alias	-	ATXPC//C7orf6//DRIF2//M7MLS1//UEF1

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	SAMD9L	chr7:92760666-92760667(-) m6A CDS       28052920 chr7:92760725-92760726(-) m6A CDS       28052920 chr7:92760830-92760831(-) m6A CDS       24981863//28052920//27371828 chr7:92760901-92760902(-) m6A CDS       24981863//28052920 chr7:92760946-92760947(-) m6A CDS       24981863 chr7:92761030-92761031(-) m6A CDS       24981863 chr7:92761060-92761061(-) m6A CDS       24981863 chr7:92761144-92761145(-) m6A CDS       24981863//28052920 chr7:92761172-92761173(-) m6A CDS       24981863//28052920 chr7:92761235-92761236(-) m6A CDS       24981863//28052920 chr7:92761258-92761259(-) m6A CDS       24981863//28052920 chr7:92761369-92761370(-) m6A CDS//intron       24981863//28052920 chr7:92761575-92761576(-) m6A CDS//intron       24981863//28052920 chr7:92761606-92761607(-) m6A CDS//intron       24981863//28052920 chr7:92761748-92761749(-) m6A CDS//intron       24981863//28052920//27371828 chr7:92761755-92761756(-) m6A CDS//intron       24981863//28052920//27371828 chr7:92761763-92761764(-) m6A CDS//intron       24981863//28052920//27371828 chr7:92761776-92761777(-) m6A CDS//intron       24981863//28052920//27371828 chr7:92761865-92761866(-) m6A CDS//intron       24209618//24981863//28052920//27371828//22575960 chr7:92761871-92761872(-) m6A CDS//intron       24209618//24981863//28052920//27371828//22575960 chr7:92761973-92761974(-) m6A CDS//intron       24209618//24981863//28052920//27371828//22575960 chr7:92761991-92761992(-) m6A CDS//intron       24209618//24981863//28052920//27371828//22575960 chr7:92762014-92762015(-) m6A CDS//intron       24209618//24981863//28052920//27371828//22575960 chr7:92762087-92762088(-) m6A CDS//intron       24981863//28052920//22575960 chr7:92762133-92762134(-) m6A CDS//intron       24981863//28052920//22575960 chr7:92762158-92762159(-) m6A CDS//intron       24981863//28052920//22575960 chr7:92762175-92762176(-) m6A CDS//intron       24981863//28052920//22575960 chr7:92762198-92762199(-) m6A CDS//intron       24981863//28052920 chr7:92762287-92762288(-) m6A CDS//intron       24981863//28052920 chr7:92762364-92762365(-) m6A CDS//intron       24981863 chr7:92762388-92762389(-) m6A CDS//intron       24981863 chr7:92762399-92762400(-) m6A CDS//intron       24981863 chr7:92762416-92762417(-) m6A CDS//intron       24981863 chr7:92762551-92762552(-) m6A CDS//intron       24981863//28052920 chr7:92762589-92762590(-) m6A CDS//intron       24981863//28052920 chr7:92762630-92762631(-) m6A CDS//intron       24981863//28052920 chr7:92762639-92762640(-) m6A CDS//intron       24981863//28052920 chr7:92762668-92762669(-) m6A CDS//intron       24981863//28052920 chr7:92762689-92762690(-) m6A CDS//intron       24981863//28052920 chr7:92762726-92762727(-) m6A CDS//intron       24981863//28052920 chr7:92762771-92762772(-) m6A CDS//intron       28052920 chr7:92762790-92762791(-) m6A CDS//intron       - chr7:92762863-92762864(-) m6A CDS//intron       - chr7:92762973-92762974(-) m6A CDS//intron       28052920 chr7:92762978-92762979(-) m6A CDS//intron       28052920 chr7:92763002-92763003(-) m6A CDS//intron       24981863//28052920 chr7:92763014-92763015(-) m6A CDS//intron       24981863//28052920 chr7:92763094-92763095(-) m6A CDS//intron       24981863//28052920 chr7:92763146-92763147(-) m6A CDS//intron       24981863 chr7:92763173-92763174(-) m6A CDS//intron       24981863 chr7:92763194-92763195(-) m6A CDS//intron       24981863//28052920 chr7:92763229-92763230(-) m6A CDS//intron       24981863//28052920 chr7:92763269-92763270(-) m6A CDS//intron       24981863//28052920 chr7:92763285-92763286(-) m6A CDS//intron       24981863//28052920 chr7:92763415-92763416(-) m6A CDS//intron       24981863 chr7:92763431-92763432(-) m6A CDS//intron       24981863 chr7:92763439-92763440(-) m6A CDS//intron       24981863 chr7:92763536-92763537(-) m6A CDS//intron       24981863 chr7:92764004-92764005(-) m6A CDS//intron       24981863 chr7:92764064-92764065(-) m6A CDS//intron       24981863//28052920 chr7:92764070-92764071(-) m6A CDS//intron       24981863//28052920 chr7:92764084-92764085(-) m6A CDS//intron       24981863//28052920 chr7:92764099-92764100(-) m6A CDS//intron       24981863//28052920 chr7:92764556-92764557(-) m6A CDS//intron       24981863 chr7:92764649-92764650(-) m6A CDS//intron       24981863//28052920 chr7:92764665-92764666(-) m6A CDS//intron       24981863//28052920 chr7:92764673-92764674(-) m6A CDS//intron       24981863//28052920 chr7:92764725-92764726(-) m6A CDS//intron       24981863//28052920 chr7:92764747-92764748(-) m6A CDS//intron       24981863//28052920 chr7:92764807-92764808(-) m6A CDS//intron       24981863//28052920 chr7:92764813-92764814(-) m6A CDS//intron       24981863//28052920 chr7:92764837-92764838(-) m6A CDS       24981863//28052920 chr7:92764894-92764895(-) m6A CDS       24981863//28052920 chr7:92764969-92764970(-) m6A CDS       24981863//28052920 chr7:92764987-92764988(-) m6A CDS       24981863//28052920//22575960 chr7:92764992-92764993(-) m6A CDS       24981863//28052920//22575960 chr7:92765002-92765003(-) m6A CDS       24981863//28052920//22575960 chr7:92765020-92765021(-) m6A CDS       24981863//28052920//27773535//22575960 chr7:92765123-92765124(-) m6A CDS       24209618//24981863//28052920//22575960 chr7:92765207-92765208(-) m6A CDS       24981863//28052920 chr7:92765241-92765242(-) m6A CDS       24981863//28052920 chr7:92765246-92765247(-) m6A CDS       24981863//28052920 chr7:92765275-92765276(-) m6A CDS       24981863//28052920 chr7:92775294-92775295(-) m6A 5'UTR//exon//intron       - chr7:92777574-92777575(-) m6A 5'UTR//exon       24981863 chr7:92777652-92777653(-) m6A 5'UTR//exon       24981863 chr7:92777659-92777660(-) m6A 5'UTR//exon       24981863

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	SAMD9L	Cytosol HeLa-S3 cells     - Exosome Blood     -

Interaction Network (The top 100 interactions):

Interactor1: hcmv-miR-US25-1-5p
Interactor2: SAMD9L

Evidence Support:

Strong-Evidence	RISC-IP
Support Database	ViRBase

References:

PMID	20585629	Target region	5'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	HEK293 cells	Interactor2 expression	None
Description	Here, we identify cellular transcript targets of one of the most highly expressed HCMV encoded miRNAs, miR-US25-1, using a recently developed biochemical approach called RISC immunoprecipitation. Strikingly, the majority of identified transcripts contained miR-US25-1 target sites within the 5'UTR rather than the 3'UTR.