Detail Information

Basic Information:


  VIRBase ID:  

VHID00516114

  Virus:  

Human herpesvirus 5 strain AD169

  Host:  

Homo sapiens

  Confidence Score:  

0.7311

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-US25-1-5p:           AMER1:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hcmv-miR-US25-1-5p AMER1
miRBase
Accession/Entrez ID		 MIMAT0001581 139285
Organism Human herpesvirus 5 strain AD169 Homo sapiens
Category miRNA mRNA
Alias - FAM123B//OSCS//WTX

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR AMER1
chrX:63421897(-) A-I      intronic

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase AMER1
chrX:63405143-63405144(-) m6A 3'UTR       24284625
chrX:63405249-63405250(-) m6A 3'UTR       24284625
chrX:63407465-63407466(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//27773535//27371828//22608085
chrX:63407510-63407511(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//27773535//27371828//22608085
chrX:63407563-63407564(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//27773535//22608085
chrX:63407595-63407596(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//22608085
chrX:63407808-63407809(-) m6A 3'UTR//intron       24284625//25456834//24981863//22608085
chrX:63407814-63407815(-) m6A 3'UTR//intron       24284625//25456834
chrX:63407887-63407888(-) m6A 3'UTR//intron       -
chrX:63408474-63408475(-) m6A 3'UTR//intron       24284625
chrX:63408754-63408755(-) m6A 3'UTR//intron       -
chrX:63409254-63409255(-) m6A 3'UTR//intron       -
chrX:63409295-63409296(-) m6A 3'UTR//intron       -
chrX:63409342-63409343(-) m6A 3'UTR//intron       24981863
chrX:63409734-63409735(-) m6A 3'UTR//intron       24284625
chrX:63409771-63409772(-) m6A CDS//intron       24284625
chrX:63410224-63410225(-) m6A CDS//intron       24284625//24209618//24981863//27773535
chrX:63410313-63410314(-) m6A CDS//intron       24284625//24209618//25456834//24981863//27371828//22608085
chrX:63410338-63410339(-) m6A CDS//intron       24284625//24209618//25456834//24981863//27371828//22608085
chrX:63410465-63410466(-) m6A CDS//intron       24284625//25456834//24981863//27371828//22575960//22608085
chrX:63410544-63410545(-) m6A CDS//intron       24284625//22608085
chrX:63410622-63410623(-) m6A CDS//intron       24284625//24209618
chrX:63410770-63410771(-) m6A CDS//intron       24284625//24981863//27371828//22608085
chrX:63410824-63410825(-) m6A CDS       24284625//24981863//27371828//27773536//22608085
chrX:63410974-63410975(-) m6A CDS       -
chrX:63411044-63411045(-) m6A CDS       24284625//24981863
chrX:63411076-63411077(-) m6A CDS       24284625//24209618//24981863//22608085
chrX:63411085-63411086(-) m6A CDS       24284625//24209618//24981863//22608085
chrX:63411149-63411150(-) m6A CDS       24284625//24209618//25456834//24981863//22608085
chrX:63411239-63411240(-) m6A CDS       24284625//24209618//25456834//24981863//27371828//22608085
chrX:63411254-63411255(-) m6A CDS       24284625//24209618//25456834//24981863//27371828//22608085
chrX:63411293-63411294(-) m6A CDS       24284625//24209618//24981863//27371828//22608085
chrX:63411468-63411469(-) m6A CDS       24284625
chrX:63411500-63411501(-) m6A CDS       24284625//24981863//22608085
chrX:63411544-63411545(-) m6A CDS       24284625//24981863//22608085
chrX:63411616-63411617(-) m6A CDS       24284625//24209618//24981863//22608085
chrX:63411673-63411674(-) m6A CDS       24284625//24209618//24981863//22608085
chrX:63411810-63411811(-) m6A CDS       24284625//22575960//22608085
chrX:63411901-63411902(-) m6A CDS       24284625//24981863//27773535//22608085
chrX:63411932-63411933(-) m6A CDS       24284625//24981863//27773535//22608085
chrX:63411961-63411962(-) m1A CDS       26863196
chrX:63411985-63411986(-) m1A CDS       26863196
chrX:63412009-63412010(-) m1A CDS       26863196
chrX:63412018-63412019(-) m1A CDS       26863196
chrX:63412100-63412101(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chrX:63412111-63412112(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chrX:63412141-63412142(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chrX:63412153-63412154(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chrX:63412159-63412160(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chrX:63412164-63412165(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chrX:63412246-63412247(-) m6A CDS       24284625//24209618//24981863//27773535//22608085
chrX:63412270-63412271(-) m6A CDS       24284625//24981863//27773535//22608085
chrX:63412301-63412302(-) m6A CDS       24284625//24981863//27773535//22608085
chrX:63412386-63412387(-) m6A CDS       24284625//24981863//27773535
chrX:63412434-63412435(-) m6A CDS       24284625//27371828
chrX:63412508-63412509(-) m6A CDS       24284625//27371828
chrX:63412733-63412734(-) m6A CDS       22608085
chrX:63412751-63412752(-) m6A CDS       24284625//22608085
chrX:63412826-63412827(-) m6A CDS       24284625//24209618//25456834//22608085
chrX:63412883-63412884(-) m6A CDS       24284625//24209618//25456834//24981863//22608085
chrX:63412992-63412993(-) m6A CDS       24284625//25456834//24981863//27371828//22608085
chrX:63413003-63413004(-) m6A CDS       24284625//25456834//24981863//27371828//22608085
chrX:63413049-63413050(-) m6A CDS       24284625//24981863//27371828//22608085
chrX:63413074-63413075(-) m6A CDS       24284625//24981863//27371828//22608085
chrX:63413100-63413101(-) m6A CDS       24284625//24981863//27371828//22608085
chrX:63413159-63413160(-) m6A CDS       24284625//27773535
chrX:63425463-63425464(-) m6A 5'UTR       27371828
chrX:63425481-63425482(-) m6A 5'UTR       27371828

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate AMER1
Exosome Blood     -
Nucleus HeLa-S3 cells     -

Interaction Network (The top 100 interactions):


Interactor1: hcmv-miR-US25-1-5p
Interactor2: AMER1

Evidence Support:


Strong-Evidence RISC-IP
Support Database ViRBase

References:


PMID 20585629 Target region 5'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line HEK293 cells Interactor2 expression None
Description Here, we identify cellular transcript targets of one of the most highly expressed HCMV encoded miRNAs, miR-US25-1, using a recently developed biochemical approach called RISC immunoprecipitation. Strikingly, the majority of identified transcripts contained miR-US25-1 target sites within the 5'UTR rather than the 3'UTR.

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