Basic Information:
VIRBase ID: VHID00516018
Virus: Human herpesvirus 5 strain AD169
Host: Homo sapiens
Confidence Score: 0.7951
Interaction Type: Virus-Host interaction
Predicted Binding:
* It may take a few minutes to display results.
RNA Editing:
Resource
Symbol
Editing Position
Change
Genetic Region
RADAR
UBLCP1
Resource
Symbol
Editing Position
Change
SeqReg
exReg
PMID
DARNED
UBLCP1
RNA Modification:
Resource
Symbol
ModificationPosition
Type
Genomic Context
PMID
RMBase
UBLCP1
RNA Localization:
Resource
Symbol
Subcellular Localization
Tissue or Cell Line
PMID
RNALocate
UBLCP1
Interaction Network (The top 100 interactions) :
Interactor1: hcmv-miR-US25-1-5p
Interactor2: UBLCP1
Evidence Support:
Strong-Evidence
RISC-IP
Prediction-Evidence
miRanda//PITA//Targetscan
Support Database
ViRBase//VmiReg
References:
PMID
20585629
Target region
5'UTR
Source
ViRBase//VmiReg
Interactor1 expression
None
Tissue or cell line
HEK293 cells
Interactor2 expression
None
Description
Here, we identify cellular transcript targets of one of the most highly expressed HCMV encoded miRNAs, miR-US25-1, using a recently developed biochemical approach called RISC immunoprecipitation. Strikingly, the majority of identified transcripts contained miR-US25-1 target sites within the 5'UTR rather than the 3'UTR.