Detail Information

Basic Information:


  VIRBase ID:  

VHID00515582

  Virus:  

Human herpesvirus 5 strain AD169

  Host:  

Homo sapiens

  Confidence Score:  

0.7311

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-US25-1-5p:           BTBD11:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hcmv-miR-US25-1-5p BTBD11
miRBase
Accession/Entrez ID		 MIMAT0001581 121551
Organism Human herpesvirus 5 strain AD169 Homo sapiens
Category miRNA mRNA
Alias - ABTB2B

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR BTBD11
chr12:107935901(+) A-I      intronic
chr12:107935916(+) A-I      intronic
chr12:107767144(+) A-I      intronic
chr12:107935942(+) A-I      intronic
chr12:107935949(+) A-I      intronic
chr12:107935911(+) A-I      intronic
chr12:107935968(+) A-I      intronic
chr12:107935969(+) A-I      intronic
chr12:107767145(+) A-I      intronic
chr12:107918841(+) A-I      intronic
chr12:107728983(+) A-I      intronic
chr12:107728989(+) A-I      intronic
chr12:107940818(+) A-I      intronic
chr12:107756555(+) A-I      intronic
chr12:107940819(+) A-I      intronic
chr12:107728984(+) A-I      intronic
chr12:107835637(+) A-I      intronic
chr12:107939119(+) A-I      intronic
chr12:108023141(+) A-I      intronic
chr12:107744067(+) A-I      intronic
chr12:107826813(+) A-I      intronic
chr12:107940824(+) A-I      intronic
chr12:108037688(+) A-I      intronic
chr12:107756558(+) A-I      intronic
chr12:108049869(+) A-I      intronic
chr12:107940916(+) A-I      intronic
chr12:107821285(+) A-I      intronic
chr12:107728867(+) A-I      intronic
chr12:107754635(+) A-I      intronic
chr12:108022939(+) A-I      intronic
chr12:108049845(+) A-I      intronic
chr12:108023145(+) A-I      intronic
chr12:107781850(+) A-I      intronic
chr12:107983708(+) A-I      intronic
chr12:108016359(+) A-I      intronic
chr12:108037077(+) A-I      intronic
chr12:108037137(+) A-I      intronic
chr12:107897349(+) A-I      intronic
chr12:108049957(+) A-I      intronic
chr12:107753266(+) A-I      intronic
chr12:108048176(+) A-I      intronic
chr12:107754608(+) A-I      intronic
chr12:107809224(+) A-I      intronic
chr12:107751281(+) A-I      intronic
chr12:108040956(+) A-I      intronic
chr12:108050765(+) A-I      intronic
chr12:107809231(+) A-I      intronic
chr12:108037602(+) A-I      intronic
chr12:108049883(+) A-I      intronic
chr12:108023125(+) A-I      intronic

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase BTBD11
chr12:107712259-107712260(+) m6A 5'UTR       24981863
chr12:107712272-107712273(+) m6A 5'UTR       24981863
chr12:107712351-107712352(+) m6A 5'UTR       24981863
chr12:107712412-107712413(+) m6A 5'UTR       24981863
chr12:107712503-107712504(+) m6A 5'UTR       24981863
chr12:107712625-107712626(+) m6A 5'UTR       24981863//27371828//22608085
chr12:107712772-107712773(+) m6A CDS       25456834//24981863//27371828//22608085
chr12:107712796-107712797(+) m6A CDS       25456834//24981863//27371828//22608085
chr12:107712943-107712944(+) m6A CDS       25456834//24981863//27371828//22608085
chr12:107712958-107712959(+) m6A CDS       25456834//24981863//27371828//22608085
chr12:107712994-107712995(+) m6A CDS       25456834//24981863//27371828//22608085
chr12:107713014-107713015(+) m6A CDS       25456834//24981863//27371828//22608085
chr12:107713381-107713382(+) m6A CDS       24981863
chr12:107713456-107713457(+) m6A CDS       24981863
chr12:107714400-107714401(+) m6A CDS//intron       27371828
chr12:107914281-107914282(+) m6A CDS//intron       27371828
chr12:108051337-108051338(+) m6A CDS       24981863//22608085
chr12:108051402-108051403(+) m6A CDS       25456834//24981863//22608085
chr12:108051424-108051425(+) m6A CDS       25456834//24981863//22608085
chr12:108051525-108051526(+) m6A 3'UTR       25456834//24981863//26404942//22608085
chr12:108051561-108051562(+) m6A 3'UTR       25456834//24981863//26404942//22608085
chr12:108051567-108051568(+) m6A 3'UTR       25456834//24981863//26404942//22608085
chr12:108051643-108051644(+) m6A 3'UTR       25456834//24981863//26404942//22608085
chr12:108051650-108051651(+) m6A 3'UTR       25456834//24981863//26404942//22608085
chr12:108051707-108051708(+) m6A 3'UTR       25456834//24981863//26404942//22608085
chr12:108051743-108051744(+) m6A 3'UTR       25456834//24981863//26404942//22608085
chr12:108051751-108051752(+) m6A 3'UTR       25456834//24981863//26404942//22608085
chr12:108051767-108051768(+) m6A 3'UTR       25456834//24981863//26404942//22608085
chr12:108051834-108051835(+) m6A 3'UTR       25456834//24981863//26404942//22608085
chr12:108051878-108051879(+) m6A 3'UTR       25456834//24981863//26404942//22608085
chr12:108051979-108051980(+) m6A 3'UTR       25456834//24981863//26404942//22608085
chr12:108052007-108052008(+) m6A 3'UTR       25456834//24981863//22608085
chr12:108052855-108052856(+) m6A 3'UTR       24981863//22608085
chr12:108052883-108052884(+) m6A 3'UTR       24981863//22608085
chr12:108052904-108052905(+) m6A 3'UTR       24981863//22608085
chr12:108052941-108052942(+) m6A 3'UTR       24981863
chr12:108052958-108052959(+) m6A 3'UTR       24981863
chr12:108053126-108053127(+) m6A 3'UTR       24981863
chr12:108053163-108053164(+) m6A 3'UTR       24981863
chr12:108053169-108053170(+) m6A 3'UTR       24981863

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate BTBD11
Cytosol HCC cell line (HepG2)     -
Exosome Blood     -
Nucleus HCC cell line (HepG2)     -

Interaction Network (The top 100 interactions):


Interactor1: hcmv-miR-US25-1-5p
Interactor2: BTBD11

Evidence Support:


Strong-Evidence RISC-IP
Support Database ViRBase

References:


PMID 20585629 Target region 5'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line HEK293 cells Interactor2 expression None
Description Here, we identify cellular transcript targets of one of the most highly expressed HCMV encoded miRNAs, miR-US25-1, using a recently developed biochemical approach called RISC immunoprecipitation. Strikingly, the majority of identified transcripts contained miR-US25-1 target sites within the 5'UTR rather than the 3'UTR.

Starting a new search, please wait ...