Detail Information

Basic Information:


  VIRBase ID:  

VHID00514913

  Virus:  

Human herpesvirus 5 strain AD169

  Host:  

Homo sapiens

  Confidence Score:  

0.7311

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-US25-1-5p:           YIF1B:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hcmv-miR-US25-1-5p YIF1B
miRBase
Accession/Entrez ID		 MIMAT0001581 90522
Organism Human herpesvirus 5 strain AD169 Homo sapiens
Category miRNA mRNA
Alias - FinGER8//KABAMAS

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR YIF1B
chr19:38802655(-) A-I      intronic
chr19:38804959(-) A-I      intronic
chr19:38805100(-) A-I      intronic
chr19:38804734(-) A-I      intronic
chr19:38805299(-) A-I      intronic
chr19:38805227(-) A-I      intronic
chr19:38805114(-) A-I      intronic
chr19:38805048(-) A-I      intronic
chr19:38804967(-) A-I      intronic
chr19:38804895(-) A-I      intronic
chr19:38804804(-) A-I      intronic
chr19:38804771(-) A-I      intronic
chr19:38802532(-) A-I      intronic
chr19:38804731(-) A-I      intronic
chr19:38804678(-) A-I      intronic
chr19:38804083(-) A-I      intronic
chr19:38803729(-) A-I      intronic
chr19:38803703(-) A-I      intronic
chr19:38804009(-) A-I      intronic
chr19:38803888(-) A-I      intronic
chr19:38803873(-) A-I      intronic
chr19:38802881(-) A-I      intronic
chr19:38803664(-) A-I      intronic
chr19:38803644(-) A-I      intronic
chr19:38805822(-) A-I      intronic
chr19:38805884(-) A-I      intronic
chr19:38802705(-) A-I      intronic
chr19:38802717(-) A-I      intronic
chr19:38803767(-) A-I      intronic
chr19:38802674(-) A-I      intronic
chr19:38802650(-) A-I      intronic
chr19:38802637(-) A-I      intronic
chr19:38802625(-) A-I      intronic
chr19:38802615(-) A-I      intronic
chr19:38803639(-) A-I      intronic
chr19:38802571(-) A-I      intronic
chr19:38802545(-) A-I      intronic
chr19:38797008(-) A-I      intronic
chr19:38797003(-) A-I      intronic
chr19:38796996(-) A-I      intronic
chr19:38796694(-) A-I      intronic
chr19:38796676(-) A-I      intronic
chr19:38803793(-) A-I      intronic
chr19:38803768(-) A-I      intronic
chr19:38803762(-) A-I      intronic
chr19:38803760(-) A-I      intronic
chr19:38803759(-) A-I      intronic
chr19:38803732(-) A-I      intronic
chr19:38804742(-) A-I      intronic
chr19:38805534(-) A-I      intronic
chr19:38805398(-) A-I      intronic
chr19:38805369(-) A-I      intronic
chr19:38805350(-) A-I      intronic
chr19:38805346(-) A-I      intronic
chr19:38803756(-) A-I      intronic
chr19:38805108(-) A-I      intronic
chr19:38805133(-) A-I      intronic
chr19:38801770(-) A-I      intronic
chr19:38802495(-) A-I      intronic
chr19:38802473(-) A-I      intronic
chr19:38796600(-) A-I      intronic
chr19:38805076(-) A-I      intronic
chr19:38802557(-) A-I      intronic
chr19:38802829(-) A-I      intronic
chr19:38805654(-) A-I      intronic
chr19:38804733(-) A-I      intronic
chr19:38804902(-) A-I      intronic
chr19:38805773(-) A-I      intronic
chr19:38797012(-) A-I      intronic
chr19:38803659(-) A-I      intronic
chr19:38796781(-) A-I      intronic
chr19:38805716(-) A-I      intronic
chr19:38801832(-) A-I      intronic
chr19:38805391(-) A-I      intronic
chr19:38801913(-) A-I      intronic
chr19:38805640(-) A-I      intronic
chr19:38804803(-) A-I      intronic
chr19:38804037(-) A-I      intronic
chr19:38805175(-) A-I      intronic
chr19:38805431(-) A-I      intronic
chr19:38805696(-) A-I      intronic
chr19:38797078(-) A-I      intronic
chr19:38801921(-) A-I      intronic
chr19:38802574(-) A-I      intronic
chr19:38803624(-) A-I      intronic
chr19:38805339(-) A-I      intronic
chr19:38802819(-) A-I      intronic
chr19:38802482(-) A-I      intronic
chr19:38805833(-) A-I      intronic
chr19:38804758(-) A-I      intronic
chr19:38805226(-) A-I      intronic
chr19:38804171(-) A-I      intronic
chr19:38797097(-) A-I      intronic
chr19:38802945(-) A-I      intronic
chr19:38805846(-) A-I      intronic
chr19:38801779(-) A-I      intronic
chr19:38805528(-) A-I      intronic
chr19:38802971(-) A-I      intronic
chr19:38805051(-) A-I      intronic
chr19:38802513(-) A-I      intronic
chr19:38805392(-) A-I      intronic
chr19:38804931(-) A-I      intronic
chr19:38805356(-) A-I      intronic
chr19:38804872(-) A-I      intronic
chr19:38804762(-) A-I      intronic
chr19:38804794(-) A-I      intronic
chr19:38805212(-) A-I      intronic
chr19:38803765(-) A-I      intronic
chr19:38805655(-) A-I      intronic
chr19:38801881(-) A-I      intronic
chr19:38797039(-) A-I      intronic
chr19:38802474(-) A-I      intronic
chr19:38797083(-) A-I      intronic
chr19:38802904(-) A-I      intronic
chr19:38804774(-) A-I      intronic
chr19:38805665(-) A-I      intronic
chr19:38802981(-) A-I      intronic
chr19:38802935(-) A-I      intronic
chr19:38805480(-) A-I      intronic
chr19:38805005(-) A-I      intronic
chr19:38802807(-) A-I      intronic
chr19:38805731(-) A-I      intronic
chr19:38803730(-) A-I      intronic
chr19:38803864(-) A-I      intronic
chr19:38805859(-) A-I      intronic
chr19:38796787(-) A-I      intronic
chr19:38802962(-) A-I      intronic
chr19:38797016(-) A-I      intronic
chr19:38801818(-) A-I      intronic
chr19:38802493(-) A-I      intronic
chr19:38797577(-) A-I      Syn:Gly->Gly
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED YIF1B
chr19:38803652(-) A-I intron -    22327324
chr19:38804708(-) A-I intron -    22327324
chr19:38805356(-) A-I intron -    22327324
chr19:38805392(-) A-I intron -    22327324
chr19:38805833(-) A-I intron -    22327324
chr19:38796925(-) A-G intron -    22484847
chr19:38796990(-) A-G intron -    22484847
chr19:38797097(-) A-G intron -    22484847
chr19:38801818(-) A-G intron -    22484847
chr19:38801832(-) A-G intron -    22484847
chr19:38802474(-) A-G intron -    22484847
chr19:38802494(-) A-G intron -    22484847
chr19:38802513(-) A-G intron -    22484847
chr19:38802517(-) A-G intron -    22484847
chr19:38802829(-) A-G intron -    22484847
chr19:38802945(-) A-G intron -    22484847
chr19:38803652(-) A-G intron -    22484847
chr19:38803657(-) A-G intron -    22484847
chr19:38803720(-) A-G intron -    22484847
chr19:38803730(-) A-G intron -    22484847
chr19:38803838(-) A-G intron -    22484847
chr19:38804758(-) A-G intron -    22484847
chr19:38804973(-) A-G intron -    22484847
chr19:38805062(-) A-G intron -    22484847
chr19:38805392(-) A-G intron -    22484847
chr19:38805480(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase YIF1B
chr19:38795748-38795749(-) m6A 3'UTR       -
chr19:38795769-38795770(-) m6A 3'UTR//exon       24981863
chr19:38795776-38795777(-) m6A 3'UTR//exon       24981863
chr19:38795931-38795932(-) m6A 3'UTR//exon       24284625//27773536
chr19:38795977-38795978(-) m6A 3'UTR//exon       24284625//27773536
chr19:38796076-38796077(-) m6A 3'UTR//CDS//exon       27773536
chr19:38806108-38806109(-) m6A exon//intron       24981863
chr19:38806168-38806169(-) m6A exon//intron       24981863
chr19:38806295-38806296(-) m6A exon//intron       24981863//27773535
chr19:38806305-38806306(-) m6A exon//intron       24981863//27773535
chr19:38806393-38806394(-) m6A 5'UTR//exon//intron       24981863
chr19:38806584-38806585(-) m6A 5'UTR//intron       24981863
chr19:38807828-38807829(-) m6A 5'UTR       -
chr19:38807851-38807852(-) m6A 5'UTR       -

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate YIF1B
Chromatin K562 cells     -
Cytosol HeLa-S3 cells|K562 cells     -
Exosome Blood     -
Nucleolus K562 cells     -
Nucleoplasm K562 cells     -
Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):


Interactor1: hcmv-miR-US25-1-5p
Interactor2: YIF1B

Evidence Support:


Strong-Evidence RISC-IP
Support Database ViRBase

References:


PMID 20585629 Target region 5'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line HEK293 cells Interactor2 expression None
Description Here, we identify cellular transcript targets of one of the most highly expressed HCMV encoded miRNAs, miR-US25-1, using a recently developed biochemical approach called RISC immunoprecipitation. Strikingly, the majority of identified transcripts contained miR-US25-1 target sites within the 5'UTR rather than the 3'UTR.

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