Detail Information

Basic Information:


  VIRBase ID:  

VHID00514436

  Virus:  

Human herpesvirus 5 strain AD169

  Host:  

Homo sapiens

  Confidence Score:  

0.7311

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-US25-1-5p:           ZBED3:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hcmv-miR-US25-1-5p ZBED3
miRBase
Accession/Entrez ID		 MIMAT0001581 84327
Organism Human herpesvirus 5 strain AD169 Homo sapiens
Category miRNA mRNA
Alias - -

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR ZBED3
chr5:76377456(-) A-I      intronic
chr5:76377357(-) A-I      intronic
chr5:76378084(-) A-I      intronic
chr5:76377983(-) A-I      intronic
chr5:76377980(-) A-I      intronic
chr5:76377935(-) A-I      intronic
chr5:76377355(-) A-I      intronic
chr5:76377323(-) A-I      intronic
chr5:76377307(-) A-I      intronic
chr5:76377313(-) A-I      intronic
chr5:76377343(-) A-I      intronic
chr5:76377344(-) A-I      intronic
chr5:76378023(-) A-I      intronic
chr5:76378045(-) A-I      intronic
chr5:76377260(-) A-I      intronic
chr5:76377339(-) A-I      intronic
chr5:76378058(-) A-I      intronic
chr5:76377167(-) A-I      intronic
chr5:76377425(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED ZBED3
chr5:76377412(-) A-G intron -    22484847
chr5:76378053(-) A-G intron -    22484847
chr5:76378058(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase ZBED3
chr5:76369314-76369315(-) m6A 3'UTR       27773535
chr5:76369346-76369347(-) m6A 3'UTR       27773535
chr5:76369356-76369357(-) m6A 3'UTR       27773535
chr5:76369454-76369455(-) m6A 3'UTR       27773535
chr5:76369739-76369740(-) m6A 3'UTR       27773535
chr5:76369791-76369792(-) m6A 3'UTR       27773535
chr5:76369824-76369825(-) m6A 3'UTR       27773535
chr5:76369845-76369846(-) m6A 3'UTR       24284625//27773535
chr5:76369921-76369922(-) m6A 3'UTR       24284625//24981863//27773535
chr5:76369941-76369942(-) m6A 3'UTR       24284625//24981863//27773535
chr5:76370237-76370238(-) m6A 3'UTR       27773535
chr5:76370616-76370617(-) m6A 3'UTR       27773535
chr5:76370691-76370692(-) m6A 3'UTR       27773535
chr5:76370915-76370916(-) m6A 3'UTR       27773535
chr5:76370962-76370963(-) m6A 3'UTR       27773535
chr5:76371200-76371201(-) m6A 3'UTR       27773535
chr5:76371280-76371281(-) m6A 3'UTR       24981863//27773535
chr5:76371328-76371329(-) m6A 3'UTR       24981863//27773535
chr5:76371990-76371991(-) m6A 3'UTR       27773535
chr5:76372248-76372249(-) m6A 3'UTR       27773535
chr5:76372310-76372311(-) m6A 3'UTR       24284625//27773535
chr5:76372430-76372431(-) m6A 3'UTR       24284625//24981863//27773535
chr5:76372605-76372606(-) m6A 3'UTR       24284625//25456834//24981863//27773535//27371828//27773536//22575960//22608085
chr5:76372648-76372649(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960//22608085
chr5:76372654-76372655(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960//22608085
chr5:76372687-76372688(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960//22608085
chr5:76372693-76372694(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960//22608085
chr5:76372721-76372722(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960//22608085
chr5:76372801-76372802(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960//22608085
chr5:76372807-76372808(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960//22608085
chr5:76372926-76372927(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr5:76372937-76372938(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr5:76372971-76372972(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960//22608085
chr5:76373151-76373152(-) m6A CDS       24209618//25456834//24981863//27371828//27773536//22575960
chr5:76373301-76373302(-) m6A CDS       24981863//27371828//27773536//22575960
chr5:76373447-76373448(-) m6A CDS       24209618//27371828//27773536
chr5:76373619-76373620(-) m6A CDS       24209618//24981863//27371828//27773536//22575960
chr5:76373671-76373672(-) m6A CDS       24284625//24981863//27371828//27773536//22575960
chr5:76374459-76374460(-) m6A 5'UTR//intron       24284625//27773535//22575960
chr5:76374479-76374480(-) m6A 5'UTR//intron       24284625//27773535
chr5:76374531-76374532(-) m6A 5'UTR//intron       24284625
chr5:76374876-76374877(-) m6A exon//intron       24284625
chr5:76376340-76376341(-) m6A intron       22575960
chr5:76376389-76376390(-) m6A intron       22575960
chr5:76382980-76382981(-) m6A 5'UTR//exon       24284625//25456834
chr5:76383024-76383025(-) m6A 5'UTR//exon       24284625//25456834

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate ZBED3
Exosome Blood     -

Interaction Network (The top 100 interactions):


Interactor1: hcmv-miR-US25-1-5p
Interactor2: ZBED3

Evidence Support:


Strong-Evidence RISC-IP
Support Database ViRBase

References:


PMID 20585629 Target region 5'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line HEK293 cells Interactor2 expression None
Description Here, we identify cellular transcript targets of one of the most highly expressed HCMV encoded miRNAs, miR-US25-1, using a recently developed biochemical approach called RISC immunoprecipitation. Strikingly, the majority of identified transcripts contained miR-US25-1 target sites within the 5'UTR rather than the 3'UTR.

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