Detail Information

Basic Information:


  VIRBase ID:  

VHID00514158

  Virus:  

Human herpesvirus 5 strain AD169

  Host:  

Homo sapiens

  Confidence Score:  

0.7311

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-US25-1-5p:           FAM107B:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hcmv-miR-US25-1-5p FAM107B
miRBase
Accession/Entrez ID		 MIMAT0001581 83641
Organism Human herpesvirus 5 strain AD169 Homo sapiens
Category miRNA mRNA
Alias - C10orf45//HITS

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR FAM107B
chr10:14617425(-) A-I      intronic
chr10:14624544(-) A-I      intronic
chr10:14617384(-) A-I      intronic
chr10:14579734(-) A-I      intronic
chr10:14642903(-) A-I      intronic
chr10:14637604(-) A-I      intronic
chr10:14593363(-) A-I      intronic
chr10:14604017(-) A-I      intronic
chr10:14593394(-) A-I      intronic
chr10:14635657(-) A-I      intronic
chr10:14603857(-) A-I      intronic
chr10:14594606(-) A-I      intronic
chr10:14594610(-) A-I      intronic
chr10:14593317(-) A-I      intronic
chr10:14594667(-) A-I      intronic
chr10:14624553(-) A-I      intronic
chr10:14594728(-) A-I      intronic
chr10:14618302(-) A-I      intronic
chr10:14642829(-) A-I      intronic
chr10:14618343(-) A-I      intronic
chr10:14618346(-) A-I      intronic
chr10:14618442(-) A-I      intronic
chr10:14624556(-) A-I      intronic
chr10:14642823(-) A-I      intronic
chr10:14636441(-) A-I      intronic
chr10:14624560(-) A-I      intronic
chr10:14642777(-) A-I      intronic
chr10:14624465(-) A-I      intronic
chr10:14642747(-) A-I      intronic
chr10:14624468(-) A-I      intronic
chr10:14624472(-) A-I      intronic
chr10:14624473(-) A-I      intronic
chr10:14593228(-) A-I      intronic
chr10:14624481(-) A-I      intronic
chr10:14624893(-) A-I      intronic
chr10:14624504(-) A-I      intronic
chr10:14641636(-) A-I      intronic
chr10:14624541(-) A-I      intronic
chr10:14641634(-) A-I      intronic
chr10:14639935(-) A-I      intronic
chr10:14639837(-) A-I      intronic
chr10:14639825(-) A-I      intronic
chr10:14639821(-) A-I      intronic
chr10:14639764(-) A-I      intronic
chr10:14639703(-) A-I      intronic
chr10:14639691(-) A-I      intronic
chr10:14624548(-) A-I      intronic
chr10:14566124(-) A-I      intronic
chr10:14624880(-) A-I      intronic
chr10:14579752(-) A-I      intronic
chr10:14594746(-) A-I      intronic
chr10:14604003(-) A-I      intronic
chr10:14593371(-) A-I      intronic
chr10:14731876(-) A-I      intronic
chr10:14593381(-) A-I      intronic
chr10:14668683(-) A-I      intronic
chr10:14624571(-) A-I      intronic
chr10:14624581(-) A-I      intronic
chr10:14636446(-) A-I      intronic
chr10:14618522(-) A-I      intronic
chr10:14731879(-) A-I      intronic
chr10:14637522(-) A-I      intronic
chr10:14668641(-) A-I      intronic
chr10:14624610(-) A-I      intronic
chr10:14593386(-) A-I      intronic
chr10:14668686(-) A-I      intronic
chr10:14593423(-) A-I      intronic
chr10:14636283(-) A-I      intronic
chr10:14625039(-) A-I      intronic
chr10:14625003(-) A-I      intronic
chr10:14624936(-) A-I      intronic
chr10:14624928(-) A-I      intronic
chr10:14608961(-) A-I      intronic
chr10:14617429(-) A-I      intronic
chr10:14637521(-) A-I      intronic
chr10:14603856(-) A-I      intronic
chr10:14643057(-) A-I      intronic
chr10:14642753(-) A-I      intronic
chr10:14624922(-) A-I      intronic
chr10:14636391(-) A-I      intronic
chr10:14604057(-) A-I      intronic
chr10:14603895(-) A-I      intronic
chr10:14624557(-) A-I      intronic
chr10:14637603(-) A-I      intronic
chr10:14624648(-) A-I      intronic
chr10:14618322(-) A-I      intronic
chr10:14594745(-) A-I      intronic
chr10:14624998(-) A-I      intronic
chr10:14594618(-) A-I      intronic
chr10:14593245(-) A-I      intronic
chr10:14623731(-) A-I      intronic
chr10:14617381(-) A-I      intronic
chr10:14643038(-) A-I      intronic
chr10:14624828(-) A-I      intronic
chr10:14624555(-) A-I      intronic
chr10:14603922(-) A-I      intronic
chr10:14593271(-) A-I      intronic
chr10:14612679(-) A-I      intronic
chr10:14635617(-) A-I      intronic
chr10:14624937(-) A-I      intronic
chr10:14624999(-) A-I      intronic
chr10:14593285(-) A-I      intronic
chr10:14618431(-) A-I      intronic
chr10:14623695(-) A-I      intronic
chr10:14639783(-) A-I      intronic
chr10:14624551(-) A-I      intronic
chr10:14625048(-) A-I      intronic
chr10:14618321(-) A-I      intronic
chr10:14636288(-) A-I      intronic
chr10:14624820(-) A-I      intronic
chr10:14636408(-) A-I      intronic
chr10:14604064(-) A-I      intronic
chr10:14624819(-) A-I      intronic
chr10:14624445(-) A-I      intronic
chr10:14637592(-) A-I      intronic
chr10:14692517(-) A-I      intronic
chr10:14617308(-) A-I      intronic
chr10:14637624(-) A-I      intronic
chr10:14642736(-) A-I      intronic
chr10:14594773(-) A-I      intronic
chr10:14609044(-) A-I      intronic
chr10:14637625(-) A-I      intronic
chr10:14624487(-) A-I      intronic
chr10:14636387(-) A-I      intronic
chr10:14623807(-) A-I      intronic
chr10:14603846(-) A-I      intronic
chr10:14609095(-) A-I      intronic
chr10:14643055(-) A-I      intronic
chr10:14637517(-) A-I      intronic
chr10:14617474(-) A-I      intronic
chr10:14639780(-) A-I      intronic
chr10:14636421(-) A-I      intronic
chr10:14624657(-) A-I      intronic
chr10:14642750(-) A-I      intronic
chr10:14796043(-) A-I      intronic
chr10:14603989(-) A-I      intronic
chr10:14612628(-) A-I      intronic
chr10:14630223(-) A-I      intronic
chr10:14605609(-) A-I      intronic
chr10:14625017(-) A-I      intronic
chr10:14624840(-) A-I      intronic
chr10:14642965(-) A-I      intronic
chr10:14625002(-) A-I      intronic
chr10:14561836(-) A-I      3'UTR
chr10:14574725(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED FAM107B
chr10:14603846(-) A-I intron -    15342557
chr10:14603856(-) A-I intron -    15342557
chr10:14603857(-) A-I intron -    15342557
chr10:14603895(-) A-I intron -    15342557
chr10:14603922(-) A-I intron -    15342557
chr10:14603988(-) A-I intron -    15342557
chr10:14603989(-) A-I intron -    15342557
chr10:14604003(-) A-I intron -    15342557
chr10:14604057(-) A-I intron -    15342557
chr10:14604064(-) A-I intron -    15342557
chr10:14605573(-) A-I intron -    15342557
chr10:14605609(-) A-I intron -    15342557
chr10:14608961(-) A-I intron -    15342557
chr10:14609044(-) A-I intron -    15342557
chr10:14609095(-) A-I intron -    15342557
chr10:14609487(-) A-I intron -    15342557
chr10:14574725(-) A-I intron -    21960545
chr10:14641636(-) A-I intron -    21960545
chr10:14624445(-) A-G intron -    22484847
chr10:14624487(-) A-G intron -    22484847
chr10:14624553(-) A-G intron -    22484847
chr10:14624937(-) A-G intron -    22484847
chr10:14636283(-) A-G intron -    22484847
chr10:14636288(-) A-G intron -    22484847
chr10:14643038(-) A-G intron -    22484847
chr10:14643057(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase FAM107B
chr10:14561325-14561326(-) m6A 3'UTR       24284625//26404942
chr10:14561359-14561360(-) m6A 3'UTR       24284625//22608085
chr10:14561889-14561890(-) m6A 3'UTR       26404942
chr10:14561924-14561925(-) m6A 3'UTR       26404942
chr10:14562006-14562007(-) m6A 3'UTR       26404942
chr10:14562081-14562082(-) m6A 3'UTR       -
chr10:14562222-14562223(-) m6A 3'UTR       26404942
chr10:14562365-14562366(-) m6A 3'UTR       26404942
chr10:14562704-14562705(-) m6A 3'UTR       26404942//27773535
chr10:14562796-14562797(-) m6A 3'UTR       24284625//25456834//24981863//26404942//27773535//22608085
chr10:14562829-14562830(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr10:14562892-14562893(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr10:14562906-14562907(-) Gm 3'UTR       -
chr10:14562910-14562911(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr10:14562920-14562921(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr10:14562933-14562934(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr10:14562943-14562944(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr10:14562957-14562958(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr10:14563170-14563171(-) m6A 3'UTR//exon       24284625//24209618//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr10:14563223-14563224(-) m6A 3'UTR//CDS//exon       24284625//24209618//24981863//28052920//26404942//27773535//27371828//22608085
chr10:14563299-14563300(-) m6A 3'UTR//CDS//exon       24209618//24981863//28052920//26404942//27773535//22608085
chr10:14563944-14563945(-) Cm 3'UTR//CDS//exon       -
chr10:14563958-14563959(-) m6A 3'UTR//CDS//exon       24209618//24981863//28052920//27773535//22608085
chr10:14564000-14564001(-) m6A 3'UTR//CDS//exon       24981863//28052920//27773535
chr10:14564116-14564117(-) m6A exon//intron       27773535
chr10:14572350-14572351(-) m6A 3'UTR//CDS//exon       24981863//26404942//27773535
chr10:14572372-14572373(-) m6A 3'UTR//CDS//exon       24981863//26404942//27773535
chr10:14572382-14572383(-) m6A 3'UTR//CDS//exon       24981863//26404942//27773535
chr10:14572401-14572402(-) m6A 3'UTR//CDS//exon       24981863//26404942//27773535
chr10:14572419-14572420(-) m6A 3'UTR//CDS//exon       24981863//26404942//27773535
chr10:14572444-14572445(-) m6A 3'UTR//CDS//exon       24981863//26404942//27773535
chr10:14572483-14572484(-) m6A 3'UTR//5'UTR//CDS//exon       26404942//27773535
chr10:14574640-14574641(-) m6A 5'UTR//intron       27773535
chr10:14644551-14644552(-) m6A exon//intron       27773535
chr10:14644601-14644602(-) m6A exon//intron       27773535
chr10:14644744-14644745(-) m6A exon//intron       24981863//26404942
chr10:14644799-14644800(-) m6A exon//intron       24981863//26404942
chr10:14644808-14644809(-) m6A exon//intron       24981863//26404942

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate FAM107B
Cytosol HeLa-S3 cells     -
Exosome Blood     -
Nucleus HCC cell line (HepG2)|HeLa-S3 cells     -

Interaction Network (The top 100 interactions):


Interactor1: hcmv-miR-US25-1-5p
Interactor2: FAM107B

Evidence Support:


Strong-Evidence RISC-IP
Support Database ViRBase

References:


PMID 20585629 Target region 5'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line HEK293 cells Interactor2 expression None
Description Here, we identify cellular transcript targets of one of the most highly expressed HCMV encoded miRNAs, miR-US25-1, using a recently developed biochemical approach called RISC immunoprecipitation. Strikingly, the majority of identified transcripts contained miR-US25-1 target sites within the 5'UTR rather than the 3'UTR.

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