Detail Information

Basic Information:


  VIRBase ID:  

VHID00510113

  Virus:  

Human herpesvirus 5 strain AD169

  Host:  

Homo sapiens

  Confidence Score:  

0.7311

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-US25-1-5p:           LAMP3:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hcmv-miR-US25-1-5p LAMP3
miRBase
Accession/Entrez ID		 MIMAT0001581 27074
Organism Human herpesvirus 5 strain AD169 Homo sapiens
Category miRNA mRNA
Alias - CD208//DC LAMP//DC-LAMP//DCLAMP//LAMP//LAMP-3//TSC403

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR LAMP3
chr3:182848053(-) A-I      intronic
chr3:182846509(-) A-I      intronic
chr3:182846534(-) A-I      intronic
chr3:182848241(-) A-I      intronic
chr3:182848219(-) A-I      intronic
chr3:182864968(-) A-I      intronic
chr3:182864949(-) A-I      intronic
chr3:182864948(-) A-I      intronic
chr3:182864588(-) A-I      intronic
chr3:182864566(-) A-I      intronic
chr3:182848156(-) A-I      intronic
chr3:182867148(-) A-I      intronic
chr3:182846457(-) A-I      intronic
chr3:182864398(-) A-I      intronic
chr3:182845860(-) A-I      intronic
chr3:182845827(-) A-I      intronic
chr3:182855767(-) A-I      intronic
chr3:182865586(-) A-I      intronic
chr3:182855745(-) A-I      intronic
chr3:182855719(-) A-I      intronic
chr3:182855705(-) A-I      intronic
chr3:182855693(-) A-I      intronic
chr3:182855612(-) A-I      intronic
chr3:182844999(-) A-I      intronic
chr3:182854921(-) A-I      intronic
chr3:182854888(-) A-I      intronic
chr3:182842558(-) A-I      intronic
chr3:182842533(-) A-I      intronic
chr3:182865701(-) A-I      intronic
chr3:182848111(-) A-I      intronic
chr3:182855752(-) A-I      intronic
chr3:182841103(-) A-I      3'UTR
chr3:182841102(-) A-I      3'UTR
chr3:182841084(-) A-I      3'UTR
chr3:182841117(-) A-I      3'UTR
chr3:182841112(-) A-I      3'UTR
chr3:182841090(-) A-I      3'UTR
chr3:182841104(-) A-I      3'UTR
chr3:182845142(-) A-I      intronic
chr3:182846523(-) A-I      intronic
chr3:182845045(-) A-I      intronic
chr3:182845752(-) A-I      intronic
chr3:182845755(-) A-I      intronic
chr3:182864842(-) A-I      intronic
chr3:182865665(-) A-I      intronic
chr3:182851343(-) A-I      intronic
chr3:182848115(-) A-I      intronic
chr3:182845730(-) A-I      intronic
chr3:182857059(-) A-I      intronic
chr3:182865778(-) A-I      intronic
chr3:182874000(-) A-I      intronic
chr3:182847948(-) A-I      intronic
chr3:182845089(-) A-I      intronic
chr3:182845824(-) A-I      intronic
chr3:182846605(-) A-I      intronic
chr3:182844995(-) A-I      intronic
chr3:182841325(-) A-I      3'UTR
chr3:182841235(-) A-I      3'UTR
chr3:182845675(-) A-I      intronic
chr3:182846609(-) A-I      intronic
chr3:182865594(-) A-I      intronic
chr3:182846596(-) A-I      intronic
chr3:182844953(-) A-I      intronic
chr3:182857102(-) A-I      intronic
chr3:182846533(-) A-I      intronic
chr3:182842464(-) A-I      intronic
chr3:182855704(-) A-I      intronic
chr3:182851215(-) A-I      intronic
chr3:182844952(-) A-I      intronic
chr3:182855812(-) A-I      intronic
chr3:182855884(-) A-I      intronic
chr3:182845204(-) A-I      intronic
chr3:182845814(-) A-I      intronic
chr3:182851281(-) A-I      intronic
chr3:182848085(-) A-I      intronic
chr3:182845050(-) A-I      intronic
chr3:182845119(-) A-I      intronic
chr3:182865760(-) A-I      intronic
chr3:182862626(-) A-I      intronic
chr3:182846468(-) A-I      intronic
chr3:182846597(-) A-I      intronic
chr3:182855806(-) A-I      intronic
chr3:182842498(-) A-I      intronic
chr3:182864989(-) A-I      intronic
chr3:182857066(-) A-I      intronic
chr3:182845194(-) A-I      intronic
chr3:182845738(-) A-I      intronic
chr3:182846497(-) A-I      intronic
chr3:182846602(-) A-I      intronic
chr3:182846557(-) A-I      intronic
chr3:182851280(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED LAMP3
chr3:182844953(-) A-I intron -    22327324
chr3:182845194(-) A-I intron -    22327324
chr3:182845685(-) A-I intron -    22327324
chr3:182846533(-) A-I intron -    22327324
chr3:182846605(-) A-I intron -    22327324
chr3:182846609(-) A-I intron -    22327324
chr3:182844744(-) A-G intron -    22484847
chr3:182841207(-) G-A exon 3'UTR    22484847
chr3:182842464(-) A-G intron -    22484847
chr3:182842498(-) A-G intron -    22484847
chr3:182844952(-) A-G intron -    22484847
chr3:182844953(-) A-G intron -    22484847
chr3:182844995(-) A-G intron -    22484847
chr3:182845045(-) A-G intron -    22484847
chr3:182845050(-) A-G intron -    22484847
chr3:182845089(-) A-G intron -    22484847
chr3:182845119(-) A-G intron -    22484847
chr3:182845141(-) A-G intron -    22484847
chr3:182845142(-) A-G intron -    22484847
chr3:182845150(-) A-G intron -    22484847
chr3:182845194(-) A-G intron -    22484847
chr3:182845204(-) A-G intron -    22484847
chr3:182845675(-) A-G intron -    22484847
chr3:182845730(-) A-G intron -    22484847
chr3:182845738(-) A-G intron -    22484847
chr3:182845752(-) A-G intron -    22484847
chr3:182845755(-) A-G intron -    22484847
chr3:182845814(-) A-G intron -    22484847
chr3:182845824(-) A-G intron -    22484847
chr3:182845935(-) G-T intron -    22484847
chr3:182846468(-) A-G intron -    22484847
chr3:182846494(-) A-G intron -    22484847
chr3:182846497(-) A-G intron -    22484847
chr3:182846523(-) A-G intron -    22484847
chr3:182846533(-) A-G intron -    22484847
chr3:182846557(-) A-G intron -    22484847
chr3:182846596(-) A-G intron -    22484847
chr3:182846597(-) A-G intron -    22484847
chr3:182846602(-) A-G intron -    22484847
chr3:182846605(-) A-G intron -    22484847
chr3:182846609(-) A-G intron -    22484847
chr3:182846820(-) T-C intron -    22484847
chr3:182848075(-) A-G intron -    22484847
chr3:182848085(-) A-G intron -    22484847
chr3:182851281(-) A-G intron -    22484847
chr3:182851343(-) A-G intron -    22484847
chr3:182851395(-) A-G intron -    22484847
chr3:182855675(-) A-G intron -    22484847
chr3:182855704(-) A-G intron -    22484847
chr3:182855806(-) A-G intron -    22484847
chr3:182855807(-) A-G intron -    22484847
chr3:182855812(-) A-G intron -    22484847
chr3:182856933(-) A-G intron -    22484847
chr3:182856960(-) A-G intron -    22484847
chr3:182857066(-) A-G intron -    22484847
chr3:182857102(-) A-G intron -    22484847
chr3:182864842(-) A-G intron -    22484847
chr3:182864931(-) A-G intron -    22484847
chr3:182864987(-) A-G intron -    22484847
chr3:182864989(-) A-G intron -    22484847
chr3:182865594(-) A-G intron -    22484847
chr3:182865665(-) A-G intron -    22484847
chr3:182865704(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase LAMP3
chr3:182871523-182871524(-) m6A CDS       27773535//27371828
chr3:182871555-182871556(-) m6A CDS       28052920//27773535//27371828
chr3:182871648-182871649(-) m6A CDS       24209618//24981863//28052920//27773535//27371828
chr3:182871732-182871733(-) m6A CDS       24209618//24981863//28052920//27773535
chr3:182871755-182871756(-) m6A CDS       24209618//24981863//28052920//27773535
chr3:182871789-182871790(-) m6A CDS       24209618//24981863//28052920//27773535
chr3:182871950-182871951(-) m6A CDS       24209618//28052920//27773535
chr3:182871999-182872000(-) m6A CDS       24209618//28052920//27773535
chr3:182872041-182872042(-) m6A CDS       28052920//27773535
chr3:182872078-182872079(-) m6A CDS       28052920//27773535
chr3:182872088-182872089(-) m6A CDS       28052920//27773535
chr3:182872131-182872132(-) m6A CDS       27371828
chr3:182878651-182878652(-) m6A 5'UTR//exon//intron       27371828
chr3:182878711-182878712(-) m6A 5'UTR//exon//intron       27371828

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate LAMP3
Exosome Blood     -

Interaction Network (The top 100 interactions):


Interactor1: hcmv-miR-US25-1-5p
Interactor2: LAMP3

Evidence Support:


Strong-Evidence RISC-IP
Support Database ViRBase

References:


PMID 20585629 Target region 5'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line HEK293 cells Interactor2 expression None
Description Here, we identify cellular transcript targets of one of the most highly expressed HCMV encoded miRNAs, miR-US25-1, using a recently developed biochemical approach called RISC immunoprecipitation. Strikingly, the majority of identified transcripts contained miR-US25-1 target sites within the 5'UTR rather than the 3'UTR.

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