Detail Information

Basic Information:


  VIRBase ID:  

VHID00509755

  Virus:  

Human herpesvirus 5 strain AD169

  Host:  

Homo sapiens

  Confidence Score:  

0.7311

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-US25-1-5p:           RNF19A:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hcmv-miR-US25-1-5p RNF19A
miRBase
Accession/Entrez ID		 MIMAT0001581 25897
Organism Human herpesvirus 5 strain AD169 Homo sapiens
Category miRNA mRNA
Alias - RNF19

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR RNF19A
chr8:101289691(-) A-I      intronic
chr8:101289708(-) A-I      intronic
chr8:101302581(-) A-I      intronic
chr8:101302537(-) A-I      intronic
chr8:101302509(-) A-I      intronic
chr8:101298024(-) A-I      intronic
chr8:101292160(-) A-I      intronic
chr8:101292139(-) A-I      intronic
chr8:101289775(-) A-I      intronic
chr8:101289745(-) A-I      intronic
chr8:101289743(-) A-I      intronic
chr8:101289724(-) A-I      intronic
chr8:101316454(-) A-I      intronic
chr8:101316427(-) A-I      intronic
chr8:101316403(-) A-I      intronic
chr8:101289637(-) A-I      intronic
chr8:101289710(-) A-I      intronic
chr8:101316383(-) A-I      intronic
chr8:101316261(-) A-I      intronic
chr8:101316250(-) A-I      intronic
chr8:101316127(-) A-I      intronic
chr8:101316089(-) A-I      intronic
chr8:101315948(-) A-I      intronic
chr8:101318157(-) A-I      intronic
chr8:101284945(-) A-I      intronic
chr8:101288946(-) A-I      intronic
chr8:101289632(-) A-I      intronic
chr8:101289709(-) A-I      intronic
chr8:101289636(-) A-I      intronic
chr8:101312799(-) A-I      5'UTR
chr8:101312875(-) A-I      5'UTR
chr8:101312759(-) A-I      5'UTR
chr8:101312671(-) A-I      intronic
chr8:101316481(-) A-I      intronic
chr8:101316313(-) A-I      intronic
chr8:101302523(-) A-I      intronic
chr8:101316290(-) A-I      intronic
chr8:101316123(-) A-I      intronic
chr8:101317289(-) A-I      intronic
chr8:101288948(-) A-I      intronic
chr8:101284807(-) A-I      intronic
chr8:101288797(-) A-I      intronic
chr8:101316471(-) A-I      intronic
chr8:101316329(-) A-I      intronic
chr8:101316408(-) A-I      intronic
chr8:101315908(-) A-I      intronic
chr8:101316083(-) A-I      intronic
chr8:101302562(-) A-I      intronic
chr8:101315934(-) A-I      intronic
chr8:101316432(-) A-I      intronic
chr8:101312798(-) A-I      5'UTR
chr8:101312845(-) A-I      5'UTR
chr8:101312765(-) A-I      5'UTR
chr8:101312847(-) A-I      5'UTR
chr8:101316485(-) A-I      intronic
chr8:101308570(-) A-I      intronic
chr8:101316323(-) A-I      intronic
chr8:101302494(-) A-I      intronic
chr8:101316042(-) A-I      intronic
chr8:101316038(-) A-I      intronic
chr8:101316065(-) A-I      intronic
chr8:101316341(-) A-I      intronic
chr8:101316475(-) A-I      intronic
chr8:101289678(-) A-I      intronic
chr8:101308448(-) A-I      intronic
chr8:101316072(-) A-I      intronic
chr8:101317296(-) A-I      intronic
chr8:101288871(-) A-I      intronic
chr8:101316463(-) A-I      intronic
chr8:101316276(-) A-I      intronic
chr8:101315907(-) A-I      intronic
chr8:101316263(-) A-I      intronic
chr8:101316345(-) A-I      intronic
chr8:101315969(-) A-I      intronic
chr8:101315895(-) A-I      intronic
chr8:101316078(-) A-I      intronic
chr8:101316296(-) A-I      intronic
chr8:101286240(-) A-I      intronic
chr8:101315947(-) A-I      intronic
chr8:101312702(-) A-I      intronic
chr8:101302468(-) A-I      intronic
chr8:101316300(-) A-I      intronic
chr8:101315954(-) A-I      intronic
chr8:101286816(-) A-I      intronic
chr8:101288859(-) A-I      intronic
chr8:101315960(-) A-I      intronic
chr8:101301115(-) A-I      intronic
chr8:101316431(-) A-I      intronic
chr8:101288927(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED RNF19A
chr8:101271291(-) A-I exon CDS    22327324
chr8:101315917(-) A-I intron -    22327324
chr8:101315934(-) A-I intron -    22327324
chr8:101315947(-) A-I intron -    22327324
chr8:101315954(-) A-I intron -    22327324
chr8:101316281(-) A-I intron -    22327324
chr8:101316300(-) A-I intron -    22327324
chr8:101316323(-) A-I intron -    22327324
chr8:101316341(-) A-I intron -    22327324
chr8:101316475(-) A-I intron -    22327324
chr8:101280019(-) A-G intron -    22484847
chr8:101284807(-) A-G intron -    22484847
chr8:101286172(-) T-C intron -    22484847
chr8:101288797(-) A-G intron -    22484847
chr8:101288861(-) A-G intron -    22484847
chr8:101288903(-) A-G intron -    22484847
chr8:101288927(-) A-G intron -    22484847
chr8:101288948(-) A-G intron -    22484847
chr8:101289678(-) A-G intron -    22484847
chr8:101289792(-) T-C intron -    22484847
chr8:101301115(-) A-G intron -    22484847
chr8:101308585(-) A-T intron -    22484847
chr8:101308593(-) G-T intron -    22484847
chr8:101312765(-) A-G exon 5'UTR    22484847
chr8:101312845(-) A-G exon 5'UTR    22484847
chr8:101312847(-) A-G exon 5'UTR    22484847
chr8:101315907(-) A-G intron -    22484847
chr8:101315908(-) A-G intron -    22484847
chr8:101315917(-) A-G intron -    22484847
chr8:101315934(-) A-G intron -    22484847
chr8:101315947(-) A-G intron -    22484847
chr8:101315954(-) A-G intron -    22484847
chr8:101316042(-) A-G intron -    22484847
chr8:101316044(-) A-G intron -    22484847
chr8:101316081(-) A-G intron -    22484847
chr8:101316118(-) A-G intron -    22484847
chr8:101316281(-) A-G intron -    22484847
chr8:101316290(-) A-G intron -    22484847
chr8:101316293(-) A-G intron -    22484847
chr8:101316296(-) A-G intron -    22484847
chr8:101316300(-) A-G intron -    22484847
chr8:101316306(-) A-G intron -    22484847
chr8:101316323(-) A-G intron -    22484847
chr8:101316329(-) A-G intron -    22484847
chr8:101316341(-) A-G intron -    22484847
chr8:101316345(-) A-G intron -    22484847
chr8:101316431(-) A-G intron -    22484847
chr8:101316432(-) A-G intron -    22484847
chr8:101316441(-) A-G intron -    22484847
chr8:101316457(-) A-G intron -    22484847
chr8:101316463(-) A-G intron -    22484847
chr8:101316475(-) A-G intron -    22484847
chr8:101316481(-) A-G intron -    22484847
chr8:101317233(-) T-C intron -    22484847
chr8:101317296(-) A-G intron -    22484847
chr8:101317358(-) A-C intron -    22484847
chr8:101311310(-) A-G intron -    22484847
chr8:101312372(-) A-G intron -    22484847
chr8:101312382(-) A-G intron -    22484847
chr8:101312385(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase RNF19A
chr8:101269665-101269666(-) m6A 3'UTR       26404942
chr8:101269729-101269730(-) m6A 3'UTR       26404942
chr8:101269821-101269822(-) m6A 3'UTR       26404942
chr8:101269867-101269868(-) m6A 3'UTR       26404942
chr8:101270070-101270071(-) m6A 3'UTR       26404942
chr8:101270219-101270220(-) m6A 3'UTR       26404942
chr8:101270357-101270358(-) m6A 3'UTR       26404942
chr8:101270383-101270384(-) m6A 3'UTR       26404942
chr8:101270426-101270427(-) m6A 3'UTR       26404942
chr8:101270522-101270523(-) m6A 3'UTR       26404942
chr8:101270607-101270608(-) m6A 3'UTR       24284625//26404942//27773535//22608085
chr8:101270726-101270727(-) m6A 3'UTR       24284625//24209618//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr8:101270794-101270795(-) m6A CDS       24284625//24209618//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr8:101270821-101270822(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr8:101270845-101270846(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr8:101270885-101270886(-) m6A CDS       24284625//24209618//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr8:101270906-101270907(-) m6A CDS       24284625//24209618//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr8:101270953-101270954(-) m6A CDS       24284625//24209618//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr8:101271079-101271080(-) m6A CDS       24284625//24209618//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr8:101271189-101271190(-) m6A CDS//exon       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr8:101271203-101271204(-) m6A CDS//exon       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr8:101271225-101271226(-) m6A CDS//exon       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr8:101271269-101271270(-) m6A CDS//exon       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr8:101272084-101272085(-) m6A CDS//exon       24209618//26404942//27773535
chr8:101272151-101272152(-) m6A CDS//exon       27773535//22575960
chr8:101273781-101273782(-) m6A CDS//exon//intron       26404942
chr8:101273862-101273863(-) m6A CDS//exon//intron       26404942//27773535
chr8:101273957-101273958(-) m6A CDS//exon//intron       26404942//27773535
chr8:101276276-101276277(-) m6A CDS//exon//intron       26404942
chr8:101287228-101287229(-) m6A CDS//exon       26404942
chr8:101287276-101287277(-) m6A CDS       26404942
chr8:101287298-101287299(-) m6A CDS       24209618//26404942//27773535
chr8:101287321-101287322(-) m6A CDS       24209618//26404942//27773535
chr8:101299734-101299735(-) m6A CDS       24284625//24209618//24981863//26404942//27773535//22608085
chr8:101299977-101299978(-) m6A CDS       24284625//24209618//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr8:101300019-101300020(-) m6A CDS       24284625//24209618//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr8:101300030-101300031(-) m6A CDS       24284625//24209618//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr8:101300085-101300086(-) m6A CDS       24284625//24209618//24981863//28052920//26404942//27773535//22575960//22608085
chr8:101300310-101300311(-) m6A 5'UTR//CDS       24284625//24981863//26404942//27773535//22608085
chr8:101300346-101300347(-) m6A CDS//intron       24284625//24981863//26404942//27773535//22608085
chr8:101300393-101300394(-) m6A CDS//intron       24981863//26404942//27773535//22608085
chr8:101300438-101300439(-) m6A 5'UTR       24981863//26404942//27773535//22608085
chr8:101300462-101300463(-) m6A 5'UTR       24981863//26404942//27773535//22608085
chr8:101312761-101312762(-) m6A 5'UTR//intron       24981863//26404942//27773535//22608085
chr8:101315389-101315390(-) m6A 5'UTR//exon//intron       26404942
chr8:101315405-101315406(-) m6A 5'UTR//exon//intron       26404942
chr8:101315456-101315457(-) m6A 5'UTR//exon//intron       26404942
chr8:101322190-101322191(-) m6A 5'UTR//exon//intron       24981863//27371828//27773536
chr8:101322247-101322248(-) m6A 5'UTR//exon//intron       25456834//24981863//27371828//27773536
chr8:101322374-101322375(-) m1A 5'UTR//exon//intron       26863196
chr8:101322479-101322480(-) m6A 5'UTR//intron       -
chr8:101324577-101324578(-) m6A 5'UTR//intron       27371828
chr8:101324618-101324619(-) m6A 5'UTR//intron       -
chr8:101348379-101348380(-) m6A 5'UTR//exon//intron       -

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate RNF19A
Chromatin K562 cells     -
Exosome Blood     -
Membrane K562 cells     -
Nucleoplasm K562 cells     -
Nucleus HCC cell line (HepG2)|HeLa-S3 cells     -
Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):


Interactor1: hcmv-miR-US25-1-5p
Interactor2: RNF19A

Evidence Support:


Strong-Evidence RISC-IP
Support Database ViRBase

References:


PMID 20585629 Target region 5'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line HEK293 cells Interactor2 expression None
Description Here, we identify cellular transcript targets of one of the most highly expressed HCMV encoded miRNAs, miR-US25-1, using a recently developed biochemical approach called RISC immunoprecipitation. Strikingly, the majority of identified transcripts contained miR-US25-1 target sites within the 5'UTR rather than the 3'UTR.

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