Basic Information:

  VIRBase ID:  

VHID00509077

  Virus:  

Human herpesvirus 5 strain AD169

  Host:  

Homo sapiens

  Confidence Score:  

0.7311

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-US25-1-5p:  MIMAT0001581          FOXJ3:  NM_001198851     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hcmv-miR-US25-1-5p	FOXJ3
miRBase Accession/Entrez ID	MIMAT0001581	22887
Organism	Human herpesvirus 5 strain AD169	Homo sapiens
Category	miRNA	mRNA
Alias	-	-

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	FOXJ3	chr1:42793814(-) A-I      intronic chr1:42794554(-) A-I      intronic chr1:42794503(-) A-I      intronic chr1:42793942(-) A-I      intronic chr1:42794476(-) A-I      intronic chr1:42794551(-) A-I      intronic chr1:42796970(-) A-I      intronic chr1:42677096(-) A-I      intronic chr1:42796958(-) A-I      intronic chr1:42767038(-) A-I      intronic chr1:42692071(-) A-I      intronic chr1:42648433(-) A-I      intronic chr1:42648703(-) A-I      intronic chr1:42662983(-) A-I      intronic chr1:42765470(-) A-I      intronic chr1:42796241(-) A-I      intronic chr1:42662993(-) A-I      intronic chr1:42753631(-) A-I      intronic chr1:42753434(-) A-I      intronic chr1:42767138(-) A-I      intronic chr1:42648789(-) A-I      intronic chr1:42648254(-) A-I      intronic chr1:42648183(-) A-I      intronic chr1:42648812(-) A-I      intronic chr1:42652527(-) A-I      intronic chr1:42662286(-) A-I      intronic chr1:42752924(-) A-I      intronic chr1:42672747(-) A-I      intronic chr1:42662288(-) A-I      intronic chr1:42702790(-) A-I      intronic chr1:42702853(-) A-I      intronic chr1:42796201(-) A-I      intronic chr1:42796197(-) A-I      intronic chr1:42796058(-) A-I      intronic chr1:42794537(-) A-I      intronic chr1:42794444(-) A-I      intronic chr1:42794389(-) A-I      intronic chr1:42793827(-) A-I      intronic chr1:42765496(-) A-I      intronic chr1:42793794(-) A-I      intronic chr1:42793771(-) A-I      intronic chr1:42784289(-) A-I      intronic chr1:42784232(-) A-I      intronic chr1:42784219(-) A-I      intronic chr1:42784217(-) A-I      intronic chr1:42784110(-) A-I      intronic chr1:42778789(-) A-I      intronic chr1:42778024(-) A-I      intronic chr1:42777975(-) A-I      intronic chr1:42648204(-) A-I      intronic chr1:42767086(-) A-I      intronic chr1:42767076(-) A-I      intronic chr1:42752911(-) A-I      intronic chr1:42752899(-) A-I      intronic chr1:42702963(-) A-I      intronic chr1:42728293(-) A-I      intronic chr1:42737412(-) A-I      intronic chr1:42752415(-) A-I      intronic chr1:42752442(-) A-I      intronic chr1:42752478(-) A-I      intronic chr1:42767066(-) A-I      intronic chr1:42767060(-) A-I      intronic chr1:42767031(-) A-I      intronic chr1:42766391(-) A-I      intronic chr1:42765788(-) A-I      intronic chr1:42765752(-) A-I      intronic chr1:42648372(-) A-I      intronic chr1:42648363(-) A-I      intronic chr1:42648357(-) A-I      intronic chr1:42648348(-) A-I      intronic chr1:42648347(-) A-I      intronic chr1:42648306(-) A-I      intronic chr1:42648382(-) A-I      intronic chr1:42648401(-) A-I      intronic chr1:42648417(-) A-I      intronic chr1:42648702(-) A-I      intronic chr1:42766253(-) A-I      intronic chr1:42752889(-) A-I      intronic chr1:42766254(-) A-I      intronic chr1:42791653(-) A-I      intronic chr1:42702086(-) A-I      intronic chr1:42648729(-) A-I      intronic chr1:42794434(-) A-I      intronic chr1:42796064(-) A-I      intronic chr1:42766274(-) A-I      intronic chr1:42793695(-) A-I      intronic chr1:42761328(-) A-I      intronic chr1:42666383(-) A-I      intronic chr1:42766275(-) A-I      intronic chr1:42648320(-) A-I      intronic chr1:42784667(-) A-I      intronic chr1:42775955(-) A-I      intronic chr1:42767004(-) A-I      intronic chr1:42796138(-) A-I      intronic chr1:42648799(-) A-I      intronic chr1:42648835(-) A-I      intronic chr1:42701451(-) A-I      intronic chr1:42752902(-) A-I      intronic chr1:42752844(-) A-I      intronic chr1:42663554(-) A-I      intronic chr1:42766372(-) A-I      intronic chr1:42794609(-) A-I      intronic chr1:42648396(-) A-I      intronic chr1:42702902(-) A-I      intronic chr1:42648803(-) A-I      intronic chr1:42796240(-) A-I      intronic chr1:42728372(-) A-I      intronic chr1:42765357(-) A-I      intronic chr1:42766229(-) A-I      intronic chr1:42648783(-) A-I      intronic chr1:42701960(-) A-I      intronic chr1:42672630(-) A-I      intronic chr1:42752949(-) A-I      intronic chr1:42648362(-) A-I      intronic chr1:42704441(-) A-I      intronic chr1:42794539(-) A-I      intronic chr1:42778840(-) A-I      intronic chr1:42710065(-) A-I      intronic chr1:42648251(-) A-I      intronic chr1:42648226(-) A-I      intronic chr1:42784645(-) A-I      intronic chr1:42648351(-) A-I      intronic chr1:42766982(-) A-I      intronic chr1:42794449(-) A-I      intronic chr1:42778008(-) A-I      intronic chr1:42793946(-) A-I      intronic chr1:42648216(-) A-I      intronic chr1:42784124(-) A-I      intronic chr1:42766281(-) A-I      intronic chr1:42784080(-) A-I      intronic chr1:42737528(-) A-I      intronic chr1:42672551(-) A-I      intronic chr1:42702002(-) A-I      intronic chr1:42775890(-) A-I      intronic chr1:42794533(-) A-I      intronic chr1:42648864(-) A-I      intronic chr1:42737419(-) A-I      intronic chr1:42781869(-) A-I      intronic chr1:42793884(-) A-I      intronic chr1:42784844(-) A-I      intronic chr1:42794508(-) A-I      intronic chr1:42648851(-) A-I      intronic chr1:42710063(-) A-I      intronic chr1:42752989(-) A-I      intronic chr1:42753010(-) A-I      intronic chr1:42752381(-) A-I      intronic chr1:42793858(-) A-I      intronic chr1:42784806(-) A-I      intronic chr1:42794619(-) A-I      intronic chr1:42778740(-) A-I      intronic chr1:42692026(-) A-I      intronic chr1:42648807(-) A-I      intronic chr1:42784779(-) A-I      intronic chr1:42766366(-) A-I      intronic chr1:42793702(-) A-I      intronic chr1:42793885(-) A-I      intronic chr1:42767140(-) A-I      intronic chr1:42742608(-) A-I      intronic chr1:42794502(-) A-I      intronic chr1:42648901(-) A-I      intronic chr1:42648234(-) A-I      intronic chr1:42648441(-) A-I      intronic chr1:42793804(-) A-I      intronic chr1:42761321(-) A-I      intronic chr1:42767160(-) A-I      intronic chr1:42648415(-) A-I      intronic chr1:42793803(-) A-I      intronic chr1:42766235(-) A-I      intronic chr1:42648442(-) A-I      intronic chr1:42648689(-) A-I      intronic chr1:42752767(-) A-I      intronic chr1:42766445(-) A-I      intronic chr1:42794380(-) A-I      intronic chr1:42703868(-) A-I      intronic chr1:42790186(-) A-I      intronic chr1:42793723(-) A-I      intronic chr1:42703801(-) A-I      intronic chr1:42752929(-) A-I      intronic chr1:42794610(-) A-I      intronic chr1:42793961(-) A-I      intronic chr1:42794494(-) A-I      intronic chr1:42701427(-) A-I      intronic chr1:42796143(-) A-I      intronic chr1:42648754(-) A-I      intronic chr1:42648883(-) A-I      intronic chr1:42782114(-) A-I      intronic chr1:42781874(-) A-I      intronic chr1:42778749(-) A-I      intronic chr1:42766340(-) A-I      intronic chr1:42741230(-) A-I      intronic chr1:42793964(-) A-I      intronic chr1:42672965(-) A-I      intronic chr1:42648687(-) A-I      intronic chr1:42784109(-) A-I      intronic chr1:42702774(-) A-I      intronic chr1:42742627(-) A-I      intronic chr1:42796105(-) A-I      intronic chr1:42701442(-) A-I      intronic chr1:42778886(-) A-I      intronic chr1:42714012(-) A-I      intronic chr1:42701646(-) A-I      intronic chr1:42648701(-) A-I      intronic chr1:42648342(-) A-I      intronic chr1:42702879(-) A-I      intronic chr1:42793906(-) A-I      intronic chr1:42793966(-) A-I      intronic chr1:42766327(-) A-I      intronic chr1:42648908(-) A-I      intronic chr1:42778018(-) A-I      intronic chr1:42767111(-) A-I      intronic chr1:42793861(-) A-I      intronic chr1:42714503(-) A-I      intronic chr1:42648774(-) A-I      intronic chr1:42752469(-) A-I      intronic chr1:42761368(-) A-I      intronic chr1:42648825(-) A-I      intronic chr1:42784757(-) A-I      intronic chr1:42701438(-) A-I      intronic chr1:42648241(-) A-I      intronic chr1:42793795(-) A-I      intronic chr1:42752433(-) A-I      intronic chr1:42752484(-) A-I      intronic chr1:42703922(-) A-I      intronic chr1:42758736(-) A-I      intronic chr1:42780060(-) A-I      intronic chr1:42672681(-) A-I      intronic chr1:42780165(-) A-I      intronic chr1:42648780(-) A-I      intronic chr1:42701269(-) A-I      intronic chr1:42780059(-) A-I      intronic chr1:42794453(-) A-I      intronic chr1:42755747(-) A-I      intronic chr1:42793845(-) A-I      intronic chr1:42756477(-) A-I      intronic chr1:42778002(-) A-I      intronic chr1:42796214(-) A-I      intronic chr1:42793905(-) A-I      intronic chr1:42755746(-) A-I      intronic chr1:42784867(-) A-I      intronic chr1:42756480(-) A-I      intronic chr1:42663588(-) A-I      intronic chr1:42784145(-) A-I      intronic chr1:42648364(-) A-I      intronic chr1:42776215(-) A-I      intronic chr1:42755801(-) A-I      intronic chr1:42672612(-) A-I      intronic chr1:42776256(-) A-I      intronic chr1:42648886(-) A-I      intronic chr1:42703972(-) A-I      intronic chr1:42784150(-) A-I      intronic chr1:42703738(-) A-I      intronic chr1:42778010(-) A-I      intronic chr1:42752782(-) A-I      intronic chr1:42672586(-) A-I      intronic chr1:42648261(-) A-I      intronic chr1:42702857(-) A-I      intronic chr1:42793724(-) A-I      intronic chr1:42648880(-) A-I      intronic chr1:42648329(-) A-I      intronic chr1:42752997(-) A-I      intronic chr1:42760238(-) A-I      intronic chr1:42704282(-) A-I      intronic chr1:42669501(-) A-I      intronic chr1:42766435(-) A-I      intronic chr1:42784288(-) A-I      intronic chr1:42651136(-) A-I      intronic chr1:42703844(-) A-I      intronic chr1:42772152(-) A-I      intronic chr1:42648870(-) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	FOXJ3	chr1:42702109(-) A-I intron -    21960545 chr1:42766340(-) A-I intron -    21960545 chr1:42648226(-) A-G intron -    22484847 chr1:42648251(-) A-G intron -    22484847 chr1:42648261(-) A-G intron -    22484847 chr1:42648351(-) A-G intron -    22484847 chr1:42648362(-) A-G intron -    22484847 chr1:42648364(-) A-G intron -    22484847 chr1:42648415(-) A-G intron -    22484847 chr1:42648701(-) A-G intron -    22484847 chr1:42648729(-) A-G intron -    22484847 chr1:42648774(-) A-G intron -    22484847 chr1:42648780(-) A-G intron -    22484847 chr1:42648783(-) A-G intron -    22484847 chr1:42648803(-) A-G intron -    22484847 chr1:42648807(-) A-G intron -    22484847 chr1:42648851(-) A-G intron -    22484847 chr1:42648883(-) A-G intron -    22484847 chr1:42648886(-) A-G intron -    22484847 chr1:42648908(-) A-G intron -    22484847 chr1:42669501(-) A-G intron -    22484847 chr1:42702002(-) A-G intron -    22484847 chr1:42702086(-) A-G intron -    22484847 chr1:42702774(-) A-G intron -    22484847 chr1:42702857(-) A-G intron -    22484847 chr1:42702879(-) A-G intron -    22484847 chr1:42702902(-) A-G intron -    22484847 chr1:42703801(-) A-G intron -    22484847 chr1:42703844(-) A-G intron -    22484847 chr1:42703868(-) A-G intron -    22484847 chr1:42703972(-) A-G intron -    22484847 chr1:42721592(-) G-A intron -    22484847 chr1:42742608(-) A-G intron -    22484847 chr1:42752469(-) A-G intron -    22484847 chr1:42752484(-) A-G intron -    22484847 chr1:42752767(-) A-G intron -    22484847 chr1:42752782(-) A-G intron -    22484847 chr1:42752844(-) A-G intron -    22484847 chr1:42752889(-) A-G intron -    22484847 chr1:42752902(-) A-G intron -    22484847 chr1:42752929(-) A-G intron -    22484847 chr1:42752949(-) A-G intron -    22484847 chr1:42752989(-) A-G intron -    22484847 chr1:42752997(-) A-G intron -    22484847 chr1:42753010(-) A-G intron -    22484847 chr1:42758538(-) T-C intron -    22484847 chr1:42760238(-) A-G intron -    22484847 chr1:42760448(-) T-C intron -    22484847 chr1:42765357(-) A-G intron -    22484847 chr1:42766229(-) A-G intron -    22484847 chr1:42766235(-) A-G intron -    22484847 chr1:42766253(-) A-G intron -    22484847 chr1:42766254(-) A-G intron -    22484847 chr1:42766274(-) A-G intron -    22484847 chr1:42766275(-) A-G intron -    22484847 chr1:42766327(-) A-G intron -    22484847 chr1:42766340(-) A-G intron -    22484847 chr1:42766366(-) A-G intron -    22484847 chr1:42766372(-) A-G intron -    22484847 chr1:42766435(-) A-G intron -    22484847 chr1:42778008(-) A-G intron -    22484847 chr1:42784124(-) A-G intron -    22484847 chr1:42784145(-) A-G intron -    22484847 chr1:42784150(-) A-G intron -    22484847 chr1:42784288(-) A-G intron -    22484847 chr1:42784779(-) A-G intron -    22484847 chr1:42784844(-) A-G intron -    22484847 chr1:42793845(-) A-G intron -    22484847 chr1:42794434(-) A-G intron -    22484847 chr1:42794494(-) A-G intron -    22484847 chr1:42794508(-) A-G intron -    22484847 chr1:42794610(-) A-G intron -    22484847 chr1:42796064(-) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	FOXJ3	chr1:42642672-42642673(-) m6A 3'UTR       27773535 chr1:42642682-42642683(-) m6A 3'UTR       27773535 chr1:42642715-42642716(-) m6A 3'UTR       27773535 chr1:42642748-42642749(-) m6A 3'UTR       27773535 chr1:42642817-42642818(-) m6A 3'UTR       27773535 chr1:42645083-42645084(-) m6A 3'UTR       24284625//24209618//27773535 chr1:42645248-42645249(-) m6A 3'UTR       24284625//24209618//24981863//27773535//27371828//22608085 chr1:42645292-42645293(-) m6A 3'UTR       24981863 chr1:42645296-42645297(-) m6A 3'UTR       24284625//24209618//24981863//27773535//27371828//22608085 chr1:42645356-42645357(-) m6A 3'UTR       24284625//24209618//24981863//27773535//27371828//22608085 chr1:42645363-42645364(-) m6A 3'UTR       24284625//24209618//24981863//28052920//27773535//27371828//22608085 chr1:42645477-42645478(-) m6A CDS       24209618//27773535//27371828 chr1:42647599-42647600(-) m6A CDS       24209618//27773535 chr1:42654410-42654411(-) m6A CDS       27773535 chr1:42654429-42654430(-) m6A CDS       27773535 chr1:42657038-42657039(-) m6A CDS       24284625//24981863//27773535//27371828 chr1:42657380-42657381(-) m6A CDS       24981863//27773535 chr1:42660658-42660659(-) m6A CDS       24981863//27773535 chr1:42664803-42664804(-) m6A CDS       27773535 chr1:42664830-42664831(-) m6A CDS       27773535 chr1:42671641-42671642(-) m6A 5'UTR//intron       27773535 chr1:42693617-42693618(-) m6A CDS       27773535 chr1:42730626-42730627(-) m6A 3'UTR//intron       27773535 chr1:42730695-42730696(-) m6A 3'UTR//intron       27773535 chr1:42730719-42730720(-) m6A 3'UTR//intron       27773535 chr1:42730831-42730832(-) m6A CDS       22608085 chr1:42744153-42744154(-) m6A CDS       24284625//24981863//26404942//27773535//22608085 chr1:42744187-42744188(-) m6A CDS       24284625//24981863//27773535//22608085 chr1:42744236-42744237(-) m6A CDS       24284625//24981863//27773535//22575960//22608085 chr1:42744304-42744305(-) m6A CDS       24284625//24981863//27773535//22575960//22608085 chr1:42744330-42744331(-) m6A CDS       24981863//27773535//22575960//22608085 chr1:42776749-42776750(-) m6A CDS       27773535//22575960//22608085 chr1:42800803-42800804(-) m6A 5'UTR//intron       24981863 chr1:42801109-42801110(-) m6A intron       25456834//22608085 chr1:42801126-42801127(-) m6A intron       25456834//22608085 chr1:42801430-42801431(-) m6A 5'UTR       25456834//24981863 chr1:42801450-42801451(-) m6A 5'UTR       25456834//24981863 chr1:42801476-42801477(-) m6A 5'UTR       25456834//24981863

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	FOXJ3	Chromatin K562 cells     - Cytoplasm Nasopharyngeal carcinoma cells     20498841 Cytosol HCC cell line (HepG2)     - Exosome Blood     - Membrane HCC cell line (HepG2)|K562 cells     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus Nasopharyngeal carcinoma cells     20498841 Nucleus HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     -

Interaction Network (The top 100 interactions):

Interactor1: hcmv-miR-US25-1-5p
Interactor2: FOXJ3

Evidence Support:

Strong-Evidence	RISC-IP
Support Database	ViRBase

References:

PMID	20585629	Target region	5'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	HEK293 cells	Interactor2 expression	None
Description	Here, we identify cellular transcript targets of one of the most highly expressed HCMV encoded miRNAs, miR-US25-1, using a recently developed biochemical approach called RISC immunoprecipitation. Strikingly, the majority of identified transcripts contained miR-US25-1 target sites within the 5'UTR rather than the 3'UTR.