Detail Information

Basic Information:


  VIRBase ID:  

VHID00509038

  Virus:  

Human herpesvirus 5 strain AD169

  Host:  

Homo sapiens

  Confidence Score:  

0.7311

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-US25-1-5p:           RAB11FIP2:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hcmv-miR-US25-1-5p RAB11FIP2
miRBase
Accession/Entrez ID		 MIMAT0001581 22841
Organism Human herpesvirus 5 strain AD169 Homo sapiens
Category miRNA mRNA
Alias - nRip11//Rab11-FIP2

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR RAB11FIP2
chr10:119776622(-) A-I      intronic
chr10:119776638(-) A-I      intronic

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase RAB11FIP2
chr10:119765259-119765260(-) m6A 3'UTR       24981863
chr10:119765266-119765267(-) m6A 3'UTR//exon       24981863
chr10:119765376-119765377(-) m6A 3'UTR//intron       24981863//27773535
chr10:119765396-119765397(-) m6A 3'UTR//intron       27773535
chr10:119765407-119765408(-) m6A 3'UTR//intron       27773535
chr10:119767400-119767401(-) m6A 3'UTR//intron       24981863
chr10:119767411-119767412(-) m6A 3'UTR//intron       24981863
chr10:119768259-119768260(-) m6A 3'UTR//intron       27773535
chr10:119768351-119768352(-) m6A 3'UTR//intron       24981863//27773535//22608085
chr10:119768424-119768425(-) m6A 3'UTR//intron       24284625//24981863//27773535//22608085
chr10:119768441-119768442(-) m6A 3'UTR//intron       24284625//24209618//24981863//27773535//22608085
chr10:119768477-119768478(-) m6A 3'UTR//intron       24284625//24209618//24981863//27773535//27371828//22608085
chr10:119768544-119768545(-) m6A CDS//intron       24284625//24209618//24981863//27773535//27371828//22575960//22608085
chr10:119768611-119768612(-) m6A CDS//exon       24284625//24209618//24981863//27773535//27371828//22575960//22608085
chr10:119768619-119768620(-) m6A CDS//exon       24284625//24209618//24981863//27773535//27371828//22575960//22608085
chr10:119768635-119768636(-) m6A CDS//exon       24284625//24209618//24981863//27773535//27371828//22575960//22608085
chr10:119768652-119768653(-) m6A CDS//exon       24284625//24209618//24981863//27773535//27371828//22575960//22608085
chr10:119768661-119768662(-) m6A CDS//exon       24284625//24209618//24981863//27773535//27371828//22575960//22608085
chr10:119774591-119774592(-) m6A CDS//exon       24284625//24981863//27773535//22608085
chr10:119798554-119798555(-) m6A CDS//exon       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr10:119798625-119798626(-) m6A CDS//exon       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr10:119798724-119798725(-) m6A CDS//exon       24284625//24209618//24981863//27773535//27371828//22575960//22608085
chr10:119798749-119798750(-) m6A CDS//exon       24284625//24209618//24981863//27773535//27371828//22575960//22608085
chr10:119798756-119798757(-) m6A CDS//exon       24284625//24209618//24981863//27773535//27371828//22575960//22608085
chr10:119798850-119798851(-) m6A CDS//exon       24284625//24209618//24981863//27773535//27371828//22608085
chr10:119798896-119798897(-) m6A CDS//exon       24284625//24209618//24981863//27773535//27371828//22608085
chr10:119798924-119798925(-) m6A CDS//exon       24284625//24209618//24981863//27773535//22608085
chr10:119799648-119799649(-) m6A CDS//exon       24284625//24981863//27773535//22608085
chr10:119799670-119799671(-) m6A CDS//exon       24284625//24981863//27773535//22608085
chr10:119799684-119799685(-) m6A CDS//exon       24284625//24981863//27773535//22608085
chr10:119799709-119799710(-) m6A CDS//exon       24284625//24981863//27773535//22608085
chr10:119799799-119799800(-) m6A CDS//exon       24284625//24981863//27773535//22608085
chr10:119799894-119799895(-) m6A CDS       24284625//24209618//24981863//26404942//27773535//22575960//22608085
chr10:119799951-119799952(-) m6A CDS       24284625//24209618//24981863//27773535//22575960//22608085
chr10:119799956-119799957(-) m6A CDS       24284625//24209618//24981863//27773535//22575960//22608085
chr10:119799995-119799996(-) m6A CDS       24284625//24209618//24981863//27773535//22575960//22608085
chr10:119800034-119800035(-) m6A CDS       24284625//24981863//27773535//22575960//22608085
chr10:119800054-119800055(-) m6A CDS       24284625//24981863//27773535//22575960//22608085
chr10:119805325-119805326(-) m6A CDS       24284625//24981863//27773535//22608085
chr10:119805342-119805343(-) m6A CDS       24981863//27773535//22608085
chr10:119805866-119805867(-) m6A 5'UTR       24284625
chr10:119805947-119805948(-) m6A 5'UTR       27773536

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate RAB11FIP2
Exosome Blood     -
Nucleoplasm K562 cells     -
Nucleus HCC cell line (HepG2)|K562 cells     -

Interaction Network (The top 100 interactions):


Interactor1: hcmv-miR-US25-1-5p
Interactor2: RAB11FIP2

Evidence Support:


Strong-Evidence RISC-IP
Support Database ViRBase

References:


PMID 20585629 Target region 5'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line HEK293 cells Interactor2 expression None
Description Here, we identify cellular transcript targets of one of the most highly expressed HCMV encoded miRNAs, miR-US25-1, using a recently developed biochemical approach called RISC immunoprecipitation. Strikingly, the majority of identified transcripts contained miR-US25-1 target sites within the 5'UTR rather than the 3'UTR.

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