Detail Information

Basic Information:


  VIRBase ID:  

VHID00508732

  Virus:  

Human herpesvirus 5 strain AD169

  Host:  

Homo sapiens

  Confidence Score:  

0.7311

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-US25-1-5p:           TMED10:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hcmv-miR-US25-1-5p TMED10
miRBase
Accession/Entrez ID		 MIMAT0001581 10972
Organism Human herpesvirus 5 strain AD169 Homo sapiens
Category miRNA mRNA
Alias - p23//P24(DELTA)//p24d1//S31I125//S31III125//Tmp-21-I//TMP21

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR TMED10
chr14:75604507(-) A-I      intronic
chr14:75604479(-) A-I      intronic
chr14:75604463(-) A-I      intronic
chr14:75604449(-) A-I      intronic
chr14:75604448(-) A-I      intronic
chr14:75616614(-) A-I      intronic
chr14:75599058(-) A-I      3'UTR
chr14:75599052(-) A-I      3'UTR
chr14:75599047(-) A-I      3'UTR
chr14:75599039(-) A-I      3'UTR
chr14:75599028(-) A-I      3'UTR
chr14:75599009(-) A-I      3'UTR
chr14:75599008(-) A-I      3'UTR
chr14:75599005(-) A-I      3'UTR
chr14:75604478(-) A-I      intronic
chr14:75604471(-) A-I      intronic
chr14:75604473(-) A-I      intronic
chr14:75616590(-) A-I      intronic
chr14:75616582(-) A-I      intronic
chr14:75611549(-) A-I      intronic
chr14:75630878(-) A-I      intronic
chr14:75630866(-) A-I      intronic
chr14:75630865(-) A-I      intronic
chr14:75630832(-) A-I      intronic
chr14:75611575(-) A-I      intronic
chr14:75616624(-) A-I      intronic
chr14:75616640(-) A-I      intronic
chr14:75616684(-) A-I      intronic
chr14:75611529(-) A-I      intronic
chr14:75604446(-) A-I      intronic
chr14:75630874(-) A-I      intronic
chr14:75609700(-) A-I      intronic
chr14:75609740(-) A-I      intronic
chr14:75609741(-) A-I      intronic
chr14:75609744(-) A-I      intronic
chr14:75609766(-) A-I      intronic
chr14:75609781(-) A-I      intronic
chr14:75609819(-) A-I      intronic
chr14:75610420(-) A-I      intronic
chr14:75610450(-) A-I      intronic
chr14:75610457(-) A-I      intronic
chr14:75610493(-) A-I      intronic
chr14:75610574(-) A-I      intronic
chr14:75611492(-) A-I      intronic
chr14:75611493(-) A-I      intronic
chr14:75611517(-) A-I      intronic
chr14:75611525(-) A-I      intronic
chr14:75611554(-) A-I      intronic
chr14:75612269(-) A-I      intronic
chr14:75612297(-) A-I      intronic
chr14:75612309(-) A-I      intronic
chr14:75612323(-) A-I      intronic
chr14:75612326(-) A-I      intronic
chr14:75612341(-) A-I      intronic
chr14:75612346(-) A-I      intronic
chr14:75612362(-) A-I      intronic
chr14:75612366(-) A-I      intronic
chr14:75612368(-) A-I      intronic
chr14:75612378(-) A-I      intronic
chr14:75612427(-) A-I      intronic
chr14:75613927(-) A-I      intronic
chr14:75614064(-) A-I      intronic
chr14:75614124(-) A-I      intronic
chr14:75615734(-) A-I      intronic
chr14:75615909(-) A-I      intronic
chr14:75616643(-) A-I      intronic
chr14:75616694(-) A-I      intronic
chr14:75618047(-) A-I      intronic
chr14:75618194(-) A-I      intronic
chr14:75619885(-) A-I      intronic
chr14:75620981(-) A-I      intronic
chr14:75621022(-) A-I      intronic
chr14:75621061(-) A-I      intronic
chr14:75621764(-) A-I      intronic
chr14:75621841(-) A-I      intronic
chr14:75621850(-) A-I      intronic
chr14:75621865(-) A-I      intronic
chr14:75623419(-) A-I      intronic
chr14:75623423(-) A-I      intronic
chr14:75625169(-) A-I      intronic
chr14:75625195(-) A-I      intronic
chr14:75625204(-) A-I      intronic
chr14:75625263(-) A-I      intronic
chr14:75625411(-) A-I      intronic
chr14:75625440(-) A-I      intronic
chr14:75625445(-) A-I      intronic
chr14:75625465(-) A-I      intronic
chr14:75625503(-) A-I      intronic
chr14:75625515(-) A-I      intronic
chr14:75625518(-) A-I      intronic
chr14:75625588(-) A-I      intronic
chr14:75625624(-) A-I      intronic
chr14:75627591(-) A-I      intronic
chr14:75628885(-) A-I      intronic
chr14:75628886(-) A-I      intronic
chr14:75628930(-) A-I      intronic
chr14:75629735(-) A-I      intronic
chr14:75629939(-) A-I      intronic
chr14:75629943(-) A-I      intronic
chr14:75630063(-) A-I      intronic
chr14:75630099(-) A-I      intronic
chr14:75630799(-) A-I      intronic
chr14:75630877(-) A-I      intronic
chr14:75636712(-) A-I      intronic
chr14:75636808(-) A-I      intronic
chr14:75636818(-) A-I      intronic
chr14:75639966(-) A-I      intronic
chr14:75639968(-) A-I      intronic
chr14:75641627(-) A-I      intronic
chr14:75615790(-) A-I      intronic
chr14:75609584(-) A-I      intronic
chr14:75606303(-) A-I      intronic
chr14:75639013(-) A-I      intronic
chr14:75603761(-) A-I      intronic
chr14:75616724(-) A-I      intronic
chr14:75607518(-) A-I      intronic
chr14:75604579(-) A-I      intronic
chr14:75607248(-) A-I      intronic
chr14:75640531(-) A-I      intronic
chr14:75620556(-) A-I      intronic
chr14:75615895(-) A-I      intronic
chr14:75640616(-) A-I      intronic
chr14:75625107(-) A-I      intronic
chr14:75611634(-) A-I      intronic
chr14:75617743(-) A-I      intronic
chr14:75604550(-) A-I      intronic
chr14:75607418(-) A-I      intronic
chr14:75607245(-) A-I      intronic
chr14:75641696(-) A-I      intronic
chr14:75612232(-) A-I      intronic
chr14:75607500(-) A-I      intronic
chr14:75604615(-) A-I      intronic
chr14:75610554(-) A-I      intronic
chr14:75615789(-) A-I      intronic
chr14:75636726(-) A-I      intronic
chr14:75619518(-) A-I      intronic
chr14:75631329(-) A-I      intronic
chr14:75603044(-) A-I      intronic
chr14:75613977(-) A-I      intronic
chr14:75604132(-) A-I      intronic
chr14:75623466(-) A-I      intronic
chr14:75611471(-) A-I      intronic
chr14:75639844(-) A-I      intronic
chr14:75606270(-) A-I      intronic
chr14:75606295(-) A-I      intronic
chr14:75606932(-) A-I      intronic
chr14:75606942(-) A-I      intronic
chr14:75607075(-) A-I      intronic
chr14:75607159(-) A-I      intronic
chr14:75607166(-) A-I      intronic
chr14:75607167(-) A-I      intronic
chr14:75607176(-) A-I      intronic
chr14:75607208(-) A-I      intronic
chr14:75607287(-) A-I      intronic
chr14:75607289(-) A-I      intronic
chr14:75607348(-) A-I      intronic
chr14:75607541(-) A-I      intronic
chr14:75609596(-) A-I      intronic
chr14:75619652(-) A-I      intronic
chr14:75611499(-) A-I      intronic
chr14:75621889(-) A-I      intronic
chr14:75620747(-) A-I      intronic
chr14:75607335(-) A-I      intronic
chr14:75640533(-) A-I      intronic
chr14:75606263(-) A-I      intronic
chr14:75604496(-) A-I      intronic
chr14:75620838(-) A-I      intronic
chr14:75615802(-) A-I      intronic
chr14:75625234(-) A-I      intronic
chr14:75603078(-) A-I      intronic
chr14:75612301(-) A-I      intronic
chr14:75620674(-) A-I      intronic
chr14:75606952(-) A-I      intronic
chr14:75632100(-) A-I      intronic
chr14:75625104(-) A-I      intronic
chr14:75638249(-) A-I      intronic
chr14:75614057(-) A-I      intronic
chr14:75625544(-) A-I      intronic
chr14:75613988(-) A-I      intronic
chr14:75603941(-) A-I      intronic
chr14:75612246(-) A-I      intronic
chr14:75630144(-) A-I      intronic
chr14:75620729(-) A-I      intronic
chr14:75639901(-) A-I      intronic
chr14:75604508(-) A-I      intronic
chr14:75606968(-) A-I      intronic
chr14:75615819(-) A-I      intronic
chr14:75606218(-) A-I      intronic
chr14:75616723(-) A-I      intronic
chr14:75611505(-) A-I      intronic
chr14:75603985(-) A-I      intronic
chr14:75614061(-) A-I      intronic
chr14:75610585(-) A-I      intronic
chr14:75611641(-) A-I      intronic
chr14:75616657(-) A-I      intronic
chr14:75630134(-) A-I      intronic
chr14:75639906(-) A-I      intronic
chr14:75616768(-) A-I      intronic
chr14:75603947(-) A-I      intronic
chr14:75606256(-) A-I      intronic
chr14:75639132(-) A-I      intronic
chr14:75602959(-) A-I      intronic
chr14:75611635(-) A-I      intronic
chr14:75602972(-) A-I      intronic
chr14:75607020(-) A-I      intronic
chr14:75609592(-) A-I      intronic
chr14:75629813(-) A-I      intronic
chr14:75624152(-) A-I      intronic
chr14:75636884(-) A-I      intronic
chr14:75611565(-) A-I      intronic
chr14:75625175(-) A-I      intronic
chr14:75616658(-) A-I      intronic
chr14:75611566(-) A-I      intronic
chr14:75603918(-) A-I      intronic
chr14:75640030(-) A-I      intronic
chr14:75623475(-) A-I      intronic
chr14:75639206(-) A-I      intronic
chr14:75639871(-) A-I      intronic
chr14:75604500(-) A-I      intronic
chr14:75625625(-) A-I      intronic
chr14:75624170(-) A-I      intronic
chr14:75602934(-) A-I      intronic
chr14:75604440(-) A-I      intronic
chr14:75630907(-) A-I      intronic
chr14:75625564(-) A-I      intronic
chr14:75625596(-) A-I      intronic
chr14:75607022(-) A-I      intronic
chr14:75616738(-) A-I      intronic
chr14:75611643(-) A-I      intronic
chr14:75625230(-) A-I      intronic
chr14:75610374(-) A-I      intronic
chr14:75625258(-) A-I      intronic
chr14:75607244(-) A-I      intronic
chr14:75621800(-) A-I      intronic
chr14:75636741(-) A-I      intronic
chr14:75619557(-) A-I      intronic
chr14:75607359(-) A-I      intronic
chr14:75615884(-) A-I      intronic
chr14:75620611(-) A-I      intronic
chr14:75632036(-) A-I      intronic
chr14:75604549(-) A-I      intronic
chr14:75617744(-) A-I      intronic
chr14:75609629(-) A-I      intronic
chr14:75606941(-) A-I      intronic
chr14:75616799(-) A-I      intronic
chr14:75603919(-) A-I      intronic
chr14:75639995(-) A-I      intronic
chr14:75625565(-) A-I      intronic
chr14:75609841(-) A-I      intronic
chr14:75604536(-) A-I      intronic
chr14:75610537(-) A-I      intronic
chr14:75604560(-) A-I      intronic
chr14:75619662(-) A-I      intronic
chr14:75615698(-) A-I      intronic
chr14:75616563(-) A-I      intronic
chr14:75630845(-) A-I      intronic
chr14:75604556(-) A-I      intronic
chr14:75598942(-) A-I      3'UTR
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED TMED10
chr14:75609629(-) A-I intron -    22327324
chr14:75599099(-) G-T exon 3'UTR    22484847
chr14:75599100(-) T-G exon 3'UTR    22484847
chr14:75603987(-) T-C intron -    22484847
chr14:75604536(-) A-G intron -    22484847
chr14:75604549(-) A-G intron -    22484847
chr14:75604550(-) A-G intron -    22484847
chr14:75604560(-) A-G intron -    22484847
chr14:75609584(-) A-G intron -    22484847
chr14:75609629(-) A-G intron -    22484847
chr14:75611565(-) A-G intron -    22484847
chr14:75625230(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase TMED10
chr14:75599700-75599701(-) m6A 3'UTR       26404942
chr14:75599797-75599798(-) m6A 3'UTR       24981863//26404942
chr14:75600864-75600865(-) m6A 3'UTR//exon       27773535
chr14:75600869-75600870(-) m6A 3'UTR//exon       27773535
chr14:75601012-75601013(-) m6A 3'UTR//exon       27773535
chr14:75601135-75601136(-) m6A 3'UTR//exon       -
chr14:75601261-75601262(-) m6A 3'UTR//exon       24284625//27773535//22575960
chr14:75601403-75601404(-) m6A 3'UTR//exon       24284625//25456834//24981863//28052920//27773535//27371828//22575960//22608085
chr14:75601441-75601442(-) m6A 3'UTR//exon       24284625//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr14:75601465-75601466(-) m6A 3'UTR//exon       24284625//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr14:75601541-75601542(-) m6A 3'UTR//exon       24284625//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr14:75601650-75601651(-) m6A 3'UTR//CDS//exon       24284625
chr14:75601699-75601700(-) m6A 3'UTR//CDS//exon       24284625
chr14:75602404-75602405(-) m6A exon//intron       24284625
chr14:75602533-75602534(-) m6A 3'UTR//CDS//exon       24981863
chr14:75602565-75602566(-) m6A 3'UTR//CDS//exon       24981863
chr14:75605784-75605785(-) m6A 3'UTR//intron       24981863
chr14:75614403-75614404(-) m6A CDS//exon       24981863//27773535
chr14:75614437-75614438(-) m6A CDS//exon       24981863//27773535
chr14:75643308-75643309(-) Y 5'UTR//exon       26075521

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate TMED10
Chromatin K562 cells     -
Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539
Exosome Blood     -
Nucleoplasm K562 cells     -
Ribosome HEK-293 cells     22199352
Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):


Interactor1: hcmv-miR-US25-1-5p
Interactor2: TMED10

Evidence Support:


Strong-Evidence RISC-IP
Support Database ViRBase

References:


PMID 20585629 Target region 5'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line HEK293 cells Interactor2 expression None
Description Here, we identify cellular transcript targets of one of the most highly expressed HCMV encoded miRNAs, miR-US25-1, using a recently developed biochemical approach called RISC immunoprecipitation. Strikingly, the majority of identified transcripts contained miR-US25-1 target sites within the 5'UTR rather than the 3'UTR.

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