Detail Information

Basic Information:


  VIRBase ID:  

VHID00508179

  Virus:  

Human herpesvirus 5 strain AD169

  Host:  

Homo sapiens

  Confidence Score:  

0.7311

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-US25-1-5p:           MRPS31:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hcmv-miR-US25-1-5p MRPS31
miRBase
Accession/Entrez ID		 MIMAT0001581 10240
Organism Human herpesvirus 5 strain AD169 Homo sapiens
Category miRNA mRNA
Alias - IMOGN38//MRP-S31//S31mt

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR MRPS31
chr13:41327003(-) A-I      intronic
chr13:41304598(-) A-I      intronic
chr13:41327012(-) A-I      intronic
chr13:41304553(-) A-I      intronic
chr13:41327013(-) A-I      intronic
chr13:41327031(-) A-I      intronic
chr13:41304537(-) A-I      intronic
chr13:41326977(-) A-I      intronic
chr13:41306653(-) A-I      intronic
chr13:41326983(-) A-I      intronic
chr13:41326989(-) A-I      intronic
chr13:41326995(-) A-I      intronic
chr13:41305358(-) A-I      intronic
chr13:41322517(-) A-I      intronic
chr13:41322454(-) A-I      intronic
chr13:41322448(-) A-I      intronic
chr13:41329058(-) A-I      intronic
chr13:41322447(-) A-I      intronic
chr13:41322399(-) A-I      intronic
chr13:41322391(-) A-I      intronic
chr13:41322376(-) A-I      intronic
chr13:41321848(-) A-I      intronic
chr13:41321822(-) A-I      intronic
chr13:41321371(-) A-I      intronic
chr13:41321369(-) A-I      intronic
chr13:41319661(-) A-I      intronic
chr13:41319634(-) A-I      intronic
chr13:41319581(-) A-I      intronic
chr13:41319251(-) A-I      intronic
chr13:41334877(-) A-I      intronic
chr13:41308908(-) A-I      intronic
chr13:41308165(-) A-I      intronic
chr13:41308064(-) A-I      intronic
chr13:41308051(-) A-I      intronic
chr13:41306824(-) A-I      intronic
chr13:41304578(-) A-I      intronic
chr13:41306836(-) A-I      intronic
chr13:41307869(-) A-I      intronic
chr13:41304575(-) A-I      intronic
chr13:41342801(-) A-I      intronic
chr13:41304440(-) A-I      intronic
chr13:41305268(-) A-I      intronic
chr13:41304402(-) A-I      intronic
chr13:41304139(-) A-I      intronic
chr13:41304093(-) A-I      intronic
chr13:41303954(-) A-I      intronic
chr13:41303911(-) A-I      intronic
chr13:41304968(-) A-I      intronic
chr13:41321897(-) A-I      intronic
chr13:41305712(-) A-I      intronic
chr13:41307232(-) A-I      intronic
chr13:41307236(-) A-I      intronic
chr13:41307278(-) A-I      intronic
chr13:41342622(-) A-I      intronic
chr13:41343349(-) A-I      intronic
chr13:41304561(-) A-I      intronic
chr13:41306754(-) A-I      intronic
chr13:41306761(-) A-I      intronic
chr13:41304601(-) A-I      intronic
chr13:41336741(-) A-I      intronic
chr13:41336296(-) A-I      intronic
chr13:41336295(-) A-I      intronic
chr13:41332476(-) A-I      intronic
chr13:41304512(-) A-I      intronic
chr13:41304904(-) A-I      intronic
chr13:41307372(-) A-I      intronic
chr13:41336195(-) A-I      intronic
chr13:41306730(-) A-I      intronic
chr13:41331719(-) A-I      intronic
chr13:41305163(-) A-I      intronic
chr13:41329126(-) A-I      intronic
chr13:41307304(-) A-I      intronic
chr13:41322520(-) A-I      intronic
chr13:41306626(-) A-I      intronic
chr13:41306667(-) A-I      intronic
chr13:41307941(-) A-I      intronic
chr13:41307952(-) A-I      intronic
chr13:41342695(-) A-I      intronic
chr13:41304975(-) A-I      intronic
chr13:41304793(-) A-I      intronic
chr13:41306652(-) A-I      intronic
chr13:41336186(-) A-I      intronic
chr13:41334898(-) A-I      intronic
chr13:41334867(-) A-I      intronic
chr13:41306875(-) A-I      intronic
chr13:41307277(-) A-I      intronic
chr13:41304478(-) A-I      intronic
chr13:41304415(-) A-I      intronic
chr13:41321380(-) A-I      intronic
chr13:41305295(-) A-I      intronic
chr13:41333488(-) A-I      intronic
chr13:41329048(-) A-I      intronic
chr13:41306748(-) A-I      intronic
chr13:41308183(-) A-I      intronic
chr13:41322390(-) A-I      intronic
chr13:41304436(-) A-I      intronic
chr13:41336672(-) A-I      intronic
chr13:41306625(-) A-I      intronic
chr13:41321896(-) A-I      intronic
chr13:41304495(-) A-I      intronic
chr13:41336750(-) A-I      intronic
chr13:41319154(-) A-I      intronic
chr13:41334903(-) A-I      intronic
chr13:41305618(-) A-I      intronic
chr13:41336212(-) A-I      intronic
chr13:41304513(-) A-I      intronic
chr13:41340513(-) A-I      intronic
chr13:41336790(-) A-I      intronic
chr13:41304414(-) A-I      intronic
chr13:41334860(-) A-I      intronic
chr13:41304486(-) A-I      intronic
chr13:41304794(-) A-I      intronic
chr13:41336749(-) A-I      intronic
chr13:41336845(-) A-I      intronic
chr13:41322432(-) A-I      intronic
chr13:41304453(-) A-I      intronic
chr13:41303957(-) A-I      intronic
chr13:41336266(-) A-I      intronic
chr13:41333356(-) A-I      intronic
chr13:41326168(-) A-I      intronic
chr13:41304982(-) A-I      intronic
chr13:41305445(-) A-I      intronic
chr13:41307834(-) A-I      intronic
chr13:41321769(-) A-I      intronic
chr13:41336791(-) A-I      intronic
chr13:41322418(-) A-I      intronic
chr13:41319607(-) A-I      intronic
chr13:41304835(-) A-I      intronic
chr13:41304985(-) A-I      intronic
chr13:41304577(-) A-I      intronic
chr13:41305242(-) A-I      intronic
chr13:41336748(-) A-I      intronic
chr13:41321300(-) A-I      intronic
chr13:41336681(-) A-I      intronic
chr13:41306822(-) A-I      intronic
chr13:41304549(-) A-I      intronic
chr13:41304539(-) A-I      intronic
chr13:41336694(-) A-I      intronic
chr13:41304138(-) A-I      intronic
chr13:41306817(-) A-I      intronic
chr13:41304901(-) A-I      intronic
chr13:41306738(-) A-I      intronic
chr13:41336287(-) A-I      intronic
chr13:41322559(-) A-I      intronic
chr13:41322469(-) A-I      intronic
chr13:41307919(-) A-I      intronic
chr13:41307984(-) A-I      intronic
chr13:41336270(-) A-I      intronic
chr13:41321851(-) A-I      intronic
chr13:41322486(-) A-I      intronic
chr13:41304900(-) A-I      intronic
chr13:41306812(-) A-I      intronic
chr13:41334852(-) A-I      intronic
chr13:41319606(-) A-I      intronic
chr13:41343449(-) A-I      intronic
chr13:41306746(-) A-I      intronic
chr13:41305666(-) A-I      intronic
chr13:41343429(-) A-I      intronic
chr13:41329061(-) A-I      intronic
chr13:41306648(-) A-I      intronic
chr13:41308182(-) A-I      intronic
chr13:41340568(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED MRPS31
chr13:41304835(-) A-G intron -    22484847
chr13:41334898(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase MRPS31
chr13:41328157-41328158(-) m6A CDS       27773535
chr13:41328203-41328204(-) m6A CDS       24981863//27773535
chr13:41331085-41331086(-) m6A CDS       24981863//27773535
chr13:41340949-41340950(-) m6A CDS//exon       24284625//24981863//27773535//22608085
chr13:41340972-41340973(-) m6A CDS//exon       24284625//24981863//28052920//27773535//22608085
chr13:41341028-41341029(-) m6A CDS//exon       24284625//24981863//28052920//27773535//22608085
chr13:41341055-41341056(-) m6A CDS//exon       24284625//24981863//28052920//27773535//22608085
chr13:41341071-41341072(-) m6A CDS//exon       24284625//24981863//28052920//27773535//22608085
chr13:41341083-41341084(-) m6A CDS//exon       24284625//24981863//28052920//27773535//22608085
chr13:41341092-41341093(-) m6A CDS//exon       24284625//24981863//28052920//27773535//22608085

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate MRPS31
Exosome Blood     -
Membrane HCC cell line (HepG2)     -
Nucleoplasm K562 cells     -

Interaction Network (The top 100 interactions):


Interactor1: hcmv-miR-US25-1-5p
Interactor2: MRPS31

Evidence Support:


Strong-Evidence RISC-IP
Support Database ViRBase

References:


PMID 20585629 Target region 5'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line HEK293 cells Interactor2 expression None
Description Here, we identify cellular transcript targets of one of the most highly expressed HCMV encoded miRNAs, miR-US25-1, using a recently developed biochemical approach called RISC immunoprecipitation. Strikingly, the majority of identified transcripts contained miR-US25-1 target sites within the 5'UTR rather than the 3'UTR.

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