Detail Information

Basic Information:


  VIRBase ID:  

VHID00506188

  Virus:  

Human herpesvirus 5 strain AD169

  Host:  

Homo sapiens

  Confidence Score:  

0.7311

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-US25-1-5p:           TMF1:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hcmv-miR-US25-1-5p TMF1
miRBase
Accession/Entrez ID		 MIMAT0001581 7110
Organism Human herpesvirus 5 strain AD169 Homo sapiens
Category miRNA mRNA
Alias - ARA160//TMF

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR TMF1
chr3:69076374(-) A-I      intronic
chr3:69076373(-) A-I      intronic
chr3:69076363(-) A-I      intronic
chr3:69076411(-) A-I      intronic
chr3:69076351(-) A-I      intronic
chr3:69076348(-) A-I      intronic
chr3:69076303(-) A-I      intronic
chr3:69076295(-) A-I      intronic
chr3:69076284(-) A-I      intronic
chr3:69076223(-) A-I      intronic
chr3:69075752(-) A-I      intronic
chr3:69075719(-) A-I      intronic
chr3:69075668(-) A-I      intronic
chr3:69075635(-) A-I      intronic
chr3:69075603(-) A-I      intronic
chr3:69075599(-) A-I      intronic
chr3:69075598(-) A-I      intronic
chr3:69075585(-) A-I      intronic
chr3:69075582(-) A-I      intronic
chr3:69075575(-) A-I      intronic
chr3:69075531(-) A-I      intronic
chr3:69075503(-) A-I      intronic
chr3:69081925(-) A-I      intronic
chr3:69075556(-) A-I      intronic
chr3:69091483(-) A-I      intronic
chr3:69091416(-) A-I      intronic
chr3:69091403(-) A-I      intronic
chr3:69091402(-) A-I      intronic
chr3:69088446(-) A-I      intronic
chr3:69088401(-) A-I      intronic
chr3:69086618(-) A-I      intronic
chr3:69083237(-) A-I      intronic
chr3:69083210(-) A-I      intronic
chr3:69083206(-) A-I      intronic
chr3:69082411(-) A-I      intronic
chr3:69082362(-) A-I      intronic
chr3:69082303(-) A-I      intronic
chr3:69082034(-) A-I      intronic
chr3:69081867(-) A-I      intronic
chr3:69081847(-) A-I      intronic
chr3:69076438(-) A-I      intronic
chr3:69076419(-) A-I      intronic
chr3:69075681(-) A-I      intronic
chr3:69076405(-) A-I      intronic
chr3:69076393(-) A-I      intronic
chr3:69071039(-) A-I      3'UTR
chr3:69070899(-) A-I      3'UTR
chr3:69071045(-) A-I      3'UTR
chr3:69070900(-) A-I      3'UTR
chr3:69070996(-) A-I      3'UTR
chr3:69071027(-) A-I      3'UTR
chr3:69071000(-) A-I      3'UTR
chr3:69071014(-) A-I      3'UTR
chr3:69071025(-) A-I      3'UTR
chr3:69071054(-) A-I      3'UTR
chr3:69071005(-) A-I      3'UTR
chr3:69070999(-) A-I      3'UTR
chr3:69071001(-) A-I      3'UTR
chr3:69071062(-) A-I      3'UTR
chr3:69071002(-) A-I      3'UTR
chr3:69083239(-) A-I      intronic
chr3:69081898(-) A-I      intronic
chr3:69075680(-) A-I      intronic
chr3:69100514(-) A-I      intronic
chr3:69076311(-) A-I      intronic
chr3:69070910(-) A-I      3'UTR
chr3:69070943(-) A-I      3'UTR
chr3:69070970(-) A-I      3'UTR
chr3:69070907(-) A-I      3'UTR
chr3:69075560(-) A-I      intronic
chr3:69076426(-) A-I      intronic
chr3:69075555(-) A-I      intronic
chr3:69082058(-) A-I      intronic
chr3:69081899(-) A-I      intronic
chr3:69076350(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED TMF1
chr3:69070904(-) A-I exon 3'UTR    15258596
chr3:69070907(-) A-I exon 3'UTR    15258596
chr3:69070910(-) A-I exon 3'UTR    15258596
chr3:69070943(-) A-I exon 3'UTR    15258596
chr3:69070960(-) A-I exon 3'UTR    15258596
chr3:69070969(-) A-I exon 3'UTR    15258596
chr3:69070970(-) A-I exon 3'UTR    15258596

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase TMF1
chr3:69069061-69069062(-) m6A 3'UTR       27773535
chr3:69069104-69069105(-) m6A 3'UTR       27773535
chr3:69069113-69069114(-) m6A 3'UTR       27773535
chr3:69070317-69070318(-) m6A 3'UTR       27773535
chr3:69070335-69070336(-) m6A 3'UTR       27773535
chr3:69070349-69070350(-) m6A 3'UTR       27773535
chr3:69072124-69072125(-) m6A 3'UTR       27773535
chr3:69072138-69072139(-) m6A 3'UTR       27773535
chr3:69072262-69072263(-) m6A 3'UTR       24981863//27773535//22608085
chr3:69072275-69072276(-) m6A 3'UTR       24981863//27773535//22608085
chr3:69072301-69072302(-) m6A 3'UTR       24981863//27773535//22608085
chr3:69072342-69072343(-) m6A 3'UTR//CDS       24981863//27773535//22608085
chr3:69072351-69072352(-) m6A 3'UTR//CDS       24981863//27773535//22608085
chr3:69072365-69072366(-) m6A 3'UTR//CDS       24981863//28052920//27773535//22608085
chr3:69072405-69072406(-) m6A 3'UTR//CDS       24981863//28052920//27773535//22608085
chr3:69073216-69073217(-) m6A 3'UTR//CDS       24981863//28052920//27773535//22608085
chr3:69073223-69073224(-) m6A 3'UTR//CDS       24981863//28052920//27773535//22608085
chr3:69073253-69073254(-) m6A 3'UTR//CDS       24981863//28052920//27773535//22608085
chr3:69073283-69073284(-) m6A 3'UTR//CDS       24981863//28052920//27773535//22608085
chr3:69073306-69073307(-) m6A 3'UTR//CDS       24981863//28052920//27773535//22608085
chr3:69073507-69073508(-) m6A exon//intron       24981863//27773535
chr3:69073542-69073543(-) m6A exon//intron       24981863
chr3:69074759-69074760(-) m6A 3'UTR//CDS//exon       24981863
chr3:69077064-69077065(-) m6A 3'UTR//CDS       24981863//27773535
chr3:69077098-69077099(-) m6A 3'UTR//CDS       24981863//27773535
chr3:69077402-69077403(-) m6A 3'UTR//CDS       24981863//27773535
chr3:69077425-69077426(-) m6A 3'UTR//CDS       24981863//27773535
chr3:69078971-69078972(-) m6A 3'UTR//CDS       24981863//27773535
chr3:69078985-69078986(-) m6A 3'UTR//CDS       24981863//27773535
chr3:69079034-69079035(-) m6A 3'UTR//CDS       24981863//27773535
chr3:69079042-69079043(-) m6A 3'UTR//CDS       24981863//27773535
chr3:69079099-69079100(-) m6A CDS       27773535
chr3:69079146-69079147(-) m6A CDS//intron       27773535
chr3:69082743-69082744(-) m6A CDS//intron       24981863//27773535//27371828
chr3:69082792-69082793(-) m6A CDS//intron       24981863//27773535//27371828
chr3:69082822-69082823(-) m6A CDS//intron       24981863//27773535//27371828
chr3:69082829-69082830(-) m6A CDS//intron       24981863//27773535//27371828
chr3:69082852-69082853(-) m6A CDS//intron       24981863//27773535
chr3:69084182-69084183(-) m6A CDS       24981863//27773535
chr3:69084230-69084231(-) m6A CDS       24981863//27773535
chr3:69084258-69084259(-) m6A CDS       24981863//27773535
chr3:69087728-69087729(-) m6A CDS       27773535
chr3:69087780-69087781(-) m6A CDS       27773535
chr3:69087867-69087868(-) m6A CDS       27773535
chr3:69088029-69088030(-) m6A CDS       27773535
chr3:69088043-69088044(-) m6A CDS       27773535
chr3:69088053-69088054(-) m6A CDS       27773535
chr3:69088106-69088107(-) m6A CDS       24981863//28052920//27773535//22608085
chr3:69088130-69088131(-) m6A CDS       24981863//28052920//27773535//22608085
chr3:69088704-69088705(-) m6A CDS       24981863//28052920//27773535//22575960//22608085
chr3:69088747-69088748(-) m6A CDS       24981863//28052920//27773535//22575960//22608085
chr3:69088780-69088781(-) m6A CDS       24981863//27773535//22575960//22608085
chr3:69088827-69088828(-) m6A CDS       24981863//27773535//22575960
chr3:69088836-69088837(-) m6A CDS       24981863//27773535//22575960
chr3:69092004-69092005(-) m6A CDS       24981863//27773535//22575960
chr3:69092011-69092012(-) m6A CDS       24981863//27773535//22575960
chr3:69092039-69092040(-) m6A CDS       24981863//27773535
chr3:69092052-69092053(-) m6A CDS       24981863//27773535
chr3:69093745-69093746(-) m6A CDS//exon       24284625//25456834//24981863//27773535//22608085
chr3:69096559-69096560(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22608085
chr3:69096581-69096582(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22608085
chr3:69096595-69096596(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22608085
chr3:69096637-69096638(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//27773535//22608085
chr3:69096708-69096709(-) m6A CDS       24284625//24209618//24981863//27773535//22608085
chr3:69096750-69096751(-) m6A CDS       24284625//24209618//24981863//27773535//22608085
chr3:69096875-69096876(-) m6A CDS       24284625//24209618//24981863//26404942//27773535//22575960//22608085
chr3:69096919-69096920(-) m6A CDS       24284625//24209618//24981863//26404942//27773535//22575960//22608085
chr3:69096984-69096985(-) m6A CDS       24284625//24209618//24981863//27773535//22575960//22608085
chr3:69097020-69097021(-) m6A CDS       24284625//24981863//27773535//22575960//22608085
chr3:69097027-69097028(-) m6A CDS       24284625//24981863//27773535//22575960//22608085
chr3:69097148-69097149(-) m6A CDS       24284625//24209618//24981863//27773535//22575960//22608085
chr3:69097156-69097157(-) m6A CDS       24284625//24209618//24981863//27773535//22575960//22608085
chr3:69097162-69097163(-) m6A CDS       24284625//24209618//24981863//27773535//22575960//22608085
chr3:69097171-69097172(-) m6A CDS       24284625//24209618//24981863//27773535//22575960//22608085
chr3:69097184-69097185(-) m6A CDS       24284625//24209618//24981863//26404942//27773535//27371828//22575960//22608085
chr3:69097191-69097192(-) m6A CDS       24284625//24209618//24981863//26404942//27773535//27371828//22575960//22608085
chr3:69097242-69097243(-) m6A CDS       24284625//24209618//24981863//26404942//27773535//27371828//22575960//22608085
chr3:69097317-69097318(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr3:69097338-69097339(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr3:69097368-69097369(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr3:69097394-69097395(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr3:69097416-69097417(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr3:69097425-69097426(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr3:69097504-69097505(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22608085
chr3:69097533-69097534(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22608085
chr3:69097593-69097594(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22608085
chr3:69097648-69097649(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22608085
chr3:69097655-69097656(-) m6A CDS       24284625//24981863//27773535//27371828//27773536//22608085
chr3:69101343-69101344(-) m6A 5'UTR       24981863//27371828//27773536

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate TMF1
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Cytosol HCC cell line (HepG2)     -
Exosome Blood     -
Nucleolus K562 cells     -
Nucleus HCC cell line (HepG2)|K562 cells     -

Interaction Network (The top 100 interactions):


Interactor1: hcmv-miR-US25-1-5p
Interactor2: TMF1

Evidence Support:


Strong-Evidence RISC-IP
Support Database ViRBase

References:


PMID 20585629 Target region 5'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line HEK293 cells Interactor2 expression None
Description Here, we identify cellular transcript targets of one of the most highly expressed HCMV encoded miRNAs, miR-US25-1, using a recently developed biochemical approach called RISC immunoprecipitation. Strikingly, the majority of identified transcripts contained miR-US25-1 target sites within the 5'UTR rather than the 3'UTR.

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