Detail Information

Basic Information:


  VIRBase ID:  

VHID00504423

  Virus:  

Human herpesvirus 5 strain AD169

  Host:  

Homo sapiens

  Confidence Score:  

0.7311

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-US25-1-5p:           MYO10:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hcmv-miR-US25-1-5p MYO10
miRBase
Accession/Entrez ID		 MIMAT0001581 4651
Organism Human herpesvirus 5 strain AD169 Homo sapiens
Category miRNA mRNA
Alias - -

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR MYO10
chr5:16774583(-) A-I      intronic
chr5:16770994(-) A-I      intronic
chr5:16767796(-) A-I      intronic
chr5:16762008(-) A-I      intronic
chr5:16761168(-) A-I      intronic
chr5:16757895(-) A-I      intronic
chr5:16757858(-) A-I      intronic
chr5:16757850(-) A-I      intronic
chr5:16757848(-) A-I      intronic
chr5:16757361(-) A-I      intronic
chr5:16757159(-) A-I      intronic
chr5:16756992(-) A-I      intronic
chr5:16756418(-) A-I      intronic
chr5:16756402(-) A-I      intronic
chr5:16756306(-) A-I      intronic
chr5:16756244(-) A-I      intronic
chr5:16755477(-) A-I      intronic
chr5:16752619(-) A-I      intronic
chr5:16752468(-) A-I      intronic
chr5:16752459(-) A-I      intronic
chr5:16751719(-) A-I      intronic
chr5:16748536(-) A-I      intronic
chr5:16748533(-) A-I      intronic
chr5:16748532(-) A-I      intronic
chr5:16748294(-) A-I      intronic
chr5:16725445(-) A-I      intronic
chr5:16725409(-) A-I      intronic
chr5:16725408(-) A-I      intronic
chr5:16725398(-) A-I      intronic
chr5:16725352(-) A-I      intronic
chr5:16725334(-) A-I      intronic
chr5:16725333(-) A-I      intronic
chr5:16725320(-) A-I      intronic
chr5:16725312(-) A-I      intronic
chr5:16717107(-) A-I      intronic
chr5:16715640(-) A-I      intronic
chr5:16715628(-) A-I      intronic
chr5:16715612(-) A-I      intronic
chr5:16715603(-) A-I      intronic
chr5:16715602(-) A-I      intronic
chr5:16715597(-) A-I      intronic
chr5:16715582(-) A-I      intronic
chr5:16715570(-) A-I      intronic
chr5:16714820(-) A-I      intronic
chr5:16714813(-) A-I      intronic
chr5:16696853(-) A-I      intronic
chr5:16686804(-) A-I      intronic
chr5:16686802(-) A-I      intronic
chr5:16685520(-) A-I      intronic
chr5:16685388(-) A-I      intronic
chr5:16684496(-) A-I      intronic
chr5:16684437(-) A-I      intronic
chr5:16747470(-) A-I      intronic
chr5:16817085(-) A-I      intronic
chr5:16687286(-) A-I      intronic
chr5:16687348(-) A-I      intronic
chr5:16732992(-) A-I      intronic
chr5:16751021(-) A-I      intronic
chr5:16751861(-) A-I      intronic
chr5:16756975(-) A-I      intronic
chr5:16757165(-) A-I      intronic
chr5:16757353(-) A-I      intronic
chr5:16811095(-) A-I      intronic
chr5:16816866(-) A-I      intronic
chr5:16876896(-) A-I      intronic
chr5:16908452(-) A-I      intronic
chr5:16923024(-) A-I      intronic
chr5:16925672(-) A-I      intronic
chr5:16926686(-) A-I      intronic
chr5:16725356(-) A-I      intronic
chr5:16756447(-) A-I      intronic
chr5:16756448(-) A-I      intronic
chr5:16757834(-) A-I      intronic
chr5:16757898(-) A-I      intronic
chr5:16757902(-) A-I      intronic
chr5:16817093(-) A-I      intronic
chr5:16817096(-) A-I      intronic
chr5:16817097(-) A-I      intronic
chr5:16817108(-) A-I      intronic
chr5:16817153(-) A-I      intronic
chr5:16823454(-) A-I      intronic
chr5:16823461(-) A-I      intronic
chr5:16823471(-) A-I      intronic
chr5:16823494(-) A-I      intronic
chr5:16823497(-) A-I      intronic
chr5:16848487(-) A-I      intronic
chr5:16848488(-) A-I      intronic
chr5:16848506(-) A-I      intronic
chr5:16848518(-) A-I      intronic
chr5:16928441(-) A-I      intronic
chr5:16925078(-) A-I      intronic
chr5:16923592(-) A-I      intronic
chr5:16923580(-) A-I      intronic
chr5:16922974(-) A-I      intronic
chr5:16922968(-) A-I      intronic
chr5:16919449(-) A-I      intronic
chr5:16919443(-) A-I      intronic
chr5:16847763(-) A-I      intronic
chr5:16847762(-) A-I      intronic
chr5:16826211(-) A-I      intronic
chr5:16826149(-) A-I      intronic
chr5:16823442(-) A-I      intronic
chr5:16823426(-) A-I      intronic
chr5:16823371(-) A-I      intronic
chr5:16823362(-) A-I      intronic
chr5:16821848(-) A-I      intronic
chr5:16821847(-) A-I      intronic
chr5:16816778(-) A-I      intronic
chr5:16816777(-) A-I      intronic
chr5:16816751(-) A-I      intronic
chr5:16805409(-) A-I      intronic
chr5:16776243(-) A-I      intronic
chr5:16776169(-) A-I      intronic
chr5:16662687(-) A-I      3'UTR
chr5:16662698(-) A-I      3'UTR
chr5:16662548(-) A-I      3'UTR
chr5:16662726(-) A-I      3'UTR
chr5:16663729(-) A-I      3'UTR
chr5:16662525(-) A-I      3'UTR
chr5:16662509(-) A-I      3'UTR
chr5:16665298(-) A-I      3'UTR
chr5:16662597(-) A-I      3'UTR
chr5:16662613(-) A-I      3'UTR
chr5:16662517(-) A-I      3'UTR
chr5:16662463(-) A-I      3'UTR
chr5:16665312(-) A-I      3'UTR
chr5:16662703(-) A-I      3'UTR
chr5:16678492(-) A-I      intronic
chr5:16823653(-) A-I      intronic
chr5:16816276(-) A-I      intronic
chr5:16753753(-) A-I      intronic
chr5:16888420(-) A-I      intronic
chr5:16778054(-) A-I      intronic
chr5:16869770(-) A-I      intronic
chr5:16823391(-) A-I      intronic
chr5:16685458(-) A-I      intronic
chr5:16720659(-) A-I      intronic
chr5:16686799(-) A-I      intronic
chr5:16753453(-) A-I      intronic
chr5:16816822(-) A-I      intronic
chr5:16823406(-) A-I      intronic
chr5:16826174(-) A-I      intronic
chr5:16756310(-) A-I      intronic
chr5:16753758(-) A-I      intronic
chr5:16926764(-) A-I      intronic
chr5:16662607(-) A-I      3'UTR
chr5:16662571(-) A-I      3'UTR
chr5:16663700(-) A-I      3'UTR
chr5:16662634(-) A-I      3'UTR
chr5:16665144(-) A-I      3'UTR
chr5:16662565(-) A-I      3'UTR
chr5:16662501(-) A-I      3'UTR
chr5:16662540(-) A-I      3'UTR
chr5:16665190(-) A-I      3'UTR
chr5:16665188(-) A-I      3'UTR
chr5:16662515(-) A-I      3'UTR
chr5:16665073(-) A-I      3'UTR
chr5:16662704(-) A-I      3'UTR
chr5:16665212(-) A-I      3'UTR
chr5:16665095(-) A-I      3'UTR
chr5:16662538(-) A-I      3'UTR
chr5:16725301(-) A-I      intronic
chr5:16748385(-) A-I      intronic
chr5:16920336(-) A-I      intronic
chr5:16747861(-) A-I      intronic
chr5:16698297(-) A-I      intronic
chr5:16747838(-) A-I      intronic
chr5:16756434(-) A-I      intronic
chr5:16714739(-) A-I      intronic
chr5:16896655(-) A-I      intronic
chr5:16731730(-) A-I      intronic
chr5:16821714(-) A-I      intronic
chr5:16923468(-) A-I      intronic
chr5:16778114(-) A-I      intronic
chr5:16685398(-) A-I      intronic
chr5:16685133(-) A-I      intronic
chr5:16753803(-) A-I      intronic
chr5:16757316(-) A-I      intronic
chr5:16698439(-) A-I      intronic
chr5:16835523(-) A-I      intronic
chr5:16876100(-) A-I      intronic
chr5:16685498(-) A-I      intronic
chr5:16855103(-) A-I      intronic
chr5:16731549(-) A-I      intronic
chr5:16816865(-) A-I      intronic
chr5:16823876(-) A-I      intronic
chr5:16751728(-) A-I      intronic
chr5:16751707(-) A-I      intronic
chr5:16678648(-) A-I      intronic
chr5:16697665(-) A-I      intronic
chr5:16747864(-) A-I      intronic
chr5:16816282(-) A-I      intronic
chr5:16757116(-) A-I      intronic
chr5:16848364(-) A-I      intronic
chr5:16771813(-) A-I      intronic
chr5:16698437(-) A-I      intronic
chr5:16698356(-) A-I      intronic
chr5:16870944(-) A-I      intronic
chr5:16685448(-) A-I      intronic
chr5:16743495(-) A-I      intronic

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase MYO10
chr5:16665457-16665458(-) m6A 3'UTR       24284625//24981863//22608085
chr5:16665528-16665529(-) m6A 3'UTR       24284625//24981863//22575960//22608085
chr5:16665560-16665561(-) m6A 3'UTR       24284625//24981863//22575960//22608085
chr5:16665619-16665620(-) m6A 3'UTR       24284625//24981863//22575960//22608085
chr5:16665687-16665688(-) m6A 3'UTR       24284625//24209618//24981863//22575960//22608085
chr5:16665815-16665816(-) m6A 3'UTR       24284625//24981863//26404942//22608085
chr5:16666188-16666189(-) m6A 3'UTR       24284625//24209618//25456834
chr5:16666308-16666309(-) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//22575960//22608085
chr5:16666427-16666428(-) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//22575960//22608085
chr5:16666452-16666453(-) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//22575960//22608085
chr5:16666490-16666491(-) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//22575960//22608085
chr5:16666534-16666535(-) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//22575960//22608085
chr5:16666562-16666563(-) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085
chr5:16666713-16666714(-) m6A 3'UTR       24284625//25456834//24981863//26404942//22575960
chr5:16666792-16666793(-) m6A 3'UTR       24284625//25456834//24981863//26404942
chr5:16668393-16668394(-) m6A CDS       24284625
chr5:16668469-16668470(-) m6A CDS       24284625
chr5:16668493-16668494(-) m6A CDS       24284625
chr5:16668550-16668551(-) m6A CDS       24284625//22575960
chr5:16670706-16670707(-) m6A CDS       24284625//26404942//22575960
chr5:16670713-16670714(-) m6A CDS       24284625//26404942//22575960
chr5:16670788-16670789(-) m6A CDS       24284625//24981863//26404942//22575960
chr5:16670813-16670814(-) Am CDS       -
chr5:16670834-16670835(-) m6A CDS       24284625//24981863//26404942//22575960
chr5:16670855-16670856(-) m6A CDS       24284625//24981863//26404942//22575960
chr5:16670909-16670910(-) m6A CDS       24284625//24981863//26404942//22575960
chr5:16670940-16670941(-) m6A CDS       24284625//24981863//26404942
chr5:16671040-16671041(-) m6A CDS       24284625//26404942
chr5:16671533-16671534(-) m6A CDS       26404942
chr5:16671561-16671562(-) m6A CDS       26404942
chr5:16671576-16671577(-) m6A CDS       26404942
chr5:16671582-16671583(-) m6A CDS       26404942
chr5:16671599-16671600(-) m6A CDS       26404942
chr5:16671624-16671625(-) m6A CDS       26404942
chr5:16673927-16673928(-) m6A CDS       26404942
chr5:16675142-16675143(-) m6A CDS       26404942
chr5:16675249-16675250(-) m6A CDS       26404942
chr5:16676153-16676154(-) m6A CDS       26404942
chr5:16676216-16676217(-) m6A CDS       26404942
chr5:16676233-16676234(-) m6A CDS       26404942
chr5:16676249-16676250(-) m6A CDS       26404942
chr5:16676258-16676259(-) m6A CDS       26404942
chr5:16681587-16681588(-) m6A CDS       26404942
chr5:16682014-16682015(-) m6A CDS       24284625//26404942//22575960
chr5:16685862-16685863(-) m6A CDS       24284625//22575960
chr5:16685898-16685899(-) m6A CDS       24284625//22575960
chr5:16689969-16689970(-) m6A CDS       26404942
chr5:16694478-16694479(-) Gm intron       -
chr5:16699662-16699663(-) m6A CDS       24284625
chr5:16701124-16701125(-) m6A CDS       24284625//26404942//22575960
chr5:16701261-16701262(-) m6A CDS       24284625//24209618//25456834//24981863//26404942//22575960//22608085
chr5:16701327-16701328(-) m6A CDS       24284625//24209618//25456834//24981863//26404942//22575960//22608085
chr5:16701360-16701361(-) m6A CDS       24284625//24209618//25456834//24981863//26404942//22575960//22608085
chr5:16701405-16701406(-) m6A CDS       24284625//24209618//25456834//24981863//26404942//27773536//22575960//22608085
chr5:16701430-16701431(-) m6A CDS       24284625//24209618//25456834//24981863//26404942//27773536//22575960//22608085
chr5:16701445-16701446(-) m6A CDS       24284625//24209618//25456834//24981863//26404942//27773536//22575960//22608085
chr5:16701453-16701454(-) m6A CDS       24284625//24209618//25456834//24981863//26404942//27773536//22575960//22608085
chr5:16701486-16701487(-) m6A CDS       24284625//24209618//25456834//24981863//26404942//27773536//22575960//22608085
chr5:16701732-16701733(-) m6A CDS       24284625//24209618//25456834//24981863//27773536//22575960
chr5:16701807-16701808(-) m6A CDS       24284625//24209618//25456834//24981863//27773536//22575960//22608085
chr5:16701847-16701848(-) Cm CDS       -
chr5:16701863-16701864(-) m6A CDS       24284625//24209618//25456834//24981863//27773536//22575960//22608085
chr5:16701872-16701873(-) m6A CDS       24284625//24209618//25456834//24981863//27773536//22575960//22608085
chr5:16701884-16701885(-) m6A CDS       24284625//24209618//25456834//24981863//27773536//22575960//22608085
chr5:16701920-16701921(-) m6A CDS       24284625//24209618//25456834//24981863//27773536//22575960//22608085
chr5:16701942-16701943(-) m1A CDS       26863196
chr5:16703039-16703040(-) m1A CDS       26863196
chr5:16703074-16703075(-) m6A CDS       24284625//24209618//25456834//24981863//27773536//22608085
chr5:16703116-16703117(-) m6A CDS//exon       24284625//24209618//25456834//24981863//27773536//22608085
chr5:16711241-16711242(-) m6A CDS//exon//intron       22575960
chr5:16711252-16711253(-) m6A CDS//exon//intron       22575960
chr5:16741918-16741919(-) m6A 5'UTR//exon//intron       24981863
chr5:16741937-16741938(-) m6A 5'UTR//exon//intron       24981863
chr5:16741943-16741944(-) m6A 5'UTR//exon//intron       24981863
chr5:16741972-16741973(-) m6A 5'UTR//exon//intron       24981863
chr5:16742032-16742033(-) m6A 5'UTR//intron       24981863
chr5:16762690-16762691(-) m6A CDS       24981863//26404942
chr5:16762743-16762744(-) m6A CDS       26404942
chr5:16763602-16763603(-) m6A CDS       26404942
chr5:16763620-16763621(-) m6A CDS       26404942
chr5:16766273-16766274(-) m6A CDS       24981863
chr5:16769185-16769186(-) m6A CDS       24981863
chr5:16769229-16769230(-) m6A CDS       24209618//24981863
chr5:16783555-16783556(-) m6A CDS       26404942
chr5:16794910-16794911(-) m6A CDS       24284625
chr5:16877812-16877813(-) m6A CDS//intron       24209618
chr5:16916179-16916180(-) m6A CDS//intron       24209618
chr5:16916225-16916226(-) m6A 5'UTR//intron       24209618
chr5:16916373-16916374(-) m6A 5'UTR//intron       24209618
chr5:16916402-16916403(-) m6A 5'UTR//intron       24209618
chr5:16916412-16916413(-) m6A 5'UTR//intron       24209618
chr5:16935919-16935920(-) m6A 5'UTR       24209618//27773536
chr5:16935930-16935931(-) m6A 5'UTR       24284625//27773536
chr5:16935983-16935984(-) m6A 5'UTR       24284625//24981863//27773536
chr5:16936060-16936061(-) m6A 5'UTR       24284625//25456834//24981863//26404942//27773536//22575960//22608085
chr5:16936070-16936071(-) m6A 5'UTR       24284625//25456834//24981863//26404942//27773536//22575960//22608085
chr5:16936086-16936087(-) m6A 5'UTR       24284625//25456834//24981863//26404942//22575960//22608085
chr5:16936102-16936103(-) m6A 5'UTR       24284625//25456834//24981863//26404942//22575960//22608085
chr5:16936135-16936136(-) m6A 5'UTR       24284625//25456834//24981863//26404942//27773536//22575960
chr5:16936140-16936141(-) m1A 5'UTR       26863196
chr5:16936152-16936153(-) m6A 5'UTR       24284625//25456834//24981863//26404942//27773536//22575960
chr5:16936358-16936359(-) m6A 5'UTR       27773536//22575960

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate MYO10
Cytoplasm Nasopharyngeal carcinoma cells     20498841
Cytosol HeLa-S3 cells     -
Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539
Exosome Blood     -
Nucleus Nasopharyngeal carcinoma cells     20498841
Nucleus Colon cancer cells     24393600
Nucleus HCC cell line (HepG2)|HeLa-S3 cells     -

Interaction Network (The top 100 interactions):


Interactor1: hcmv-miR-US25-1-5p
Interactor2: MYO10

Evidence Support:


Strong-Evidence RISC-IP
Support Database ViRBase

References:


PMID 20585629 Target region 5'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line HEK293 cells Interactor2 expression None
Description Here, we identify cellular transcript targets of one of the most highly expressed HCMV encoded miRNAs, miR-US25-1, using a recently developed biochemical approach called RISC immunoprecipitation. Strikingly, the majority of identified transcripts contained miR-US25-1 target sites within the 5'UTR rather than the 3'UTR.

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